Li Dong

ORCID: 0000-0003-3879-8954
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About
Contact & Profiles
Research Areas
  • Glaucoma and retinal disorders
  • Magnesium Alloys: Properties and Applications
  • Corrosion Behavior and Inhibition
  • Ophthalmology and Eye Disorders
  • Cerebral Venous Sinus Thrombosis
  • Viral gastroenteritis research and epidemiology
  • Respiratory viral infections research
  • Hydrogen Storage and Materials
  • Viral Infections and Immunology Research
  • COVID-19 Clinical Research Studies
  • Immune Cell Function and Interaction
  • Long-Term Effects of COVID-19

Harbin Medical University
2023-2025

Fourth Affiliated Hospital of Harbin Medical University
2023-2025

Capital Medical University
2021-2022

Beijing Tongren Hospital
2021-2022

Wuhan University
2022

Renmin Hospital of Wuhan University
2022

Tsinghua University
2021

The cell-mediated protective and pathogenic immune responses to SARS-CoV-2 infection remain largely elusive. Here we identified 76 distinct cell subsets in the PBMC samples that were associated with various clinical presentations of COVID-19 using scRNA-seq technology coupled a deep comprehensive analysis unique surface markers differentially expressed genes. We revealed (TRAV1-2 + CD8 )MAIT cells (NCAM1 hi CD160 )NK significantly enriched asymptomatic subjects whereas (LAG3 )NKT increased...

10.3389/fimmu.2022.812514 article EN cc-by Frontiers in Immunology 2022-02-22

Due to their biocompatibility, biodegradability, and suitable mechanical properties, magnesium-based biodegradable implants are emerging as a promising alternative traditional metal implants. The Mg-4Y-3RE (WE43) alloy is among the most extensively studied widely utilized magnesium alloys in clinical applications. As an absorbable degradable metallic material, undergo gradual degradation, wear, fracture within body. These reduce long-term risks associated with permanent but generate...

10.1021/acsomega.4c09349 article EN cc-by-nc-nd ACS Omega 2025-04-25

Magnesium alloys have been used to manufacture biodegradable implants, bone graft substitutes, and cardiovascular stents. WE43 was the most widely magnesium alloy. The degradation process begins when alloy stent is implanted in body comes into contact with fluid. products include hydrogen, Mg2+ , local alkaline environment, unsoluble products. A large number of studies focused on pH vitro, vivo alloys, but few corrosion (UCPs). In this study, UCPs were prepared by immersion their effects...

10.1002/jbm.a.37601 article EN Journal of Biomedical Materials Research Part A 2023-09-08

Environmental surveillance (ES) is a useful approach for monitoring circulating viruses, including polioviruses (PVs) and non-polio enteroviruses (NPEVs). In this study, the results of nine years ES from 2013 to 2021 at six sampling sites in three cities Fujian Province, China, were summarized. It showed that sewage samples contained abundant but positive rate was affected by different sites. From 520 samples, 431 PVs, 1,713 NPEVs, 281 human adenoviruses (HAdVs) isolated. PV isolates had...

10.1016/j.bsheal.2023.05.003 article EN cc-by-nc-nd Biosafety and Health 2023-05-12

The aim of this study is to establish a random forest model detect active and quiescent phases patients with Graves Orbitopathy (GO).A total 243 (486 eyes) diagnosed GO in Beijing TongRen hospital were included the study. Clinical Activity Score was regarded as golden standard, whereas sex, age, smoking status, radioactive I131 treatment history, thyroid nodules, thyromegaly, hormone, Thyroid-stimulating hormone receptor antibodies chosen predictive characteristic variables model....

10.1097/scs.0000000000008946 article EN Journal of Craniofacial Surgery 2022-08-23

Abstract Objective: The aim of this study is to establish a random forest model detect active and quiescent phases patients with Thyroid-associated ophthalmopathy (TAO) evaluate its diagnostic performance. Methods: A total 146 (292 eyes) who were diagnosed TAO treated in the Ophthalmology Outpatient Clinic Beijing TongRen hospital retrospectively included study. We took clinical activity score as target; gender, age, smoking status, I-131 treatment history, thyroid nodules, thyromegaly,...

10.21203/rs.3.rs-787674/v1 preprint EN cc-by Research Square (Research Square) 2021-09-14
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