Gan Zhan

ORCID: 0000-0003-3933-2937
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About
Contact & Profiles
Research Areas
  • Radiomics and Machine Learning in Medical Imaging
  • AI in cancer detection
  • Colorectal Cancer Screening and Detection
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Medical Image Segmentation Techniques
  • Infrared Thermography in Medicine
  • MRI in cancer diagnosis
  • Single-cell and spatial transcriptomics
  • Medical Imaging and Analysis
  • Advanced Image Processing Techniques
  • Cancer-related molecular mechanisms research
  • Generative Adversarial Networks and Image Synthesis

Ritsumeikan University
2023-2024

Accurate preoperative prediction of microvascular invasion (MVI) and recurrence-free survival (RFS) is vital for personalised hepatocellular carcinoma (HCC) management. We developed a multitask deep learning model to predict MVI RFS using MRI scans.

10.1111/liv.15870 article EN Liver International 2024-03-04

Post-operative early recurrence (ER) of hepatocellular carcinoma (HCC) is a major cause mortality. Predicting ER before treatment can guide and follow-up protocols. Deep learning frameworks, known for their superior performance, are widely used in medical imaging. However, they face challenges due to limited annotated data. We propose multi-task pre-training method using self-supervised with images predicting the HCC. This involves two pretext tasks: phase shuffle, focusing on intra-image...

10.3390/info15080493 article EN cc-by Information 2024-08-17

Contrast-enhanced computed tomography (CE-CT) images are vital for clinical diagnosis of focal liver lesions (FLLs). However, the use CE-CT imposes a significant burden on patients due to injection contrast agents and extended shooting. Deep learning-based image synthesis models offer promising solution that synthesizes from non-contrasted CT (NC-CT) images. Unlike natural images, medical requires specific focus certain organs or localized regions ensure accurate diagnosis. Determining how...

10.1088/2057-1976/ad31fa article EN Biomedical Physics & Engineering Express 2024-03-08

Spatial transcriptomics (ST) offers insights into gene expression patterns within tumor microenvironments, but its widespread application is impeded by cost constraints. To address this, predicting ST from Histology emerges as a cost-effective alternative. However, current methods such STNet, HistoGene, and Hist2ST exhibit limitations, either overlooking stain variation across datasets or failing to well explore inter-spot correlations in scenarios with limited Whole Slide Image (WSI) data....

10.1109/embc53108.2024.10782295 article EN 2024-07-15

Hepatocellular carcinoma (HCC) is a representative primary liver cancer with high incidence and mortality. Surgical resection the first option of treatment, but patients are usually at risk tumor recurrence within 2 years, resulting in poor overall outcomes. Thus, it great clinical significance to predict HCC early improve survival rate. Existing transformer-based methods typically rely on models pretrained ImageNet, which may not effectively extract features from medical images. we propose...

10.1109/gcce59613.2023.10315652 article EN 2022 IEEE 11th Global Conference on Consumer Electronics (GCCE) 2023-10-10
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