- Biomimetic flight and propulsion mechanisms
- Fluid Dynamics Simulations and Interactions
- Micro and Nano Robotics
- Ship Hydrodynamics and Maneuverability
- Underwater Vehicles and Communication Systems
- Glioma Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Cavitation Phenomena in Pumps
- Aerospace Engineering and Energy Systems
- Distributed Control Multi-Agent Systems
- Gastrointestinal Tumor Research and Treatment
- Electric and Hybrid Vehicle Technologies
- Circular RNAs in diseases
- Lattice Boltzmann Simulation Studies
- Glycosylation and Glycoproteins Research
- Biological Activity of Diterpenoids and Biflavonoids
- Brain Tumor Detection and Classification
- Flavonoids in Medical Research
- Colorectal Cancer Treatments and Studies
- Neurofibromatosis and Schwannoma Cases
- Cancer, Lipids, and Metabolism
- Traditional Chinese Medicine Analysis
- Aerodynamics and Fluid Dynamics Research
- Lung Cancer Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
Shanghai University of Traditional Chinese Medicine
2025
Shanghai University of Medicine and Health Sciences
2025
National University of Defense Technology
2022-2024
Fifth Affiliated Hospital of Zhengzhou University
2020
Second Affiliated Hospital of Zhengzhou University
2016-2019
The median and/or paired fin (MPF) swimming mode of fish has extremely strong maneuverability, which is urgently needed for unmanned underwater vehicles. Therefore, determining the mechanism greater maneuverability in MPF particularly important. To fill research gap entire turn maneuvering process under self-propulsion, a numerical solution method three degree-of-freedoms self-propelled biomimetic robotic (BRF) coupled with fluid dynamics and body were established. Our results revealed that...
In contrast to other swimming modes, the motions of fins in labriform mode can be categorized into drag-based and lift-based mode, which differ terms thrust generation mechanisms. This variance mechanisms gives unique advantages underwater propulsion. The term indicates that propulsion occurs due oscillatory movements pectoral fins. Herein, identify key features locomotion, numerical simulations a self-propelled biomimetic robotic fish with Reynolds number (Re) up 3 000 are performed. study...
The mechanism of fast and high maneuvering swimming fish under the cooperative propulsion multiple fins has not been fully studied. To fill research gap in process numerical simulation on motion performance, hydrodynamic characteristics, flow field fish-like swimmers cruising maneuverability coupled body and/or caudal fin (BCF) mode median paired (MPF) mode, a solution method multibody dynamics coupling combined body-caudal-pectoral is established. efficient BCF MPF systematically Our...
The unique structural configurations of amphibious vehicles, designed for dual land–water operations, pose significant challenges hydrodynamic stability during water navigation. This study systematically investigated the performance and motion response a light high-speed vehicle (HSAV-II) under oblique inflow conditions. working conditions HSAV-II drift with five incoming flow angles (β) (0°, 5°, 10°, 15° 20°) were considered. computational fluid dynamics method, based on steady Reynolds...
Glioblastoma (GBM) is one of the most deadly primary malignant brain tumors in adults. R132H mutation isocitrate dehydrogenase 1 (IDH1) predicts a better prognosis GBM. IDH1-R132H associated with increased hypoxia-inducible factor-1α (HIF-1α) expression GBM tumors. However, molecular mechanism underlying IDH1-R132H-HIF-1α signaling still unclear.We aimed to investigate pathway regulation GBM.U87 and U251 cells xenograft tumor mice were used.We found that overexpression decreased cell...
According to the WHO, cribriform pattern is a subtype of acinar (Aci) predominance in invasive adenocarcinoma (ADC) lung. Recently, several studies have demonstrated poor prognosis patients with predominance. This study was performed examine correlations clinicopathology, molecular features and ADC.Histological subtypes were evaluated 279 who underwent complete resection for ADC. Patients Aci-predominant divided into two subgroups according percentage cancer (≥5% vs <5%). Clinicopathological...
In this study, the resistance characteristics of amphibious vehicle in transitional stage are studied. A deformable track wheel is designed and its effect on vehicle's The numerical calculation method based RANS solver towing test used to analyse hydrodynamic performance vehicle. Based comparison model with no wheel, influence wheels additional at groove fault inclination angles front rear deformation studied respectively. principle configuration drag analysed expounded terms pressure...
To study the self-propelled swimming performances and mechanisms of biomimetic robotic fish with undulating fins (BRFUF) under different waveforms, a numerical simulation system coupled body dynamics fluid was established to starting, accelerating, cruising processes in median/paired fin mode. A systematic parametric carried out on performance BRFUF cooperative propulsion two fins, mechanism thrust generation influence waveform kinematic parameters were analyzed based hydrodynamic...
Abstract. In order to reduce the resistance and increase speed for a high-speed wheeled amphibious vehicle, wheel-retracting mechanism was applied walking influence researched. Firstly, obtain reliable numerical method, realizable shear stress transport (SST) k-ω turbulence model computational fluid dynamic (CFD) built by an overset mesh technique used compared with corresponding tests. Secondly, effect of wheels' flip angle on resistance, heave pitch investigated. Then, wheel well optimized...
Objective To investigate the expression of epidermal growth factor receptor (EGFR) in tissue non-small cell lung cancer (NSCLC), and carbohydrateantigen 125 (CA125), 199 (CA199) postoperative NSCLC patients with bone metastasis without metastasis, discuss roles EGFR, CA125 CA199 metastasis. Methods Sixteen cases served as experimental group, 16 control group. The EGFR cancer, serum levels were determined. Results The strong positive rate was 81.2% group 56.3% 43.8% respectively....
Objective To investigate the role of ATRX and P53 gene mutations in classification diffuse glioma Chinese. Methods A total 89 cases astrocytoma (IDH mutation) or wild type) all levels oligodendroglioma from 2016 to 2017 were collected, detected expression protein over by immunohistochemistry, analyzed their different types gliomas. Results The ratio loss (17/24) was higher than that oligodendrogliomas (3/16), P<0.01; (15/24) (1/16), (71%, 17/24) wild) (41%, 20/49),...