A5088681787- Fatty Acid Research and Health
- Diet and metabolism studies
- Metabolism and Genetic Disorders
- Adipose Tissue and Metabolism
- Peroxisome Proliferator-Activated Receptors
- Diet, Metabolism, and Disease
- Eicosanoids and Hypertension Pharmacology
- Metabolomics and Mass Spectrometry Studies
- Lipid metabolism and biosynthesis
- Trace Elements in Health
- Mitochondrial Function and Pathology
- Nutritional Studies and Diet
- Cholesterol and Lipid Metabolism
- Advanced MRI Techniques and Applications
- Liver Disease Diagnosis and Treatment
- Muscle metabolism and nutrition
- Phytoestrogen effects and research
- Medical Imaging Techniques and Applications
- Birth, Development, and Health
- Dementia and Cognitive Impairment Research
- Functional Brain Connectivity Studies
- Neuroscience and Neuropharmacology Research
- Alzheimer's disease research and treatments
- Inflammatory mediators and NSAID effects
- Advanced Neuroimaging Techniques and Applications
Université de Sherbrooke
2016-2025
Health and Social Services Centre University Institute of Geriatrics of Sherbrooke
2009-2024
Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean
2016-2022
Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal
2017-2022
Centres Intégré Universitaires de Santé et de Services Sociaux
2017-2021
Centre Hospitalier Universitaire de Sherbrooke
2014-2020
Université de Montréal
1978-2019
Douglas Mental Health University Institute
2019
Centre Hospitalier de l’Université de Montréal
2019
Institut Universitaire en Santé Mentale de Québec
2019
We studied the effect of increasing frequency meals on serum lipid concentrations and carbohydrate tolerance in normal subjects. Seven men were assigned random order to two metabolically identical diets. One diet consisted 17 snacks per day (the nibbling diet), other three three-meal diet); each was followed for weeks. As compared with diet, reduced fasting total cholesterol, low-density lipoprotein apolipoprotein B by a mean (±SE) 8.5±2.5 percent (P<0.02), 13.5±3.4 (P<0.01), 15.1±5.7...
Although high α-linolenic acid flaxseed ( Linum usitatissitmum ) is one of the richest dietary sources α- linolenic and also a good source soluble fibre mucilage, it relatively unstudied in human nutrition. Healthy female volunteers consumed 50 g ground, raw flaxseed/d for 4 weeks which provided 12–13% energy intake (24–25 g/100 total fat). Flaxseed raised long-chain n -3 fatty acids both plasma erythrocyte lipids, as well raising urinary thiocyanate excretion 2.2- fold. lowered serum...
Alzheimer's disease (AD) is generally associated with lower omega-3 fatty acid intake from fish but despite numerous studies, it still unclear whether there are differences in acids plasma or brain. In matched and brain sam
We propose that brain energy deficit is an important pre-symptomatic feature of Alzheimer's disease (AD) requires closer attention in the development AD therapeutics. Our rationale fourfold: (i) Glucose uptake lower frontal cortex people >65 years-old despite cognitive scores are normal for age. (ii) The regional glucose present adults <40 who have genetic or lifestyle risk factors but whom decline has not yet started. Examples include young adult carriers presenilin-1 apolipoprotein E4, and...
Abstract Introduction Unlike for glucose, uptake of the brain's main alternative fuel, ketones, remains normal in mild cognitive impairment (MCI). Ketogenic medium chain triglycerides (kMCTs) could improve cognition MCI by providing brain with more fuel. Methods Fifty‐two subjects were blindly randomized to 30 g/day kMCT or matching placebo. Brain ketone and glucose metabolism (quantified positron emission tomography; primary outcome) performance (secondary assessed at baseline 6 months...
Flaxseed is a rich source of alpha linolenic acid (ALA), fiber and lignans, making it potentially attractive functional food for modulating cardiovascular risk. We studied the effects flaxseed on markers risk in hypercholesterolemic adults.Sixty-two men post-menopausal women with pre-study low density lipoprotein cholesterol (LDL-C) between 130 200 mg/dl were randomized to 40g/day ground flaxseed-containing baked products or matching wheat bran 10 weeks while following fat, diet. Fasting...