A5084063622- Intracranial Aneurysms: Treatment and Complications
- Neurosurgical Procedures and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular Malformations Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Amyotrophic Lateral Sclerosis Research
- Cerebral Venous Sinus Thrombosis
- Acute Ischemic Stroke Management
- Moyamoya disease diagnosis and treatment
- Amino Acid Enzymes and Metabolism
- Meningioma and schwannoma management
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrospinal fluid and hydrocephalus
- Biochemical effects in animals
- Neurogenetic and Muscular Disorders Research
- Sinusitis and nasal conditions
- Mitochondrial Function and Pathology
- Infectious Encephalopathies and Encephalitis
- Spinal Hematomas and Complications
- Metabolism and Genetic Disorders
- Venous Thromboembolism Diagnosis and Management
- Glioma Diagnosis and Treatment
- Spinal Fractures and Fixation Techniques
- Infectious Diseases and Tuberculosis
- Bacterial Infections and Vaccines
Jichi Medical University
2019-2024
Jichi Medical University Saitama Medical Center
2019-2024
Tokyo Medical and Dental University
2000-2019
Tokyo Medical and Dental University Hospital
2013
Tsuchiura Kyodo General Hospital
2013
National Disaster Medical Center
2007-2011
National Hospital Organization
2007-2011
Roosevelt Hospital
2006
New York Proton Center
2006
Mount Sinai Beth Israel
2004-2005
SUMMARY The incorporation of [U‐ 14 C]leucine into the protein brain cortex slices from rats poisoned with methylmercury thioacetamide was markedly inhibited before development neurological symptoms and when oxygen consumption, aerobic anaerobic glycolysis sulphydryl enzyme activities were unchanged. After appearance symptoms, consumption decreased significantly, while lactic acid formation did not change under conditions, but slightly conditions. three enzymes (Mg‐activated ATPase,...
The time course of entry radioactive carbon from intravenously administered [U- 14 C]-glucose into free amino acids in the brains rats has been studied using an automatic acid analyzer coupled through a flow cell with scintillation counter. Radioactivity appeared rapidly alanine, aspartic acid, glutamic glutamine, and γ-aminobutyric as previously shown, unknown ninhydrin-positive substance present very small amount. Urea, serine, glycine became slightly radioactive. Four hours after giving...
A multimodal neuronavigation system using metabolic images with PET and anatomical from MR is described here for glioma surgery. The efficacy of the was evaluated by comparing results that conventional navigation system, which routinely uses CT imaging as guides.Thirty-three patients cerebral underwent 36 operations aid either a or system. All were preliminarily examined l-methyl-[11C] methionine (MET) surgical planning. Seventeen performed integrating MET-PET images. other 19 based solely...
<i>Background:</i> Patients with poor-grade aneurysmal subarachnoid hemorrhage (SAH) presenting large intracerebral (ICH) or sylvian hematomas (SylH) have poor outcomes due to the mass effect of significant brain stem compression following effect. On other hand, decompressive craniectomy (DC) can reduce morbidity and mortality in critically ill patients massive ischemic infarction severe head injury. However, role DC SAH is not fully understood. We investigated outcome ICH SylH....
Malignant gliomas are typically angiogenic and secrete high levels of VEGF. Hypoxia has been identified as an important regulator However, malignant express VEGF in both hypoxic perinecrotic vital tumor areas. In this study, we examined intracellular signaling pathways involved the secretion glioma cells under normoxic conditions. Human cell lines, T98G, U373MG, U87MG, A172, human fetal lung fibroblasts (HFL) were cultured with without IL-1beta VEGF, IL-1, IL-6, TNF-alpha measured ELISA....
Object. The authors investigated whether HydroCoils decreased coil compaction and aneurysm recanalization in a canine model of large, wide-necked, high-flow bifurcation aneurysm. Methods. Eleven experimental aneurysms were created. Two untreated (Group 1); three treated with standard platinum coils (Guglielmi Detachable Coils; Group 2); six framing filling 3). Comparative angiographic histopathological data analyzed at 2 weeks again 3 months. At months, the 1 remained patent without...
Studies using paper and column chromatography indicate that rat brain contains 0.03–0.08 μmole of β-alanine per gram tissue less than 0.01 μmole/g γ-amino-β-hydroxybutyric acid. After intravenous injection U- 14 C-glucose no radioactivity appeared in these two substances.
The time course of entry radioactive carbon from intravenously administered [U- 14 C]-glucose into protein in five brain regions rats was studied using an automatic amino acid analyzer coupled, through a flow cell, with scintillation counter. Radioactivity appeared protein-bound alanine and glutamic aspartic acids and, more slowly to much lesser extent, serine, proline, glycine; none detected any other bound acids. There appear be two main groups proteins, one which turns over than the...
Aneurysms of lenticulostriate artery (LSA) have rarely been reported. We present an extremely rare case bilateral aneurysm LSA, which spontaneously disappeared. A 59-year-old man presented to us with a decreased level consciousness. Twice repeated blood culture was negative. Computed tomography (CT) showed basal ganglia hemorrhage intraventricular extension and acute hydrocephalus. performed external ventricular drainage. Cerebral angiograms, on 3 days after the onset, disclosed two...