A5059927920- Neuroscience and Neuropharmacology Research
- Retinal Diseases and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Retinal Imaging and Analysis
- Aquaculture disease management and microbiota
- Alzheimer's disease research and treatments
- Glaucoma and retinal disorders
- Zebrafish Biomedical Research Applications
- Biochemical Analysis and Sensing Techniques
- Physiological and biochemical adaptations
- Endoplasmic Reticulum Stress and Disease
- Neurogenesis and neuroplasticity mechanisms
- GABA and Rice Research
- Retinal and Optic Conditions
- Cholinesterase and Neurodegenerative Diseases
- Traditional Chinese Medicine Analysis
- Intraocular Surgery and Lenses
- NF-κB Signaling Pathways
- Healthcare and Venom Research
- Medical Imaging Techniques and Applications
- Neuroendocrine regulation and behavior
- Autophagy in Disease and Therapy
- Cancer-related Molecular Pathways
- Quinazolinone synthesis and applications
- Agriculture, Soil, Plant Science
Jeju National University
2016-2025
Southwestern Medical Center
2024
Hoseo University
2024
The University of Texas Southwestern Medical Center
2024
Chungbuk National University Hospital
2020-2023
Korea University Medical Center
2023
Gangneung–Wonju National University
2022
Chungbuk National University
2022
Ophthalmology Associates (United States)
2021
Pusan National University
2021
// Rajapaksha Gedara Prasad Tharanga Jayasooriya 1, 4 , Matharage Gayani Dilshara 1 Ilandarage Menu Neelaka Molagoda Cheol Park 2 Sang Rul Seungheon Lee Yung Hyun Choi 3 and Gi-Young Kim Department of Marine Life Sciences, Jeju National University, 63243, Republic Korea Molecular Biology, College Natural Sciences Human Ecology, Dongeui Busan 47340, Biochemistry, Oriental Medicine, Dong-Eui 47227, Present address: Bioprocess Technology, Faculty University Rajarata, Mihintale 50300, Sri Lanka...
Ultraviolet (UV) irradiation is considered to be the primary environmental factor that causes skin damage. In present study, we investigated protective effect of dieckol (DK), a compound isolated from brown seaweed Ecklonia cava, against UVB-induced damage in human dermal fibroblasts (HDF cells). The results indicated DK effectively inhibited activity collagenase. remarkably reduced intracellular reactive oxygen species level and improved viability UVB-irradiated HDF cells. Besides,...
Article cKit Ligand (Stem Cell Factor)-Induced Immune Response via an Alternative Receptor in Human Cells Jihyung Hwang 1,†, Angela Reinert 2,†, Arthur Stem 2, Saerok Shim 1, Sinae Kim HeeJoon 3, Myungdal Yoon Seungheon Lee Donghwan Song Hyun Yoo Sunyoung Han 4, Mijeong Choi 5, Jared M. Brown 2,*, and Soohyun 1,3,* 1 Laboratory of Cytokine Immunology, Department Biomedical Science Technology, Konkuk University, Seoul 05029, Republic Korea 2 Pharmaceutical Sciences, Colorado Center for...
Although the cancer/testis antigen CAGE has been implicated in tumorigenesis, molecular mechanism of CAGE-promoted tumorigenesis not extensively studied. CT26Flag-CAGE cells, CT26 (mouse colon cancer cells) cells stably expressing CAGE, were established for better understanding tumorigenesis. Down-regulation decreased autophagic flux cells. showed binding to Beclin1, a mediator autophagy. enhanced autophagosomes formation. displayed greater tumor spheroid forming potential than did MicroRNA...
Abstract To investigate the changes in outer nuclear layer (ONL) thickness during anti-vascular endothelial growth factor (VEGF) treatment type 1 choroidal neovascularization (CNV) and its impact on vision. Type CNV eyes (n = 94) were retrospectively compared to normal control 35). Along with best-corrected visual acuity (BCVA), location of CNV, foveal ONL thickness, subretinal fluid height measured using optical coherence tomography (OCT) analyzed. Visual outcome OCT biomarkers compared. As...
Abstract It has been noted that restricting field of view (FoV) is effective to mitigate virtual reality (VR) sickness, but it prone reduce the immersiveness. We propose an FoV restriction approach VR sickness on mobile devices. The proposed includes a practical and reliable method for measuring effectively limiting Experimental result shows reduces by 31.4%. was successfully applied application.
Ziziphus jujuba is a plant, which bears fruits and seeds that are used for medicinal purposes in Traditional oriental medicine. The seed of Zizyphus var. spinosa (EZJ) has been also traditionally psychiatric disorders Chinese Korean medicines. Recent findings have indicated EZJ improves memory impairment, common symptom various neurological diseases. However, the effects on amyloid β (Aβ) toxicity, main cause Alzheimer's disease (AD), remain to be elucidated. To illuminate potential anti-AD...
이 연구의 목적은 mice를 이용하여 elevated plus-maze (EPM) test와 hole-board test를 통해 quercetin의 잠재적인 항불안 작용을 확인하고자 함이다. Quercetin을 1.25, 2.5, 5나 10 mg/kg의 용량으로 각각 행동시험을 측정하기 1 시간 전에 ICR mice에 경구투여하였다. 대조군은 동일한 양의 10% Tween 80을 투여하였고 양성대조군으로 buspirone 2 mg/kg을 투여하였다. 단회 투여하여 EPM 실시한 결과, 5 mg/kg 용량에서 open arm에 머문 및 진입한 횟수의 백분율이 control group과 비교하여 통계적으로 유의성 있게 증가하였다(p<0.05). 또한 quercetin을 구멍에 머리를 넣은 횟수가 quercetin와 flumazenil (<TEX>$GABA_A$</TEX> antagonist), WAY-100635 (<TEX>$GABA_{A-{\rho}}$</TEX>...
To investigate the visual/anatomical outcome of diabetic macular edema (DME) patients lost to follow-up (LTFU) for more than 1 year during intravitreal anti-VEGF treatment. A retrospective review 182 treatment-naïve DME was performed. Among them, we identified LTFU Visual acuity and anatomic outcomes at first visit, last visit before being LTFU, return after re-treatment were analyzed compared with those regular follow-up. Patients who had continuous visits assigned control group. Sixty...