A5060424193- Chronic Obstructive Pulmonary Disease (COPD) Research
- Epilepsy research and treatment
- Cystic Fibrosis Research Advances
- Fetal and Pediatric Neurological Disorders
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lung Cancer Diagnosis and Treatment
- Genetics and Neurodevelopmental Disorders
- Ultrasound in Clinical Applications
- Neonatal and fetal brain pathology
- Infectious Diseases and Tuberculosis
- Orthopedic Surgery and Rehabilitation
- Gastrointestinal disorders and treatments
- Neonatal Respiratory Health Research
- Myasthenia Gravis and Thymoma
- COVID-19 diagnosis using AI
- Respiratory Support and Mechanisms
- Medical Imaging and Pathology Studies
- Inhalation and Respiratory Drug Delivery
- Functional Brain Connectivity Studies
- Glioma Diagnosis and Treatment
- Dysphagia Assessment and Management
- Neuroblastoma Research and Treatments
- Tuberculosis Research and Epidemiology
- EEG and Brain-Computer Interfaces
- Meningioma and schwannoma management
Istituti di Ricovero e Cura a Carattere Scientifico
2023-2024
Meyer Children's Hospital
2021-2024
Meyer Children's Hospital
2023
University of Florence
2011-2022
Azienda Ospedaliero-Universitaria Careggi
2019
Pulmonary infection with SARS-CoV-2 virus (severe acute respiratory syndrome coronavirus 2; COVID-19) has rapidly spread worldwide to become a global pandemic.To collect paediatric COVID-19 cases and summarize both clinical imaging findings in children who tested positive on polymerase chain reaction testing for SARS-CoV-2.Data were collected by completion of standardised case report form submitted the office European Society Paediatric Radiology from March 12 April 8, 2020. Chest younger...
The SLC35A2 gene, located at chromosome Xp11.23, encodes for a uridine diphosphate-galactose transporter. We describe clinical, genetic, neuroimaging, EEG, and histopathologic findings assess possible predictors of postoperative seizure cognitive outcome in 47 patients with refractory epilepsy brain somatic gene variants.This is retrospective multicenter study where we performed descriptive analysis classical hypothesis testing. included the variables interest significantly associated...
Myxoid glioneuronal tumor (MGT) is a benign neoplasm recently introduced in the World Health Organization (WHO) classification of central nervous system (CNS) tumors. MGTs are typically located septum pellucidum, foramen Monro or periventricular white matter lateral ventricle. They were previously diagnosed as dysembryoplastic neuroepithelial tumors (DNT), showing histological features almost indistinguishable from classical cortical DNT. Despite that, have been associated with specific...
Protocadherin-19 (PCDH19) developmental and epileptic encephalopathy causes an early-onset epilepsy syndrome with limbic seizures, typically occurring in clusters variably associated intellectual disability a range of psychiatric disorders including hyperactive, obsessive-compulsive autistic features. Previous quantitative neuroimaging studies revealed abnormal cortical areas the formation (parahippocampal fusiform gyri) underlying white-matter fibers. In this study, we adopted morphometric,...
Mutations of the voltage-gated sodium channel SCN1A gene (MIM#182389) are among most clinically relevant epilepsy-related genetic mutations and present variable phenotypes, from milder epilepsy with febrile seizures plus to Dravet syndrome, a severe developmental epileptic encephalopathy. Qualitative neuroimaging studies have identified malformations cortical development in some patients mild atrophic changes, partially confirmed by quantitative studies. Precise correlations between MRI...
This is a prospective, observational study involving three Cystic Fibrosis (CF) adult patients, evaluating the changes in chest magnetic resonance imaging (MRI) months after start of elexacaftor/tezacaftor and ivacaftor therapy. MRI showed drastic reduction mucus plugging bronchial wall thickening, with an improvement diffusion-weighted score. Similarly, marked spirometric parameters, nutritional status, sweat chloride was observed. Our preliminary data confirm that could be useful tool to...
To evaluate with a volume-corrected whole-lung approach changes in lung density over 2 years consistent progression of pulmonary emphysema smokers and former enrolled the ITALUNG trial cancer screening using low-dose computed tomography (LDCT).A total 103 subjects (mean age 63±4 y pack-year history at least 20) underwent LDCT examinations apart. Visual assessment was made independently by experienced observers on initial examination 0 to 4 grading system for each 6 regions (right left upper,...
Lung disease in cystic fibrosis (CF) is characterized by reduced mucociliary clearance, airway plugging, recurrent infections and chronic pulmonary inflammation. Patients who are affected undergo daily respiratory physiotherapy to improve clearance. Intrapulmonary percussive ventilation (IPV) a technique used clinical practice, but it not commonly CF patients. Evidence various pathologies, particularly children, still lacking. We present the case of an eleven-year-old boy with did respond...
Abstract Protocadherin-19 ( PCDH19 ) developmental and epileptic encephalopathy causes an early-onset epilepsy syndrome with limbic seizures, typically occurring in clusters variably associated intellectual disability a range of psychiatric disorders including hyperactive, obsessive-compulsive autistic features. Previous quantitative neuroimaging studies revealed abnormal cortical areas the formation (parahippocampal fusiform gyri) underlying white-matter fibers. In this study, we adopted...
The collection of chylous in the pleural space is defined chylothorax and it represents a potentially life-threatening disorder cause morbidity prolonged hospitalization. It must be promptly identified to avoid risk respiratory insufficiency immunodeficiency. Chylothorax very rare complication surgery neck chest trauma does generally occur hours or days after exposure aforementioned surgery. We present case 5-year-old child with severe symptoms, which appeared during COVID-19 pandemic April...