Reza Raoofian

ORCID: 0000-0003-3772-200X
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About
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Research Areas
  • Research on Leishmaniasis Studies
  • Trypanosoma species research and implications
  • Antibiotic Resistance in Bacteria
  • Photodynamic Therapy Research Studies
  • Cancer, Hypoxia, and Metabolism
  • Ubiquitin and proteasome pathways
  • Glaucoma and retinal disorders
  • Mosquito-borne diseases and control
  • Antifungal resistance and susceptibility
  • Genetic diversity and population structure
  • Ocular Infections and Treatments
  • Immunotherapy and Immune Responses
  • Oral microbiology and periodontitis research
  • RNA modifications and cancer
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Forensic and Genetic Research
  • Molecular Biology Techniques and Applications
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Gut microbiota and health
  • Endodontics and Root Canal Treatments
  • Genomics and Chromatin Dynamics
  • Lung Cancer Treatments and Mutations
  • Cancer-related gene regulation
  • Esophageal Cancer Research and Treatment
  • Inflammatory mediators and NSAID effects

Iranian Legal Medicine Organization
2015-2024

Tehran University of Medical Sciences
2009-2019

Islamic Azad University, Mashhad
2015-2019

Mashhad University of Medical Sciences
2011-2015

University of Tehran
2008

Multidrug-resistant Acinetobacter baumannii infections are serious challenges for clinicians because of A. propensity to acquire resistance a wide spectrum antimicrobial agents. In this study, 91 isolates from patients in tertiary intensive care units three university hospitals the north, central, and south Iran were selected tested susceptibility 22 antimicrobials; amplified restriction fragment polymorphism multiplex polymerase chain reaction methods used determine genetic relationships...

10.1089/mdr.2012.0233 article EN Microbial Drug Resistance 2013-06-15

Abstract The current study aimed to evaluate Y chromosome haplotypes obtained from 1353 unrelated Iranian males using the AmpFlSTRTM YfilerTM kit; out of identified were unique. haplotype diversity (HD) and discriminating capacity (DC) values 1.00000 0.997, respectively. Analysis genetic distance was performed molecular variance (AMOVA) multidimensional scaling plots (MDS), revealing a statistically significant difference between population previous data reported for other populations...

10.1186/s12864-024-10217-1 article EN cc-by BMC Genomics 2024-04-02

Multidrug resistant strains of Acinetobacter baumannii (MDR-AB) have emerged as alarming nosocomial pathogens among patients with burning.The current study aimed to determine the susceptibility A. species, carbapenems resistance patterns, and their association IS Aba 1 4 elements upstream bla OXA-like genes, distribution international clone (IC) isolates burning in Tehran, Iran.In study, 62 species from Iran, 2012 were evaluated for antimicrobial susceptibility, genetic relationships, ICs,...

10.5812/jjm.17167v2 article EN cc-by-nc Jundishapur Journal of Microbiology 2015-06-16

Carbapenem-resistant Acinetobacter baumannii (CR-AB) causes serious nosocomial infections, especially in ICU wards of hospitals, worldwide. Expression blaOXA genes is the chief mechanism conferring carbapenem resistance among CR-AB. Although some have been studied CR-AB isolates from Iran, their blaOXA-23-like not investigated. We used a multiplex-PCR to detect Ambler class A, B, and D carbapenemases 85 isolates, determined that 34 harbored genes. Amplified fragment length polymorphism...

10.3389/fmicb.2015.01249 article EN cc-by Frontiers in Microbiology 2015-11-13

Background: Vaginal flora of healthy women is dominated by Lactobacillus species which can prevent bacterial vaginosis.Objectives: The current study aimed to determine the differences in vaginal lactobacilli composition Iranian and vaginosis (BV) infected compared their cytotoxic effects with commercial probiotics.Patients Methods: One hundred seventy eight specimens were collected from BV women.Lactobacillus colonies obtained culturing on laked blood BHI MRS medias genetically defined 16s...

10.5812/ircmj.3533 article EN Iranian Red Crescent Medical Journal 2013-03-05

The mainstay therapy against leishmaniasis is still pentavalent antimonial drugs; however, the rate of antimony resistance increasing in endemic regions such as Iran. Understanding molecular basis to antimonials could be helpful improve treatment strategies. This study aimed recognize genes involved Leishmania tropica field isolates. Sensitive and resistant L. parasites were isolated from anthroponotic cutaneous patients drug susceptibility meglumine antimoniate (Glucantime®) was confirmed...

10.3347/kjp.2013.51.4.413 article EN Korean Journal of Parasitology 2013-08-30

Acinetobacter baumannii causes difficult-to-treat nosocomial infections, which often lead to morbidity due the development of antimicrobial drug resistance and expression virulence genes. Data regarding association colistin, a last treatment option, gene A. is scarce.We evaluated MLVA genotype, resistance, biofilm formation 100 isolates from burn patients, further compared in vitro vivo four genes among five colistin-resistant (Cst-R-AB) isolates. Five Cst-R-AB were tested; one present...

10.1186/s12941-018-0277-6 article EN cc-by Annals of Clinical Microbiology and Antimicrobials 2018-06-01

Widespread multidrug-resistant Acinetobacter baumannii (MDR-AB) strains have limited therapeutic options for treating intensive care unit (ICU) patients with MDR-AB infection in Iran. We aimed to evaluate diversity and antimicrobial susceptibility Tehran (Iran) address the need feasible effective control approaches against severe infections.We used amplified fragment length polymorphism (AFLP) minimum inhibitory concentration (MIC) determinations compare genotypic patterns of 100 isolates...

10.1089/mdr.2013.0146 article EN Microbial Drug Resistance 2014-07-16
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