A5061303897- Health Systems, Economic Evaluations, Quality of Life
- Gamma-ray bursts and supernovae
- Healthcare cost, quality, practices
- Meta-analysis and systematic reviews
- Ethics in Clinical Research
- Particle Detector Development and Performance
- Primary Care and Health Outcomes
- Nuclear Physics and Applications
- Mental Health and Patient Involvement
- Health Policy Implementation Science
- Astrophysics and Cosmic Phenomena
- Astro and Planetary Science
- Solar and Space Plasma Dynamics
- Planetary Science and Exploration
- Health and Medical Research Impacts
- Dark Matter and Cosmic Phenomena
- Healthcare Policy and Management
- Astrophysical Phenomena and Observations
- Space Science and Extraterrestrial Life
- Spaceflight effects on biology
- Animal testing and alternatives
- Geomagnetism and Paleomagnetism Studies
- Space Exploration and Technology
- Calibration and Measurement Techniques
- Distributed and Parallel Computing Systems
University of Southampton
2000-2022
NIHR Evaluation Trials and Studies Coordinating Centre
2017-2020
National Institute for Health Research
2014-2020
Wessex Institute of Technology
2012-2020
Queen's University Belfast
2018-2019
University of St Andrews
2018-2019
University of Liverpool
2018-2019
Nottingham University Hospitals NHS Trust
2018-2019
University of Lausanne
2018-2019
University of York
2018-2019
Abstract The evidence base available to trialists support trial process decisions—e.g. how best recruit and retain participants, collect data or share the results with participants—is thin. One way fill gaps in is run Studies Within A Trial, SWATs. These are self-contained research studies embedded within a host that aim evaluate explore alternative ways of delivering organising particular process. SWATs increasingly being supported by funders considered trialists, especially UK Ireland. At...
Orbiting X-ray and gamma ray instruments are subject to large background count rates due local particle fluxes in the space environment. The ability of an instrument make calibrated measurements flux from a source interest is highly dependent on accurately determining level. We present here method calculating energy for any point complete data set recorded by Burst Transient Source Experiment (BATSE) its nine year mission. BATSE Mass Model (BAMM) uses Monte Carlo mass modelling approach...
The BATSE mission aboard CGRO monitored the whole sky in 20 keV-1 MeV energy band continuously from April 1991 until June 2000. Although had very poor intrinsic angular resolution, data can be used to survey entire soft gamma-ray with < resolution and ~mCrab sensitivity by using Earth occultation method. This method determines flux measuring step count rate profile each detector as a source rises above or sets below Earth's limb. A maximum likelihood imaging technique then build up all-sky...
Abstract Objective The project aims to build a framework for conducting clinical trials long‐term interplanetary missions contribute innovation in on Earth, especially around patient involvement and ownership. Methods We conducted two workshops which participants were immersed the speculative scenario of an mission health problems emerged that required medical resolve. used virtual reality live simulation mimic zero‐gravity environment visual perception shifts followed by group discussion....
Abstract The evidence base available to trialists support trial process decisions– e.g. how best recruit and retain participants, collect data or share the results with participants – is thin. One way fill gaps in run Studies Within A Trial, SWATs. These are self-contained research studies embedded within a host that aim evaluate explore alternative ways of delivering organising particular process. SWATs increasingly being supported by funders considered trialists, especially UK Ireland. At...
<ns4:p><ns4:bold>Background: </ns4:bold>When health-related research funding agencies choose to fund research, they balance a number of competing issues: costs, stakeholder views and potential benefits. The REWARD Alliance, the related Lancet-REWARD Campaign, question whether those decisions are yielding all value could. </ns4:p><ns4:p> <ns4:bold>Methods:</ns4:bold><ns4:italic> </ns4:italic>A group agencies, organisations that represent inform set health-related-research policy from around...
<ns3:p><ns3:bold>Background:</ns3:bold> When health-related research funding agencies choose to fund research, they balance a number of competing issues: costs, stakeholder views and potential benefits. The REWARD Alliance, the related Lancet-REWARD Campaign, question whether those decisions are yielding all value could. <ns3:bold>Methods:</ns3:bold> A group agencies, organisations that represent inform set health-related-research policy from around world have come together since 2016 share,...
Recent and forthcoming studies relevant to the main performance requirements of clinical commissioning groups are highlighted. These derived from strategic approach applied health management subjects adopted in National Institute for Health Research programmes. Their mid-term perspective helps ensure sound empirical findings utility over time across organisational policy changes. A practical guide is offered identifying evidence transferable learning, with some exemplar illustrations past...
Purpose This report aims to examine the capacity for research support integrated care developments. The focus is on health service agencies in English universities. It designed promote an understanding of alternative approaches as national programmes offer new opportunities larger and more rigorous studies. Design/methodology/approach approach draws three analyses different data from relevant National Institute Health Research (NIHR) over a 30 month period. are derived commissioning briefs,...
Abstract The evidence base available to trialists support trial process decisions– e.g. how best recruit and retain participants, collect data or share the results with participants – is thin. One way fill gaps in run Studies Within A Trial, SWATs. These are self-contained research studies embedded within a host that aim evaluate explore alternative ways of delivering organising particular process. SWATs increasingly being supported by funders considered trialists, especially UK Ireland. At...
The Burst and Transient Source Experiment (BATSE) aboard CGRO monitored the whole sky through 8 NaI(Tl) crystal scintillators sensitive in 20 keV - 2 MeV energy band continuously from April 1991 until June 2000. Results are presented on long term variabilty observed brightest Active Galactic Nuclei (AGN) present BATSE data archive. This was achieved application of Earth Occultation technique to flat-fielded using Mass Model. Removal temporal background variations should allow a more...
The BATSE mission aboard CGRO observed the whole sky for 9 years in 20 keV - 2 MeV energy band. Flat-fielding of temporal variations background present data set has been accomplished through a GEANT3 Monte-Carlo simulation Mass Model (BAMM). Earth Occultation technique (EOT) is used together with maximum-likelihood imaging approach to construct all-sky maps ~mCrab sensitivity. Additionally, non-linear CLEAN algorithm applied remove large artefacts that are systematic EOT. latest survey...
The BATSE mission aboard CGRO can be used to observe hard X-ray sources by using the Earth occultation method. This method relies on measuring a step in count rate profile each detector as source rises above or sets below Earth's limb. A major problem determining sizes (and hence flux) is extracting steps from varying background. technique for flat-fielding response of gamma ray detectors has been developed at Southampton. uses dynamic Monte-Carlo model simulate dominant components gamma-ray...