A5021593726- Synthesis and biological activity
- Synthesis of β-Lactam Compounds
- Synthesis and Biological Evaluation
- Synthesis and Catalytic Reactions
- Click Chemistry and Applications
- Crystal structures of chemical compounds
- Multicomponent Synthesis of Heterocycles
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Chemical Synthesis and Analysis
- Asymmetric Synthesis and Catalysis
- Synthesis and Characterization of Heterocyclic Compounds
- CO2 Reduction Techniques and Catalysts
- Synthesis and Characterization of Pyrroles
- Hydrogels: synthesis, properties, applications
- Thermodynamic properties of mixtures
- Metal complexes synthesis and properties
- Phase Equilibria and Thermodynamics
- Crystallography and molecular interactions
- Synthesis of Organic Compounds
- Synthesis of heterocyclic compounds
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Luminescence Properties of Advanced Materials
- Advanced Drug Delivery Systems
- Catalytic C–H Functionalization Methods
Acharya Nagarjuna University
2011-2024
University of Madras
2010-2023
Government of Haryana
2023
National Institute of Mental Health and Neurosciences
2022
Max Planck Institute for Polymer Research
2017-2020
National Botanical Research Institute
2015
University of Hyderabad
2014-2015
Bharathiar University
2010
Sri Venkateswara University
2002-2006
Nanographenes, namely polycyclic aromatic hydrocarbons (PAHs) with nanoscale dimensions (>1 nm), are atomically precise cutouts from graphene. They represent prime models to enhance the scope of chemical and physical properties graphene through structural modulation functionalization. Defined nitrogen doping in nanographenes is particularly attractive due its potential for increasing number π-electrons, possibility introducing localized antiaromatic ring elements. Herein we present...
Abstract The vast potential of organic materials for electronic, optoelectronic and spintronic devices entails substantial interest in the fabrication π-conjugated systems with tailored functionality directly at insulating interfaces. On-surface such on non-metal surfaces remains to be demonstrated high yield selectivity. Here we present synthesis polyaromatic chains metallic substrates, layers, solid state. Scanning probe microscopy shows formation azaullazine repeating units Au(111),...
Abstract We have developed a one‐pot synthesis of polycyclic fused heterocyclic derivatives by the [3+2] cycloaddition Baylis–Hillman adducts (BHA) derived from 4‐oxoazetidine‐2‐carbaldehydes as dipolarophiles. The BHA methyl acrylate reacted with azomethine ylides generated sarcosine or proline, and diketone isatin to give unexpected pyrrolo/pyrrolizinoquinolinone derivatives. products contain three rings (lactone, pyrrolidine, lactam) at single C–C junction. Similar reactions carried out...
The antibacterial activity of β-lactam derived polycyclic fused pyrrolidine/pyrrolizidine derivatives synthesized by 1, 3-dipolar cycloaddition reaction was evaluated against microbes involved in dental infection. Fifteen compounds were screened; among them compound 3 showed efficient an ex vivo dentinal tubule model and mice infectious model. In silico docking studies greater affinity to penicillin binding protein. Cell damage observed under Scanning Electron Microscopy (SEM) which further...
Excess molar volume, excess isentropic compressibility, deviation in viscosity, and Gibbs free energy of activation viscous flow for binary mixtures Hexylene glycol (2-methyl-pentanediol-2,4 or MPD) with aliphatic ketones (4-hydroxy-4-methyl-pentan-2-one (J1), 4-methyl-pentan-2-one (J2), pentan-2-one (J3)) components selected compositions were determined from the measured values densities (ρ), viscosities (η), speeds sound (u) pure their 303.15 K to 313.15 K. The results analysed terms...
For the first time TFAA/H3PO4 has facilitated direct and metal-free N-acylation of carbazoles leading to a number N-acylated derivatives. Several these compounds were found be promising when tested for their anti-proliferative properties against oral cancer cell lines.
Healthcare-associated infections (HAI) are prime health task worldwide and issue of patient safety besides intensifying antimicrobial drug resistance. It is essential to formulate structurally fascinating novel, active cost-effective anti-microbial drugs possessing a peculiar way action capable overcoming the resistance effectively combat this disease. The synthesized spiro-heterocyclic hybrids (SHHs) were elucidated through spectroscopic analysis assessed for their in vitro activity by agar...
A facile synthesis of tri- and tetracyclic fused chromeno pyrrole derivatives has been accomplished by intramolecular cycloaddition reaction azomethine ylides generated from cyclic/acyclic secondary amino acids with O-allylated salicylaldehydes obtained Morita–Baylis–Hillman carbonates β-lactam aldehyde. The stereochemistry the cycloadducts was confirmed on basis single crystal X-ray diffraction data.
Abstract α‐Hydroxy carboxylic acids are synthesized in 80–86% isolated yields by electrochemical carboxylation of methyl aryl ketones the presence carbon dioxide (1 atm.) using a platinum cathode and sacrificial magnesium anode at constant current density 10 mA/cm2. Reversibility carbonyl group reduction generation anionic radical were shown cyclic voltammetry.