About
Contact & Profiles
A5000970321
Research Areas
- Acute Myeloid Leukemia Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Genetic factors in colorectal cancer
- PARP inhibition in cancer therapy
- DNA Repair Mechanisms
- Cholinesterase and Neurodegenerative Diseases
- Ion channel regulation and function
- CAR-T cell therapy research
- RNA Research and Splicing
- Neuroscience and Neuropharmacology Research
- Cardiac electrophysiology and arrhythmias
- Immune Cell Function and Interaction
- Hematopoietic Stem Cell Transplantation
- Chronic Myeloid Leukemia Treatments
- Nicotinic Acetylcholine Receptors Study
- Hematological disorders and diagnostics
- Alzheimer's disease research and treatments
King's College London
2013-2024
University of Leeds
2010
Inactivation of the DNA mismatch repair pathway manifests as microsatellite instability, an accumulation mutations that drives carcinogenesis. Here, we determined whether instability in acute myeloid leukemia and myelodysplastic syndrome correlated with chromosomal poly (ADP-ribose) polymerase (PARP) inhibitor sensitivity through disruption function. Acute cell lines (n=12) primary samples (n=18), bone marrow mononuclear cells from high-risk patients (n=63) were profiled for using...
10.3324/haematol.2012.079251
article
EN
cc-by-nc
Haematologica
2013-01-24
10.1016/j.neuroscience.2010.01.020
article
EN
Neuroscience
2010-01-19
10.1016/j.brainres.2010.05.022
article
EN
Brain Research
2010-05-17
10.1182/blood.v126.23.1221.1221
article
EN
Blood
2015-12-03
10.1182/blood-2024-207101
article
EN
Blood
2024-11-05
10.1182/blood.v122.21.2792.2792
article
EN
Blood
2013-11-15
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