- Acne and Rosacea Treatments and Effects
- Dermatologic Treatments and Research
- Dermatology and Skin Diseases
- Psoriasis: Treatment and Pathogenesis
- Cutaneous lymphoproliferative disorders research
- Nail Diseases and Treatments
- Nonmelanoma Skin Cancer Studies
- Contact Dermatitis and Allergies
- Hair Growth and Disorders
- Hidradenitis Suppurativa and Treatments
- Dermatological and COVID-19 studies
- melanin and skin pigmentation
- Skin Diseases and Diabetes
- Pharmacological Effects of Natural Compounds
- Skin and Cellular Biology Research
- Dermatological diseases and infestations
- Autoimmune and Inflammatory Disorders
- Cutaneous Melanoma Detection and Management
- Autoimmune Bullous Skin Diseases
- Eosinophilic Disorders and Syndromes
- PI3K/AKT/mTOR signaling in cancer
- Urticaria and Related Conditions
- Inflammatory Biomarkers in Disease Prognosis
- Chemotherapy-related skin toxicity
- Mast cells and histamine
Sağlık Bilimleri Üniversitesi
2018-2025
University of Health Sciences Antigua
2020-2025
Şişli Etfal Eğitim ve Araştırma Hastanesi
2014-2024
Universidad CES
2023
University of Health Sciences
2020
Bahçeşehir University
2020
Christie's
2020
SKiN Health
2019
Ümraniye Eğitim ve Araştırma Hastanesi
2019
Austrian Society of Dermatology and Venereology
2016
Recent studies support the relation of psoriasis with obesity and cardiovascular disease. Leptin, a peptide hormone secreted predominantly from adipose tissue, is involved in regulation energy intake expenditure. Recently, it has been shown to have several immunological effects including induction proinflammatory cytokine production.To investigate possible role leptin pathogenesis.Forty-three patients psoriasis, 10 diseased healthy controls normal body mass index were included. Serum fasting...
Alopecia areata (AA) is a T cell-mediated autoimmune disease that causes inflammation around anagen-stage hair follicles. Insufficient levels of vitamin D have been implicated in variety diseases. Previous reports described the effects on follicles.To evaluate status patients with AA, and relationship between severity.A cross-sectional study 86 44 vitiligo 58 healthy controls was conducted. The serum group were determined by liquid chromatography/tandem mass spectrometry.Serum...
BACKGROUND: Androgenetic alopecia (AGA) is a patterned hair loss occurring due to systemic androgen and genetic factors. It the most common cause of in both genders. In recent years, many studies investigating relation between diseases androgenetic presented controversial results. OBJECTIVES: this study we aimed investigate frequency alopecia, presence accompanying diseases, body mass index severity association hyperandrogenemia signs with patients who referred our outpatient clinic....
Demodex mites are found on the skin of many healthy individuals. in high densities considered to play a pathogenic role.To investigate association between infestation and three most common facial dermatoses: acne vulgaris, rosacea seborrheic dermatitis.This prospective, observational case-control study included 127 patients (43 with 43 41 dermatitis) 77 controls. The presence demodicosis was evaluated by standardized surface biopsy both patient control groups.In terms gender age, no...
The authors declare no conflicts of interest. Table S1 Overall demographics and comparison demographical parameters between groups S1b: Description hand hygiene the study population in workplace daily life two S2: Multivariate analysis for identifying independent risk factors associated with eczema S3: Clinical characteristics Please note: publisher is not responsible content or functionality any supporting information supplied by authors. Any queries (other than missing content) should be...
There are only a few studies about epidemiological features of acne vulgaris in the literature. The aim this study was to analyze demographic, clinical, familial and environmental characteristics acne, role diet aggravating factors association these with severity.Patients diagnosis mild-moderate severe were consecutively interviewed at participating centers during period.A total 3826 patients 759 control involved study. Mild most common type lesions localized on face followed by trunk....
Psoriasis is a chronic immune-mediated inflammatory skin disease that associated with cardiovascular comorbidities. The objective of this retrospective study to assess the C-reactive protein, monocyte-to-high-density-lipoprotein ratio, neutrophil-to-lymphocyte platelet-to-lymphocyte and monocyte-to-lymphocyte ratio as markers in patients psoriasis search for relationship between these parameters severity, defined by area severity index. There were 94 118 healthy controls enrolled study....
