Curtis L. Blankespoor

ORCID: 0000-0003-4002-101X
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About
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Research Areas
  • Parasite Biology and Host Interactions
  • Insect Pest Control Strategies
  • Insect and Pesticide Research
  • Insect-Plant Interactions and Control
  • Bird parasitology and diseases
  • Forest Insect Ecology and Management
  • Parasites and Host Interactions
  • Chemical Synthesis and Reactions
  • Animal Ecology and Behavior Studies
  • Wildlife Ecology and Conservation
  • Organic Chemistry Cycloaddition Reactions
  • Oxidative Organic Chemistry Reactions
  • Asymmetric Synthesis and Catalysis
  • Synthetic Organic Chemistry Methods
  • Insect Resistance and Genetics
  • Catalytic C–H Functionalization Methods
  • Allelopathy and phytotoxic interactions
  • Crystal structures of chemical compounds
  • Fish biology, ecology, and behavior
  • Chemical Synthesis and Analysis
  • Aquaculture disease management and microbiota
  • Forensic Entomology and Diptera Studies
  • Organic and Inorganic Chemical Reactions
  • Parasitic infections in humans and animals
  • Helminth infection and control

University of Michigan Biological Station
2018-2025

Jackson College
2018-2025

University of Michigan
2018-2025

Michigan United
2023-2024

Calvin University
1996-2001

Wake Forest University
1996

Cornell University
1989-1994

Hope College
1988-1990

Swimmer's itch is caused by the accidental penetration of human skin various species avian schistosomes that naturally cycle in bird and snail hosts. Little known about ontogeny their vertebrate hosts, especially wild birds. Taking advantage abundance common merganser (Mergus merganser) broods on northern Lower Peninsula lakes Michigan, we obtained fecal samples from 97 mergansers, focusing ducklings (n = 75) 13 different ages but also including birds were 1 yr older. Miracidia hatching...

10.1645/24-110 article EN Journal of Parasitology 2025-03-04

Swimmer's itch (cercarial dermatitis) is a nuisance encountered by bathers and recreational water users worldwide. The condition caused the penetration of larval digenean trematodes (cercariae) family Schistosomatidae, into skin, following their release freshwater from pulmonate snails that serve as intermediate hosts for these parasites. This study utilizes qPCR-based cercariometry to monitor quantify cercariae samples collected at 5 lakes in northern Michigan. resolution provided qPCR...

10.1007/s10393-018-1362-1 article EN cc-by EcoHealth 2018-08-17

Defensive droplets from glandular hairs of the pupa Mexican bean beetle, Epilachna varivestis, contain a group structurally novel alkaloids, azamacrolides. The major constituent this secretion, epilachnene, is shown to be (5Z)-11-propyl-12-azacyclotetradec-5-en-14-olide. secretion also contains an epilachnadiene and trace amounts three closely related components.

10.1073/pnas.90.11.5204 article EN Proceedings of the National Academy of Sciences 1993-06-01

Two novel alkaloids, 2-(12-aminotridecyl)-pyrrolidine and its 1-(2-hydroxyethyl) derivative, are characterized from extracts of adult Mexican bean beetles. These pyrrolidines, together with a previously identified homotropane alkaloid, euphococcinine, account for 90% the alkaloids present in this beetle. A number piperidine derivatives also as minor components. The total mixture represents most complex bouquet reported hitherto any coccinellid

10.1016/0040-4020(93)80019-p article EN cc-by-nc-nd Tetrahedron 1993-01-01

Swimmer’s itch (SI) is a dermatitis in humans caused by cercariae of avian and mammalian schistosomes which emerge from infected snails on daily basis. Mitigation methods for SI have long been sought with little success. Copper sulfate application to the water kill snail hosts historically employed method, but localized, temporary, harmful many aquatic species. Here, we test an alternative method control Trichobilharzia stagnicolae , species well-known cause northern Michigan elsewhere North...

10.1371/journal.pone.0288948 article EN cc-by PLoS ONE 2024-02-15

A novel heptacyclic alkaloid, for which we coin the name chilocorine, was isolated from a ladybird beetle, Chilocorus cacti. It has unique structure made up of two tricyclic substructures, 2-methylperhydro-9b-azaphenalene and 3,4-dimethyloctahydro-8b-azaacenaphthylene. The proposed is based on mass spectrometric, ultraviolet spectroscopic, NMR evidence.

10.1016/s0040-4020(01)86955-6 article EN cc-by-nc-nd Tetrahedron 1994-02-01

The biosynthesis of the azamacrolide epilachnene by coccinellid beetle Epilachna varivestis has been studied with 2H-labeled oleic acid, L-serine, and 13C,15N-labeled L-serine. incorporation these precursors into defines origin alkaloid's entire carbon/nitrogen skeleton. GC/MS GC/IR studies alkaloid produced fed deuteriated acid show that loses four carbon atoms from its carboxyl end during biosynthesis. Other details, including mechanism carbon-nitrogen bond formation between fatty amino...

