A5077450195- Dermatology and Skin Diseases
- Psoriasis: Treatment and Pathogenesis
- Autoimmune Bullous Skin Diseases
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Sepsis Diagnosis and Treatment
- Urticaria and Related Conditions
- Dermatological and Skeletal Disorders
- Contact Dermatitis and Allergies
- Inflammation biomarkers and pathways
- Cancer Immunotherapy and Biomarkers
- Immune Cell Function and Interaction
- Mast cells and histamine
- Adipokines, Inflammation, and Metabolic Diseases
- T-cell and B-cell Immunology
Union Hospital
2024
Zhongshan Hospital of Xiamen University
2022-2024
Guangzhou Institute of Dermatology
2024
Fudan University
2022-2024
Zhongshan Hospital
2023
Aims To investigate levels of 25-hydroxyvitamin-D (25HVD), interleukin-17 (IL-17), IL-27, IL-35, and transforming growth factor β1 (TGF-β1) in chronic spontaneous urticaria (CSU) patients their correlations with disease activity. Methods An observational, case-control study was conducted. Eighty-one CSU fifty-eight healthy individuals were recruited into two groups. Serum 25HVD, IL-17, TGF-β1 determined via enzyme-linked immunosorbent assay (ELISA). Disease activity assessed using score...
Key Clinical Message Coronavirus disease 2019 (COVID‐19) is known to trigger systemic inflammation and elicit immune responses, which may disrupt the delicate balance of cytokines involved in psoriatic regulation. Compared other therapies dermatology, biologics used for immune‐mediated dermatological diseases have been more extensively studied during COVID‐19 pandemic. Herein, we report a case flare‐up previously well‐controlled psoriasis shortly after infection with COVID‐19, treatment...
The γδ T cells are a subpopulation of that abundantly found in the skin and mucous membranes. Their reactivity to self-antigens ability secrete various cytokines make them key component psoriasis development. Although correlation between immune repertoire (IR) T-cell receptors occurrence severity remains incompletely explored, high-throughput sequencing has led deeper understanding IR psoriasis. This study investigated differences patients with healthy controls. were identified via...
Abstract Penicillamine is a chelator that has been used in Wilson's disease, cystinuria, rheumatoid arthritis and heavy metal intoxication. We report case of 31‐year‐old man presented with skin atrophy, purpura milia on the hips shoulders after taking penicillamine for 1.5 years. According to literature review, this type penicillamine‐associated cutaneous adverse effect belongs degenerative dermopathy, which mostly occurs bony prominences points pressure patients disease or cystinuria....
Transition from secukinumab to adalimumab in COVID-19-Induced psoriasis flare-up treatment: a case reportAbstract: Coronavirus disease 2019 (COVID-19) is known trigger systemic inflammation and elicit immune responses, which may disrupt the delicate balance of cytokines involved psoriatic regulation. Compared other therapies dermatology, biologics used for immune-mediated dermatological diseases have been more extensively studied during COVID-19 pandemic. Herein, we report previously...