A5074853269- Retinal Diseases and Treatments
- Ophthalmology and Visual Impairment Studies
- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Corneal surgery and disorders
- Systemic Sclerosis and Related Diseases
- Skin Protection and Aging
- melanin and skin pigmentation
Indiana University Bloomington
2021-2025
ESIC Hospital
2024
Indiana University
2023
Manipal Academy of Higher Education
2020
SIGNIFICANCE Visual acuity (VA) depends on many factors. When the goal is to assess retinal health rather than performance, then using a 3-mm pupil reduces unwanted wavefront aberrations. The axis of astigmatism can still potentially change with age. PURPOSE VA measurements are intended quantify status retina, extraneous optical aberrations make measured worse and introduce variability, particularly in aging eyes. Our study quantifies for pupil, which similar theoretical size best VA, versus...
Purpose Cones in diabetic patients are at risk due to metabolic and vascular changes. By imaging retinal vessel modeling high magnification, we reduced its impact on cone distribution measurements. The images thickness measurements provided information about microenvironment. Methods We compared data 10 subjects (28–78 yr) our published norms from 36 younger older controls. All were consented tested a manner approved by the Indiana University Institutional Review Board, which adhered...
Purpose: To find the agreement and repeatability of Icare ic100 tonometer. Methods: We included 150 subjects above age 18 years for this cross-sectional, multicenter study with intraocular pressure (IOP) ≥7 mmHg. After initial ophthalmic examination, two masked examiners took five IOP measurements using three different instruments; ic100, TA01i, Goldmann applanation tonometer (GAT) in only one eye participants. Comparison instruments was quantified intraclass correlation coefficient (ICC)...
We demonstrate a free-space, trolley-mounted potential vision tester (PVT), designed to study and improve the accuracy of visual acuity (VA) measurements in aging eye. Key features include high-resolution display presented Maxwellian view, 3 mm pupil limit wavefront (WF) aberrations, moderate cost deformable mirror induce or correct higher order optical aberrations. The supported accurate measurement acuities down 20/5. cost, piezo induced seven nominal calibrated as 0, -0.32, -0.23, + 0.27,...
<h3>Background:</h3> Systemic sclerosis (SSc) is characterized by immune dysregulation, vasculopathy and fibrosis. Fibroproliferative in small arteries destructive capillaries are the two unique features causing tissue ischemia Monocytes/macrophages contribute to pathogenesis of SSC secreting TGF-β, a key fibrogenic cytokine. However, HDL prevents migration recruitment macrophages. According recent studies, monocyte/HDL ratio (MHR) positively correlated with markers acute inflammation,...
SIGNIFICANCE Suspected clinically significant macular edema (SCSME) from exudates differed among ethnic groups in our underserved population. African American and Asian subjects had higher prevalence than Hispanics non-Hispanic Caucasians, the same clinics. Men women. Highly elevated blood glucose was frequent associated with SCSME. PURPOSE We investigated association between presence of SCSME hemoglobin A1c (HbA1c), as well demographic factors such age, sex, group. Our population diabetic...
Abstract Purpose Visual acuity (VA) is a primary outcome measure that defines the success of clinical interventions for retinal diseases such as age‐related macular degeneration (AMD) or diabetic oedema (DME). These conditions can lead to presence subretinal fluid, causing substantial photoreceptor layer elevation. Hyperopic defocus then occurs, affecting VA measurements. In this study, we simulated induced hyperopic shift real‐world values elevation and measured effect on Methods To...