A5084942774- Cardiac, Anesthesia and Surgical Outcomes
- Wound Healing and Treatments
- Employment and Welfare Studies
- Gender, Labor, and Family Dynamics
- Global Health Care Issues
- Financial Literacy, Pension, Retirement Analysis
- Clinical Nutrition and Gastroenterology
- Immune Response and Inflammation
- Pediatric Hepatobiliary Diseases and Treatments
- Anorectal Disease Treatments and Outcomes
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Surgical Treatments
- Global Health Workforce Issues
- Social Issues and Policies
- Diverticular Disease and Complications
- Esophageal and GI Pathology
- demographic modeling and climate adaptation
- Clinical practice guidelines implementation
- Mycobacterium research and diagnosis
- Periodontal Regeneration and Treatments
- Retirement, Disability, and Employment
- Colorectal Cancer Screening and Detection
- Diet and metabolism studies
- Antibiotic Resistance in Bacteria
- Education Systems and Policy
University Hospital Galway
1994-2023
Trinity College Dublin
2021-2022
Economic and Social Research Institute
2019-2022
University College Dublin
1994-2020
Queen's University Belfast
2002-2013
William Harvey Research Institute
2010
King's College London
2010
GTx (United States)
2002
Royal Victoria Eye and Ear Hospital
2002
Mater Misericordiae University Hospital
1993-2000
This paper simulates the impact that Covid-19 related job losses will have on family incomes and public finances. It finds in central 'medium' unemployment scenario of 600,000 losses, around 400,000 families see their disposable income fall by more than 20 per cent absence policy changes, with proportionately larger for those higher families. Measures announced Government – notably flat-rate Pandemic Unemployment Payment €350 week reduce numbers exposed to such extreme about a third, but at...
Recently there has been much interest in the use of arginine to stimulate immune responses and promote wound healing. In present study, effect an oral supplementation with on metabolism 45 healthy, nonsmoking, elderly volunteers was investigated. Subjects were divided into two groups that received either aspartate (17 g free arginine) (n = 30) or a placebo 15). The supplements taken for period 14 days. Dietary intake food not controlled. Blood chemistry, lipid profiles, as index nutritional...
Carbapenem resistance in Enterobacterales is a public health threat. Klebsiella pneumoniae carbapenemase (encoded by alleles of the bla KPC family) one most common transmissible carbapenem mechanisms worldwide. The dissemination historically has been associated with distinct K. lineages (clonal group 258 [CG258]), particular plasmid family (pKpQIL), and composite transposon (Tn 4401 ).
While population health and welfare can be improved through the provision of non-cash benefits, such as free healthcare, many improving schemes have low rates take up amongst those eligible for a benefit. One interesting example this is Medical Card scheme in Ireland. Cards are benefit that provide primary, community, hospital care, well heavily subsidised prescriptions drugs, below specific income means-test threshold. However, despite significant benefits afforded by Card, people forego...
Fibroblasts are fundamental to successful wound healing. We hypothesized that the induction and regulation of various fibroblast functions (proliferation, collagen synthesis, remodeling) determined by environment. examined effect fluid (WF), as a reflection environment, on phenotypic expression normal dermal (NF) wound-harvested fibroblasts (WHF). WF WHF were obtained from implanted polyvinyl alcohol sponges in 10-day-old wounds. NF used between one three passages. Proliferative function was...
Supplemental L-arginine has been shown to enhance thymic and T-cell responses in rodents. We examined the ability of supplemental dietary induce function athymic nude mice that lack a normally developed system. Groups male (nu/nu) (Balb/c background) 7 8 weeks old were given for 2 1.2% arginine hydrochloride solution drinking, whereas controls received acidified tap water. All ingested standard laboratory chow. In first experiment, arginine-supplemented animals had significantly greater...
This study aimed to determine the effect of LP229v on intestinal permeability and tumour necrosis factor (TNF) p55 receptor concentrations in patients with obstructive jaundice undergoing biliary drainage.Patients drainage were recruited randomized into three groups receive Lactobacillus plantarum 299v (LP299v), inactivated LP299v (placebo) or water. These administered daily at noon until 7 days after drainage. Intestinal was measured using lactulose/mannitol (L/M) dual sugar absorption test...
Objective To determine whether intestinal fibroblasts in patients with Crohn’s disease (CD) have an enhanced capacity to reorganize collagen and thus cause stricture formation. Summary Background Data Stricture formation is a characteristic feature of CD that may distinguish it from other forms inflammatory bowel disease. Methods Fibroblasts were obtained at surgery the colon ileum ulcerative colitis (UC) control patients. Primary fibroblast cultures by explant technique. Fibroblast...
Abstract Background Healthcare-associated wastewater and asymptomatic patient reservoirs colonized by carbapenemase-producing Enterobacterales (CPE) contribute to nosocomial CPE dissemination, but the characteristics dynamics of this remain unclear. Methods We systematically sampled sites (n = 4488 samples; 349 sites) patients 1247) across six wards over 6–12 months understand blaKPC-associated (KPC-E) diversity within these transmission in a healthcare setting. Up five KPC-E-positive...
Cardiac complications from a pancreatic mediastinal pseudocyst are rare. Pericardial effusions associated with pancreatitis have been reported only very occasionally. To the best of our knowledge, direct extension into pericardial sac causing tamponade has not described before. We present case in which masquerading as effusion dissected mediastinum, eroding and life-threatening tamponade. A catheter was placed producing rapid symptomatic relief. Surgery avoided by use octreotide an adjuvant...
PURPOSE: Colonic mucosal metabolism of butyrate may be impaired in ulcerative colitis. In this study we sought to confirm observation, determine if a similar change occurs Crohn's colitis, and establish whether panenteric disorder exists either condition. METHODS: With use microculture technique, metabolic fluxes of14[C]-labeled and14[C]-labeled glutamine were measured as14[C] carbon dioxide production biopsy specimens from the colon ileum patients with healthy bowel. Results expressed as...