A5059818752- Mast cells and histamine
- Ferroptosis and cancer prognosis
- Phytochemicals and Antioxidant Activities
- Listeria monocytogenes in Food Safety
- Identification and Quantification in Food
- Memory and Neural Mechanisms
- Inflammatory mediators and NSAID effects
- SARS-CoV-2 and COVID-19 Research
- Biological Activity of Diterpenoids and Biflavonoids
- Viral gastroenteritis research and epidemiology
- Pomegranate: compositions and health benefits
- Neurotransmitter Receptor Influence on Behavior
- Epigenetics and DNA Methylation
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Medicinal plant effects and applications
- Asthma and respiratory diseases
- Olfactory and Sensory Function Studies
- Chronic Myeloid Leukemia Treatments
- Immunotherapy and Immune Responses
- Cancer Immunotherapy and Biomarkers
- Immune Cell Function and Interaction
- Cancer Mechanisms and Therapy
- Viral Infections and Immunology Research
- Radiation Effects and Dosimetry
- Click Chemistry and Applications
King Abdulaziz University
2022-2024
Taif University
2020
University of Sheffield
2012-2017
The objective of the current study was to evaluate potential Punica granatum L peel in mice as an antidiarrheal and antidiabetic agent. In study, different doses (50, 100, 150, 200 mg/kg) methanolic pomegranate extract (PPE) were administrated castor oil-induced (1 mL/kg) diarrheal mice. Mice administered loperamide hydrochloride (3 treated a baseline group. During experiment, electrolyte hematological levels analyzed, at end, histopathology intestine performed. For activity, PPE metformin...
The severe acute respiratory syndrome coronavirus 2, also known as SARS-CoV-2, is the causative agent of COVID-19 global pandemic. SARS-CoV-2 has a highly conserved non-structural protein 12 (NSP-12) involved in RNA-dependent RNA polymerase (RdRp) activity. For identification potential inhibitors for NSP-12, computational approaches such homologous proteins that have been previously targeted by FDA-approved antivirals can be employed. Herein, NSP-12 were retrieved from Protein DataBank (PDB)...
Fish is an excellent source of protein and other essential minerals vitamins; nevertheless, several food-borne disease outbreaks have been linked to the consumption different types fish. Therefore, we aimed overcome these health threats by evaluating gamma radiation as a good fish preservation method. The aerobic plate count (APC), identification most common pathogenic bacteria, organoleptic properties, proximate composition, chemical evaluations were detected in both untreated gamma-treated...
Natural antioxidants derived from plants have played a vital role in preventing wide range of human chronic conditions and provide novel bioactive leads for investigators pharmacotherapy discovery. This work was designed to examine the ethnopharmacological Urtica dioica (UD), Capsella bursa-pastoris (CBP), Inula racemosa (IR). The total phenolic flavonoid contents (TPC TFC) were illustrated through colorimetric assays, while antioxidant activity investigated DPPH ABTS assays. evaluation...
Stem cell factor (SCF) is a growth that involved in mast differentiation and proliferation. SCF primes human lung cells for enhanced responses to IgE-directed activation but not generally recognized as direct activator. mediates its effects through c-kit.The aim of this study was reappraise the on cells.Mast were isolated from lung. Mast challenged with anti-IgE or generation histamine, cysteinyl-leukotrienes (cys-LTs) prostaglandin D(2) (PGD(2) ) assessed expression marker, CD63. The c-kit...
Abstract Drugs of abuse represent a growing public health crisis. Accumulating evidence indicates that gabapentin (GBP), prescription drug, is prone to misuse, abuse, withdrawal, and dependence. Commonly, drugs modulate the dopaminergic system induce addiction. In this study, we used conditioned place preference (CPP) model investigate involvement dopamine 1 (D1) receptor on reward reinforcement behavior GBP. Under CPP paradigm, male BALB/c mice were intraperitoneally injected either saline...
Being a checkpoint, the expression level of V-set immunoregulatory receptor (VSIR) serves as an indicator extent immunosuppression. Our objective was to undertake pan-cancer analysis examine expression, genetic alterations, prognosis, and immunologic features associated with VSIR.