Malassezia colonization, sebaceous gland activity, hormones, immune system defects, environmental factors, and the interactions between these factors are thought to contribute pathogenesis of seborrheic dermatitis (SD). Zinc, an essential element, is involved in many biological processes including ones that development SD. The aim this study evaluate serum zinc levels patients with SD.Forty-three SD 41 healthy controls were enrolled study. Disease activity was assessed by Seborrheic...
Hidradenitis suppurativa is a chronic inflammatory skin disease of terminal follicular acroinfundibulum.This study aimed to evaluate serum irisin, plasma glucose, insulin, and lipid levels in hidradenitis suppurativa, elucidate possible associations with activity, inflammatory, or metabolic parameters.This case-control included 37 patients (M/F: 9/28) sex-, age- body mass index -matched healthy controls 11/26). Demographic data, Hurley stage disease, fasting total cholesterol, high density...
Hand eczema (HE) has increased among healthcare workers (HCWs) working in coronavirus disease-2019 (COVID-19) units, and was associated with hand hygiene practices.
Currently, no generally accepted laboratory marker for monitorizing the disease activity and therapy response of psoriasis is known.The aim study to evaluate effects systemic therapies on C-reactive protein (CRP) neutrophil-lymphocyte ratio (NLR) in psoriasis.One hundred patients with treated narrow band ultraviolet B, acitretin, cyclosporine, methotrexate, adalimumab, etanercept, ustekinumab were prospectively evaluated. At baseline at week 12, CRP, NLR, Psoriasis Area Severity Index (PASI)...
Rosacea is an inflammatory skin disease with a chronic course. In the past, association between rosacea and smoking was examined only in few studies.The objective of this study to investigate prevalence influence patients.This prospective cross-sectional includes 200 patients age- gender-matched rosacea-free controls. Using National Society Expert Committee classification, we divided into three subgroups as having erythematotelangiectatic (ETR), papulopustular (PPR), phymatous (PhR)....
Abstract Background Masseter muscle hypertrophy is characterized by a symmetrical or asymmetrical increase in volume. Although it can be asymptomatic, may associated with bruxism. Therefore, patients seek intervention for esthetic and/or functional concerns. This study aimed to establish patient characteristics, purpose of undergoing botulinum toxin injection into the masseter muscles, efficacy, and side effects procedure at dermatology clinic. Methods A retrospective chart review was...
Introduction: In recent years, the role of mammalian target rapamycin (mTOR) pathway, which is one intracellular signaling pathways and known as main control pathway metabolism, in pathogenesis psoriasis has been emphasized. Objectives: We sought to investigate importance mTOR psoriasis. Methods: Forty patients with 40 healthy volunteers were included this case-control study. Serum fasting mTORC1 mTORC2 levels study groups examined by enzyme-linked immunosorbent assay. Results: significantly...
Marjolin's ulcer is an aggressive cutaneous malignancy common in previously traumatized or chronically inflamed skin.It has high regional metastasis and fatality rates.Our patient presented with subcutaneous nodules ulcerations on the right limb.He had a history of osteomyelitis fifth toe.Histopathological examination nodule ulceration demonstrated squamous cell carcinoma.The were in-transit metastases ulcer.Here, we present case carcinoma arising at site chronic resultant metastases.(Ann...
Objective: Recent studies implicate the role of inflammatory responses in chronic spontaneous urticaria (CSU). The purpose this study was to analyse levels neutrophil-lymphocyte ratio (NLR), serum C- reactive protein (CRP) and uric acid CSU patients, investigate relationship between these parameters disease activity. Material Methods: A total 100 people, consisting 50 patients healthy controls, who have no systemic disease, inflammatory, infectious or autoimmune malignancy, were included...
Recent studies that investigated the effect of vitamin D on skin cancer risk have exhibited inconsistent results.
Objective: Acne vulgaris is a disease of pilosebaceous unit. Although multiple factors contribute to the development acne, inflammation key component in pathogenesis. Creactive protein (CRP) well-known marker and there are few reports studying antioxidant, anti-inflammatory effects vitamin D acne. In present study, aim was compare serum CRP levels acne patients with control subjects. Material Methods: 65 vulgaris, 41 healthy subjects were enrolled this crosssectional study. Serum both groups...