A5055106247- Analytical Chemistry and Sensors
- Advanced biosensing and bioanalysis techniques
- Electrochemical Analysis and Applications
- Electrochemical sensors and biosensors
- Bone Tissue Engineering Materials
- Ultrasound and Hyperthermia Applications
- Alzheimer's disease research and treatments
- Microfluidic and Bio-sensing Technologies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Biosensors and Analytical Detection
- Nanoparticle-Based Drug Delivery
- Neuroscience and Neural Engineering
- Photoreceptor and optogenetics research
- 3D Printing in Biomedical Research
- Monoclonal and Polyclonal Antibodies Research
- RNA Interference and Gene Delivery
- Muscle Physiology and Disorders
- Nanoplatforms for cancer theranostics
- Dysphagia Assessment and Management
- EEG and Brain-Computer Interfaces
- Molecular Junctions and Nanostructures
- Advanced Biosensing Techniques and Applications
- Muscle activation and electromyography studies
- Ultrasound and Cavitation Phenomena
- Graphene and Nanomaterials Applications
National Yang Ming Chiao Tung University
2015-2024
Institute of Biomedical Science
2015-2019
National Chiayi University
2016
National Cheng Kung University
2012-2013
National Taiwan University
2010-2012
National Science and Technology Council
2010
Kyoto University
2010
The culture environment plays an important role for stem cells’ cultivation. Static or dynamic preserve differential potentials to affect human mesenchymal (hMSCs) proliferation and differentiation. In this study, hMSCs were seeded on fiber disks cultured in a bidirectional-flow bioreactor spinner-flask with supplement of osteogenic medium. hMSCs’ proliferation, differentiation, extracellular matrix deposition mineralization demonstrated. results showed that the spinner flask improved cell...
As the occurrence of Alzheimer's disease (AD) has increased, detection and treatment AD have become global social issues. Effective early wide-range screening allow patients to gain control delay brain degeneration. For these reasons, we choose electrochemical sensors complete task. Although bio-electrochemical technology for antibody antigen sensing is not a new technology, considering scarcity tear samples dementia since existing techniques are highly invasive expensive subjects, use...
Gram-negative bacteria (GNBs) are common pathogens causing severe sepsis. Rapid evaluation of drug susceptibility would guide effective antibiotic treatment and promote life-saving. A total 78 clinical isolates 13 species collected between April 2013 November from two medical centers in Tainan were tested. Bacterial morphology changes different concentrations antibiotics observed under the electric field a quadruple electrode array using light microscopy. The minimal inhibitory (MICs) four...
Developing an effective vehicle for cancer treatment, hydroxyapatite nanoparticles were fabricated drug delivery. When 5-Fluorouracil, a major chemoagent, is combined with nanocarriers by interclay insertion, the modified have superior lysosomal degradation profiles, which could be leveraged as controlled release. The decomposition of facilitates release 5-Fluorouracil into cytoplasm causing cell death. Hydroxyapatite with/without synthesized and analyzed in this study. Their crystallization...
Heavy metals are very harmful to the environment and is toxic which affects human health. Monitoring heavy metal ion in food water necessary. In this research, we developed a FET based selective sensor for detecting Arsenite (As(III)) ions by hand held device. The characteristics carried out illustrated. This shows higher sensitivity (35.19 mV/log [As 3+ ]) than ideal Nernstian slope. dynamic range of from 10 −10 M −4 M. detection limit below comparable ICP-MS. captures particular target not...
To develop a safe and effective nonviral gene delivery system for transgenic chicken manipulation, we developed gelatin nanocarriers using reporter plasmid (pEGFP-C1; enhanced green fluorescence protein, EGFP) that expressed EGFP. pEGFP-C1-containing nanoparticles (GP/pEGFP) were prepared water–ethanol solvent displacement method characterized by size, surface charge, DNA loading, protection ability. For delivery, pEGFP-C1 was stably efficiently encapsulated in GPs approximately 300 nm...
We used silica–carbon hollow spheres (SCHSs) as material for thermal production under NIR laser irradiation. Concanavalin A (ConA), a lectin, was applied to enhance binding on the cell surface of liver cancer cells. demonstrated that ConA conjugated SCHSs killed cells efficiently.
The sensing properties of immunosensors are determined not only by the amount immobilized antibodies but also number effective antigen-binding sites antibody. Protein A (PA) exhibits a high degree affinity with Fc part IgG antibody to feasibly produce oriented immobilization. This work proposes simple method control PA surface density on gold nanostructure (AuNS)-deposited screen-printed carbon electrodes (SPCEs) mixing concentration-varied and bovine serum albumin (BSA), explore effect...