A5006512918- Hemodynamic Monitoring and Therapy
- Cardiac, Anesthesia and Surgical Outcomes
- Blood Pressure and Hypertension Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Non-Invasive Vital Sign Monitoring
- Cardiovascular Health and Disease Prevention
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Cardiac Arrest and Resuscitation
- Cardiac Imaging and Diagnostics
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cerebrovascular and Carotid Artery Diseases
- Heart Rate Variability and Autonomic Control
- Takotsubo Cardiomyopathy and Associated Phenomena
- Acute Ischemic Stroke Management
- Cardiovascular Function and Risk Factors
- Anesthesia and Sedative Agents
- Antibiotics Pharmacokinetics and Efficacy
- Optical Imaging and Spectroscopy Techniques
- Acute Kidney Injury Research
- Cerebrospinal fluid and hydrocephalus
- Infrared Thermography in Medicine
- Nosocomial Infections in ICU
- Sleep and Work-Related Fatigue
Université de Bordeaux
2017-2025
Hôpital Pellegrin
2018-2025
Centre Hospitalier Universitaire de Bordeaux
2018-2024
Inserm
2018-2024
Bordeaux Population Health
2018-2024
Institut Bergonié
2023
Committee on Publication Ethics
2017
Mini-fluid challenge of 100 ml colloids is thought to predict the effects larger amounts fluid (500 ml) in intensive care units. This study sought determine whether a low quantity crystalloid (50 and could 250 mechanically ventilated patients operating room.A total 44 undergoing neurosurgery were included. Volume expansion (250 saline 0.9%) was given maximize cardiac output during surgery. Stroke volume index (monitored using pulse contour analysis) pressure variations recorded before after...
In mechanically ventilated patients, an increase in cardiac index during end-expiratory-occlusion test predicts fluid responsiveness. To identify this rapid index, continuous and instantaneous monitoring is necessary, decreasing its feasibility at the bedside. Our study was designed to investigate whether changes velocity time integral peak obtained using transthoracic echocardiography maneuver could predict
End-expiratory occlusion test (EEOT) has been proposed to predict fluid responsiveness in mechanically ventilated intensive care unit patients. The utility of this during low-tidal-volume ventilation remains uncertain. This study aimed determine whether hemodynamic variations induced by EEOT could the effect volume expansion patients with protective operating room.Forty-one undergoing neurosurgery were included. Stroke and pulse pressure continuously recorded using contour analysis before...
Augmented renal clearance (ARC) is recognized as a leading cause of β-lactam subexposure when conventional dosing regimens are used. The main objective was to compare the clinical outcome ARC patients treated by or increased for first episode hospital ventilator-acquired pneumonia (HAP-VAP).In this single-center, retrospective study, every patient HAP-VAP included during two 15-month periods, before (Control period) and after (Treatment modification local antibiotic therapy protocol. defined...
Many maneuvers assessing fluid responsiveness (minifluid challenge, lung recruitment maneuver, end-expiratory occlusion test, passive leg raising) are considered as positive when small variations in cardiac index, stroke volume variation or pulse pressure occur. Pulse contour analysis allows continuous and real-time volume, estimations. To use these with analysis, the knowledge of minimal change that needs to be measured by a device recognize real (least significant change) has studied. The...
We determined whether an audit on the adherence to guidelines for hospital-acquired pneumonia (HAP) can improve outcomes of patients in intensive care units (ICUs).This study was conducted at 35 ICUs 30 hospitals. included consecutive, adult hospitalized 3 days or more. After a 3-month baseline period followed by dissemination recommendations, compliance recommendations (audit period) cluster-randomized trial. randomly assigned either receive and feedback (intervention group) participate...
To provide recommendations for the anaesthetic and peri-operative management thrombectomy procedure in stroke patients DESIGN: A consensus committee of 15 experts issued from French Society Anaesthesia Intensive Care Medicine (Société Française d'Anesthésie et Réanimation, SFAR), Association French-language Neuro-Anaesthetists (Association des Neuro-Anesthésistes Réanimateurs de Langue Francaise, ANARLF), Neuro-Vascular Francaise Neuro-Vasculaire, SFNV), Neuro-Radiology Neuro-Radiologie,...
Hyperoxia is associated with increased morbidity and mortality in the intensive care unit. Classical noninvasive measurements of oxygen saturation pulse oximeters are unable to detect hyperoxia. The Oxygen Reserve Index (ORI) a continuous parameter provided by multi-wave oximeter that can Primary objective was evaluate diagnostic accuracy ORI for detecting arterial tension (PaO2) > 100 mmHg neurocritical patients. Secondary objectives were test ability PaO2 120 oximetry (SpO2) mmHg.In this...
Abstract Background Dynamic arterial elastance (Eadyn), defined as the ratio between pulse pressure variations and stroke volume variations, has been proposed to assess functional load. We evaluated evolution of Eadyn during expansion effects neosynephrine infusion in hypotensive preload-responsive patients. Methods In this prospective bicentre study, we included 56 mechanically ventilated patients operating room. Each patient had infusion. Stroke were obtained using esophageal Doppler,...
Abstract Linezolid is an alternative to vancomycin for treating Gram-positive central nervous system (CNS) healthcare-associated infections. The recommended dosing regimen remains debated. PK-Pop-LCR a prospective population pharmacokinetic-pharmacodynamic multicenter study which included brain injured patients with external ventricular drainage receiving linezolid at different regimens. cerebrospinal fluid (CSF) penetration of was investigated and pharmacokinetic model developed using...
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Abstract Background Cardiac complications due to non-traumatic subarachnoid hemorrhage (SAH) are usually described using classical echocardiographic evaluation. Strain imaging appears have better sensitivity than standard markers for the diagnosis of left ventricular dysfunction. The aim this study was determine prevalence cardiac dysfunction defined as a Global Longitudinal (GLS) ≥ − 20% in patients with good-grade SAH (WFNS 1 or 2). Methods Seventy-six were prospectively enrolled and...