10.1073/pnas.91.26.12790 article EN Proceedings of the National Academy of Sciences 1994-12-20

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFriedel-Crafts cyclialkylations of some epoxides. 3. Cyclizations tertiary and meta-substituted arylalkyl epoxidesStephen K. Taylor, Curtis L. Blankespoor, Suzanne M. Harvey, Lynell J. RichardsonCite this: Org. Chem. 1988, 53, 14, 3309–3312Publication Date (Print):July 1, 1988Publication History Published online1 May 2002Published inissue 1 July 1988https://pubs.acs.org/doi/10.1021/jo00249a032https://doi.org/10.1021/jo00249a032research-articleACS...

10.1021/jo00249a032 article EN The Journal of Organic Chemistry 1988-07-01

Histologic studies of fish from Douglas Lake, Cheboygan County, Michigan, USA show that Diplostomum spp. infect the lens spottail shiners (Notropis hudsonius) and common (Luxilus cornutus). In contrast, infection was confined to choroidal vasculature yellow perch (Perca flavescens), morphology pigment epithelium retina in regions adjacent metacercariae abnormal. The difference location within host suggested different species may Lake. Species diversity investigated by sequencing barcode...

10.1016/j.ijppaw.2018.05.001 article EN cc-by-nc-nd International Journal for Parasitology Parasites and Wildlife 2018-05-06

Fifty-one common mergansers were captured on Douglas Lake (Cheboygan County, Michigan) and their avian schistosome loads determined by fecal examination. Each bird was given a single dose of 0, 40, or 200 mg/kg body weight praziquantel released. All birds recaptured within 10 days drug administration to determine posttreatment loads. Only the highest found significantly reduce The potential use in swimmer's itch control programs is discussed.

10.1645/0022-3395(2001)087[0424:eopitn]2.0.co;2 article EN Journal of Parasitology 2001-04-01

The defensive glands of beetles, Tenebrio molitor , infected with metacestodes (cysticercoids) Hymenolepis diminuta are everted less frequently upon stimulation, and contain toluquinone (methylbenzoquinone) m -cresol, than uninfected controls. These differences, as shown in predation trials wild rats, increase the likelihood that both cysticercoids beetles will be ingested by tapeworm's definitive host. This is first documented case a parasite inhibiting chemical defence an intermediate...

10.1017/s0031182097008901 article EN Parasitology 1997-07-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCompetitive intramolecular cyclizations of epoxides to aromatic and double bond positionsStephen K. Taylor, David S. Bischoff, Curtis L. Blankespoor, Paul A. Deck, Suzanne M. Harvey, Patricia Johnson, Ariane E. Marolewski, Steven W. Mork, Douglas H. Motry, Ronald Van EenenaamCite this: J. Org. Chem. 1990, 55, 13, 4202–4207Publication Date (Print):June 1, 1990Publication History Published online1 May 2002Published inissue 1 June...

10.1021/jo00300a046 article EN The Journal of Organic Chemistry 1990-06-01

A novel schistosome from Planorbella snails currently known as avian schistosomatid sp. C (ASC) was recently described being capable of causing the papules associated with swimmer's itch. We conducted a paired study 24 human volunteers, exposing each their forearms to five drops water containing cercariae ASC or Trichobilharzia stagnicolae, and examined skin for 1-3 days later. mixed effects model showed that only parasite species significantly affected number papules, while prior...

10.3390/pathogens11060651 article EN cc-by Pathogens 2022-06-04

9-Propyl-10-azacyclododecan-12-olide, a minor component of the defensive secretion Mexican bean beetle (Epilachna varivestis) was synthesized via reductive amination methyl 9-ketododecanoate (3) followed by lactonization. This azamacrolide proved deterrent to ants, but significantly less active than pupal itself.

10.1016/0040-4039(96)00233-x article EN cc-by-nc-nd Tetrahedron Letters 1996-03-01

We had occasion recently to study 3 live specimens of Pseudozaena orientalis opaca , an ozaenine carabid beetle (subfamily Paussinae, tribe Ozaenini) from New Guinea, and report here on the biology chemistry its defensive spray mechanism. A number World ozaenines previously been studied chemically shown be “bombardiers” that discharge a hot quinonoid mixture (Aneshansley et al. 1969, 1983; Eisner Aneshansley 1982; 1977; Roach 1979). proved no exception.

10.1155/1989/31512 article EN cc-by Psyche A Journal of Entomology 1989-01-01

Abstract Swimmer’s itch (SI) is a dermatitis in humans caused by cercariae of avian and mammalian schistosomes which emerge from infected snails on daily basis. Mitigation methods for SI have long been sought with little success. Copper sulfate application to the water kill snail hosts historically employed method, but localized, temporary, harmful many aquatic species. Here, we test an alternative method control Trichobilharzia stagnicolae , species well-known cause northern Michigan...

10.1101/2023.07.10.548414 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2023-07-11

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 100 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”

10.1002/chin.199628258 article EN ChemInform 1996-07-09

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 100 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”

10.1002/chin.199425217 article EN ChemInform 1994-06-21

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 100 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”

10.1002/chin.199404254 article EN ChemInform 1994-01-25

Abstract Treatment of the epoxides (I), (V), and (VIII) with Lewis acids results in formation ring closure products (II), (VI), or (IX) (X), together uncyclized (III) (IV) (VII) (XI) ‐ (XIII).

10.1002/chin.198851167 article EN ChemInform 1988-12-20
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