A5101760760- Pharmacological Effects of Natural Compounds
- Supercapacitor Materials and Fabrication
- Conducting polymers and applications
- Medicinal Plants and Bioactive Compounds
- Advanced battery technologies research
- Plant-based Medicinal Research
- Treatment of Major Depression
- Endoplasmic Reticulum Stress and Disease
- AI and Multimedia in Education
- Autophagy in Disease and Therapy
- Ginseng Biological Effects and Applications
- Heat shock proteins research
- Biochemical effects in animals
- Tea Polyphenols and Effects
- Tryptophan and brain disorders
Central South University
2013-2024
Second Xiangya Hospital of Central South University
2018-2024
Xiangya Hospital Central South University
2022
Changsha University
2020
L-theanine, originally found in green tea, elicits various physiological effects, such as promoting relaxation, improving concentration and learning ability, providing antianxiety-like antidepressant-like properties. This study aims to investigate the effects of L-theanine (2 mg/kg) on monoamine levels an animal model depression. The effect l-theanine symptoms depression was examined through open-field test, sucrose preference forced swim test. neurotransmitters that involve serotonin...
Abstract The neurotoxicity of Semen Strychni has been reported recently in several clinical cases. Therefore, this study was conducted to investigate the role HMGB1 a model induced by and assess potential alleviating effects glycyrrhizic acid (GA), which is associated with regulation release. Forty-eight SD rats were intraperitoneally injected extract (175 mg/kg), followed oral administration GA (50 mg/kg) for four days. After treatment SS GA, neuronal degeneration, apoptosis, necrosis...
Semen Strychni has long been used for the treatment of rheumatoid arthritis, facioplegia and myasthenia gravis due to its anti-inflammation anti-nociceptive properties in China. However, fatal neurotoxicity limited wider clinical application. To investigate acute toxicity induced by detoxification liquorice, we evaluated inflammation, oxidative stress translocation high mobility group box 1 (HMGB1) rats. As a result, there were obvious inflammation hippocampus after extracts (STR) Liquorice...
A type of redox flow battery, based on lead (II) dissolved in the electrolyte, has emerged as possible system for energy storage. However, formation dendrite and evolution hydrogen last stage charge have limited application soluble batteries. comparison study electrochemical behavior polyaniline (PANI) suspension indicates that response PANI flowing mode significantly differs from static state, exhibiting good transfer property due to continuous renewal microparticles by suspension....
Mild hypothermia can induce apoptotic cell death in many cancer cells, but the underlying mechanisms remain unclear. In a genetic screen Caenorhabditis elegans , we found that impaired endoplasmic reticulum unfolded protein response (UPR ER ) increased animal survival after cold shock. Consistently, normal human lung decreasing culture temperature from 37 to 30 °C activated UPR and promoted death. However, adenocarcinoma cells were induction resistant hypothermia‐induced Mechanistically,...
Semen Strychni, a traditional Chinese medicine (TCM), has been widely used to treat paraplegia, facial nerve palsy and myasthenia gravis. However, its clinical application is greatly limited due fatal toxicity. To investigate the acute toxicity of Strychni detoxification effect licorice, high-performance liquid chromatography tandem quadrupole time-of-flight mass spectrometry (HPLC-Q-TOF/MS) based urinary metabolomics method was developed in this study. After intraperitoneal injection rats...
In order to improve the stability of constant temperature control for indoor environment buildings, a design method optimisation system buildings' based on internet things (IoT) is proposed. The divided into two parts – algorithm and hardware structure conduct overall framework analysis functional component system. time-delay feedback error compensation adopted optimise law buildings. test results show that minimum root-mean-square designed 0.021, which significantly reduces system,...