- Hepatitis B Virus Studies
- Neurological Disease Mechanisms and Treatments
- Virus-based gene therapy research
- RNA modifications and cancer
- Plant Genetic and Mutation Studies
- Cancer Research and Treatments
- GABA and Rice Research
- Hepatitis C virus research
- Pluripotent Stem Cells Research
- Healthcare and Venom Research
- Liver Disease Diagnosis and Treatment
- Plant Molecular Biology Research
- Immune Cell Function and Interaction
- Medical Research and Treatments
- RNA Interference and Gene Delivery
- Gastric Cancer Management and Outcomes
- Traditional Chinese Medicine Studies
- Pharmacological Effects of Natural Compounds
- CRISPR and Genetic Engineering
- Monoclonal and Polyclonal Antibodies Research
- MicroRNA in disease regulation
- Regional Development and Environment
- Pancreatic function and diabetes
- Cancer-related gene regulation
- Plant Reproductive Biology
Carolinas Medical Center
2021-2024
Zhejiang A & F University
2023
Zimbabwe Open University
2023
Seoul National University
2023
University of Westminster
2022
Communication University of China
2022
Third Affiliated Hospital of Guangzhou Medical University
2022
Guangzhou Medical University
2022
University of California, Riverside
2020
National University of Mongolia
2020
Several nucleoside analogues (penciclovir, lobucavir, dioxalane guanine [DXG], 1-beta-2,6-diaminopurine [DAPD], L-FMAU, lamivudine) and acyclic phosphonate (adefovir, tenofovir) that are in clinical use, trials or under preclinical development for the treatment of hepatitis B virus (HBV) infections, were evaluated their inhibitory effect on replication a la- mivudine-resistant HBV variant containing methionine --> valine substitution (M550V) polymerase nucleoside-binding domain. The...
Ursolic acid is a promising anticancer agent. The current study aims to evaluate the single- and multiple-dose pharmacokinetics (PK) as well safety of ursolic nanoliposomes (UANL) in healthy volunteers patients with advanced solid tumors.Twenty-four single-dose PK were divided into three different groups, which received 37, 74, 98 mg/m(2) UANL. Eight administered 74 UANL daily for 14 days. UA plasma concentrations determined using ultra-performance liquid chromatograph-tandem mass...
This study investigates the feasibility of reducing manual image annotation costs in medical database construction by utilizing a step approach where Artificial Intelligence model(AI model) trained on previous batch data automatically pre-annotates next data, taking ultrasound thyroid nodule as an example. The used yolov8 AI model. During model training, addition to conventional augmentation techniques, methods specifically tailored for images were employed balance quantity differences...
We have used in situ hybridization (ISH) and immunohistochemistry (IHC) to investigate the kinetics of expression for FcεRI mRNA (α‐, β‐ γ‐chains), α‐chain protein product, as well phenotype mRNA‐ or protein‐positive cells allergen‐induced late‐phase skin reactions atopic subjects. Compared with diluent controls, there were significant increases total numbers + α‐, β‐and γ‐chains at all time‐points (6, 24 48 hr) after allergen challenge ( P <0·01). By double IHC/ISH γ‐chain macrophages,...