A5026166917- Biosimilars and Bioanalytical Methods
- Effects of Environmental Stressors on Livestock
- Ovarian function and disorders
- Health Systems, Economic Evaluations, Quality of Life
- Global Cancer Incidence and Screening
- Thermoregulation and physiological responses
- Neutropenia and Cancer Infections
- Ethics in Clinical Research
- Body Composition Measurement Techniques
- Biomedical Ethics and Regulation
- Chemotherapy-related skin toxicity
- Cancer Treatment and Pharmacology
- Adipose Tissue and Metabolism
- Hormonal and reproductive studies
- Monoclonal and Polyclonal Antibodies Research
- Diet and metabolism studies
- Latin American socio-political dynamics
- Regulation of Appetite and Obesity
- Adipokines, Inflammation, and Metabolic Diseases
- Pharmaceutical Economics and Policy
- Rheumatoid Arthritis Research and Therapies
- Blood disorders and treatments
- BRCA gene mutations in cancer
National Institute of Quality
2020
Clinical Research Management
2011
Administración Nacional de Medicamentos, Alimentos y Tecnología Médica
2002
University of Buenos Aires
2002
Enerceptan (EtaBS) has been developed as a proposed biosimilar of etanercept.This randomized, multicenter, evaluator-blinded, noninferiority study conducted in Argentina included adults with active, moderate, and severe rheumatoid arthritis inadequate response to methotrexate. Subjects were randomly assigned 32 weeks treatment EtaBS (n = 99) or etanercept 51) at weekly 50-mg dose administered subcutaneously. Patients categorized according prior use biologic disease-modifying antirheumatic...
Introduction Medical research and development (R&D) is an undoubtedly relevant activity to drive innovation, improve healthcare policies bring patients treatment opportunities for common rare diseases. Equity inclusion are matters of concern in research. High-income countries’ teams more likely have impactful publications, grant funding, clinical trials than middle or low-income countries. Low budget allocations R&D existing gaps regulatory frameworks some obstacles growth....
We compared the efficacy, safety, and immunogenicity of a biosimilar recombinant human follicle-stimulating hormone (Folitime®) with Gonal-f® in women undergoing ovarian stimulation for in-vitro fertilization.This randomized (1:1), multicenter, assessor-blinded, non-inferiority, parallel-group, controlled study conducted at four infertility clinics Argentina included infertile normogonadotropic ages below 39 years, menstrual cycles 25/35 days body mass index 18-32 kg/m2 assisted reproductive...
The health care services managed by trade unions and known as "Obras Sociales" form the groundwork for Argentina's Social Security Health system. However, far from taking an equitable approach, these institutions highlight country's prevailing income disparities, which in turn lead to major differences access care. main focus of this study was reformulation social security policies within framework deregulation 1998 2000, analyzing effects on availability equity perspective. methodology used...
Abstract Objectives: To elucidate the relationship of hCG administration to glycemia, Non Esterified Fatty Acids (NEFA), leptin and adiponectin levels on experimental animals previously submitted a cafeteria diet, then Low Calorie Diet (LCD). Design: Forty-one rats were selected (21 females, 20 males) divided into seven (0-6) groups. Animals from groups 1 6 fed "cafeteria diet" with mean energy content 10% protein, 30% carbohydrate 60% fat. group 0 standard laboratory diet....
Our studies suggest that in experimental animals, submitted to a hypocaloric diet, the intrarectal administration of hCG (Human Chorionic Gonadotropin) decreases body fat and increases lean mass content relative values greater extent control animals who did not receive hCG.
This study evaluated the efficacy, safety, and immunogenicity of biosimilar pegfilgrastim (PegFilBS) originator (PegFilOR) in patients with stage 2-4 breast cancer.This phase III randomized, multicenter, evaluator-blinded, noninferiority recruited women cancer Argentina who were scheduled to receive chemotherapy. Stratification was based on stage. The primary end point duration severe neutropenia (DSN, margin: 1 day) first chemotherapy cycle. Secondary points assessed incidence neutropenia,...
Our studies suggest that in experimental animals, submitted to a hypocaloric diet, the intrarectal administration of hCG (Human Chorionic Gonadotropin) decreases body fat and increases lean mass content relative values greater extent control animals who did not receive hCG.
Abstract Our studies suggest that in experimental animals, submitted to a hypocaloric diet, the intrarectal administration of hCG (Human Chorionic Gonadotropin) decreases body fat and increases lean mass content relative values greater extent control animals who did not receive hCG.
3113 Background: Peg-Neutropine, GEMA BIOTECH SAU biosimilar Peg-Filgrastim, is the first Peg-Filgrastim approved in LATAM for prevention of febrile neutropenia patients treated with myelosuppressive chemotherapy. Methods: Study population: women stage 2, 3 or 4 breast cancer scheduled to receive 6 cycles chemotherapy (with Taxane) at weeks interval. Stratification was based on stage. drug administered subcutaneously a mg dose. The study blind assessors. primary endpoint Duration Severe...