- Skin Protection and Aging
- Dermatologic Treatments and Research
- Facial Rejuvenation and Surgery Techniques
- Advancements in Transdermal Drug Delivery
- Contact Dermatitis and Allergies
- Botulinum Toxin and Related Neurological Disorders
- Hair Growth and Disorders
- Dermatology and Skin Diseases
- melanin and skin pigmentation
- Body Contouring and Surgery
- Cutaneous Melanoma Detection and Management
- Nail Diseases and Treatments
- Thermoregulation and physiological responses
- Acne and Rosacea Treatments and Effects
- Textile materials and evaluations
- Cancer and Skin Lesions
- Nonmelanoma Skin Cancer Studies
- Sympathectomy and Hyperhidrosis Treatments
- Olfactory and Sensory Function Studies
- Liquid Crystal Research Advancements
- Body Image and Dysmorphia Studies
- Bee Products Chemical Analysis
- Diagnosis and Treatment of Venous Diseases
- Plant Surface Properties and Treatments
- Circadian rhythm and melatonin
Centre Hospitalier Universitaire de Besançon
2014-2021
Tehran University of Medical Sciences
2012-2021
Inserm
2014-2021
Physician’s Hair Institute
2021
Ahvaz Jundishapur University of Medical Sciences
2021
University of Rochester
2021
Clinical Investigation Center Plurithematic Tours
2013-2021
Université de franche-comté
2013-2018
Hôpital Saint-Jacques
2015
Research and Studies Telecommunications Centre
2015
Background . Understanding the physiological, chemical, and biophysical characteristics of skin helps us to arrange a proper approach management diseases. Objective The aim this study was measure 6 normal (sebum content, hydration, transepidermal water loss (TEWL), erythema index, melanin elasticity) in population assess effect sex, age, body location on them. Methods Fifty healthy volunteers 5 age groups (5 males females each) were enrolled study. A multifunctional physiology monitor...
Background The more recent use of ultrasound scanning allows a direct measurement on unmodified skin, and is considered to be reliable method for in vivo epidermal dermal thickness. objective this study was assess the influence gender age thickness echo‐density skin measured by high frequency ultrasonography ( HFUS ). Materials methods This carried out 30 healthy volunteers (17 female, 13 male) with range 24–61 years old. dermis as well entrance echo five anatomic sites (cheek, neck, palm,...
Introduction High frequency ultrasonography ( HFUS ) is a non‐invasive, low risk method which can provide real‐time visual information regarding different processes in cutaneous tissue. The goal of this study to compare the accuracy determining depth and width basal cell carcinoma BCC lesions compared with histopathology as reference standard. Methods 56 primary s various locations were measured vivo using ultrasound system device Digital Taberna Promedica (Luneburg, FRG DUB 20 Ultrasound...
Background NCTF®135HA is a bio-revitalizing solution containing hyaluronic acid designed to compensate for skin dehydration, fatigue, and fine wrinkles associated with endogenous environmental aging.Methods We conducted randomized, active-controlled study evaluate the efficacy tolerability of injections on face (crow's feet), neck, décolleté regions. Subjects were randomly assigned (3:1) receive three treatment sessions plus twice-daily anti-aging moisturizer cream or alone (control). The...
ABSTRACT Objective NCTF135HA, a versatile polyrevitalizing solution, is potent agent for enhancing skin quality, radiance, moisture, vitality, and diminishing fine wrinkles caused by aging factors. Data demonstrate divergence in its application from quality enhancement to treatment of vitiligo lesions. To know more precisely about the protocol use among providers, alone or combination with other procedures, we performed an international survey. Method A Steering Committee dermatologists,...
Interventions to enhance lip volume and shape are common aesthetic procedures counter signs of aging. This study aimed assess the efficacy Art Filler Lips (AFL), with or without retouching, at restoring volume, tolerability, persistence over 18 months. During this open-label study, AFL (≤2.0 mL) was injected into upper, lower, and/or both red lips borders baseline (D0). Patients were evaluated D21, when, if necessary, retouching performed. D42, D90, D180, D270, D360, D450, D540. The primary...
Summary Background Sensitive skin is frequently complaint in dermatology consultation with cutaneous manifestations such as stinging, redness, dryness, and burning sensation that affect the quality of life. Its pathogenesis mainly related to dysfunction neurosensory, barrier, also immune activity. The treatment generally based on continuous topical therapy by nonirritating complex. Objective To evaluate antisensitive function a new complex cream composed Yunnan Portulaca oleracea extract,...
Background: Several studies have confirmed dramatic changes in skin surface parameters during the winter months. Although there are many supporting positive effects of topical treatment, no published demonstrating oral supplementation prevention negative winter. The purpose this study was to evaluate efficacy an micronutrient supplement preventing weather on quality using noninvasive biometrologic instruments. Methods: This included 80 healthy female volunteers aged 35–55 years with...
<b>Background:</b> The exposure of skin to ultraviolet radiation and temperature differs significantly during the day. It is reasonable that biophysical parameters human have periodic daily fluctuation. objective this study was fluctuations various characteristics Middle Eastern in standardized experimental conditions. <b>Materials</b> <b>and Methods:</b> Seven including stratum corneum hydration, transepidermal water loss, pH, sebum, elasticity, color, erythema index were measured at three...
Abstract Background Age‐related changes of facial soft tissue cause clinical signs aging such as lip atrophy, marionette lines, and an accentuated nasolabial fold. These can be modified using dermal fillers. Aims To evaluate efficacy, longevity, safety a cross‐linked hyaluronic acid‐based filler with Tri‐Hyal technology in the treatment lips, folds, lines. Materials Methods This prospective, multi‐center trial evaluated injections three different areas (lips, fold alone, or wrinkles)...
ABSTRACT Background Skin biorevitalization involves multiple intradermal injections to enhance skin quality, but precise dermal targeting can be challenging due variations in thickness smaller, less painful needles with fewer reactions are attractive options. Aims This study evaluates a new Micro‐Needle device's performance and safety comparison the classic needle used biorevitalization. Patients/Methods Subjects facial neck aging were enrolled. Safety outcomes, including immediate local...
Abstract Background Bateman purpura is characterized by diffuse senile skin atrophy, and spontaneous stellar pseudocicatrices. Cutaneous changes in the course of ageing have been related to lower levels ascorbic acid into dermis elderly people. Objective In this study, we postulate that could be linked dermal vitamin C deficiency corrected topical administration vitamin. Methods A 12‐weeks, hemi‐member (forearm or leg), randomized double‐blind comparative study was conducted 18 patients with...
Abstract The beneficial role of subcutaneous adipose tissue in skin rejuvenation derived from its capacity to fill the under‐layer volumes but also ability regulate extracellular matrix production by dermis fibroblasts. Hyaluronic acid (HA), a major component matrix, is commonly used injectable dermal filler showing excellent efficiencies maintain augmentation even after biodegradation. To improve their stability, HA molecules can be “cross‐linked” each other. effects cross‐linked HA‐based...
Botulinum neurotoxin type A (BTX-A) injection is the treatment of choice for idiopathic axillary hyperhidrosis (IAH) refractory to conventional treatments.This study compared efficacy BTX-A and iontophoresis IAH in a randomized controlled trial.In eleven patients with diagnosis IAH, one axilla was randomly treated injections 1.5 mL (250 MU) BTX-A, other side administered by iontophoresis. The amount sweating, skin hydration, transepidermal water loss, pain, patient satisfaction on both were...
Abstract Background Hyaluronic acid‐based fillers have an immediate volumizing effect for the treatment of dermal contour deformities and to smooth depressions formed by loss volume. A previous study on 2016–2018 has shown efficacy safety HA‐based filler ART FILLER® Volume midface only, but not in a comparative manner. Methods In this context, 18 months prospective randomized single‐blind non‐inferiority versus reference product Juvéderm Voluma® was performed midface, temple, jawline,...
Mécano-Stimulation™ of the skin improves sagging score and induces beneficial functional modification fibroblasts: clinical, biological, histological evaluations Philippe Humbert,1,2 Ferial Fanian,1,2 Thomas Lihoreau,1,2 Adeline Jeudy,1,2 Ahmed Elkhyat,1,2 Sophie Robin,3 Carol Courderot-Masuyer,3 Hélène Tauzin,3 Christine Lafforgue,1,2,4 Marek Haftek5 1Research Studies Center on Integument (CERT), Department Dermatology, Clinical Investigation (CIC 1431),...
Introduction: Skin aging is the result of many cellular dysfunctions over time particularly fibroblasts and keratinocytes. These could be decelerated by preventive effects some skin treatments such as Intradermal injections. NCTF 135HA has a polycomponent formulation designed to improve efficacy non-cross linked hyaluronic acid (as micro-filler) on function. Although been used aesthetic practitioners since 20 years, we have analyzed all in vitro, ex vivo studies during past 10 years order...