- Aquaculture Nutrition and Growth
- Fish Biology and Ecology Studies
- Fish Ecology and Management Studies
- Reproductive biology and impacts on aquatic species
- Aquaculture disease management and microbiota
- Plant Reproductive Biology
- Plant Molecular Biology Research
- Genetic and phenotypic traits in livestock
- Genomics and Phylogenetic Studies
- Genetic diversity and population structure
- MicroRNA in disease regulation
- Animal Genetics and Reproduction
- Antimicrobial Peptides and Activities
- Intracerebral and Subarachnoid Hemorrhage Research
- Cancer-related molecular mechanisms research
- Physiological and biochemical adaptations
- Sperm and Testicular Function
- Invertebrate Immune Response Mechanisms
- Identification and Quantification in Food
- Plant Virus Research Studies
- Protein Hydrolysis and Bioactive Peptides
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Health, Environment, Cognitive Aging
- Kruppel-like factors research
- Acute Ischemic Stroke Management
Henan Polytechnic University
2024
Chinese Academy of Fishery Sciences
2013-2024
Ministry of Agriculture and Rural Affairs
2021-2024
Suzhou Traditional Chinese Medicine Hospital
2024
Jilin University
2024
Hunan University
2020-2024
State Key Laboratory of Chemobiosensing and Chemometrics
2020-2024
Zhengzhou University
2021-2024
Second Hospital of Hebei Medical University
2022-2023
Xingtai People's Hospital
2020-2023
The environmentally responsive signaling pathways that link global transcriptomic changes through alternative splicing (AS) to plant fitness remain unclear. Here, we found the interaction of extracellular rapid alkalinization FACTOR 1 (RALF1) peptide with its receptor FERONIA (FER) triggered a and massive RNA AS response by interacting phosphorylating glycine-rich binding protein7 (GRP7) elevate GRP7 nuclear accumulation in Arabidopsis thaliana. FER-dependent phosphorylation enhanced mRNA...
Rainbow trout (Oncorhynchus mykiss) is one of the world's most widely farmed cold-water fish. However, rise in water temperature caused by global warming has seriously restricted development rainbow aquaculture. In this study, we investigated physiological responses liver exposed to 20 ℃ and 24 returning initial (14 ℃) combining biochemical analyses UPLC-QTOF-MS metabolomics. The results analysis showed that serum aminotransferase, lysozyme, total bilirubin, alkaline phosphatase superoxide...
Abstract Background The receptor-like kinase FEROINA (FER) plays a crucial role in controlling plant vegetative growth partially by sensing the rapid alkalinization factor (RALF) peptide. However, of RALF1-FER vegetative-reproductive transition remains unknown. Here, we analyze mechanism through which FER affects flowering time Arabidopsis. Results We found that mRNA levels exhibit an oscillating pattern with diurnal rhythm and clock oscillator CIRCADIAN CLOCK-ASSOCIATED1 ( CCA1 )...
Mitochondrial DNA (mtDNA) haplogroups have been associated with the incidence of type 2 diabetes (T2D); however, their underlying role in T2D remains poorly elucidated. Here, we report that mtDNA haplogroup N9a was an increased risk occurrence Southern China (odds ratio 1.999 [95% CI 1.229-3.251], P = 0.005). By using transmitochondrial technology, demonstrated activity respiratory chain complexes lower case (N9a1 and N9a10a) than three non-N9a (D4j, G3a2, Y1) this could lead to alterations...
Microcystin-LR (MC-LR) is an intracellular toxin with multi-organ toxicity and the testis one of its important target organs. Although there increasing research on MC-LR in male reproductive toxicity, association between DNA damage autophagy induced by germ cells are still unclear. Therefore, it to explore mechanism MC-LR-induced role activated ATM/p53 signaling pathway testicular toxicity. The present study showed that exposure significantly reduced gonadal index pathological testes mice....
Thrombocytopenia during pregnancy is a common hematological abnormality with complex and diverse etiologies, involving physiological changes pregnancy, immune factors, genetic other underlying diseases. Based on etiology, thrombocytopenia can be classified into pregnancy-specific non-pregnancy-specific categories. The impact of caused by different etiologies outcomes varies. This article reviews the related research progress outcomes, aiming to provide theoretical basis for early clinical...
ABSTRACT Objective Cerebral hemorrhage is a severe condition associated with high morbidity and mortality. Understanding the underlying pathogenesis crucial for developing effective therapeutic strategies. This study aimed to investigate role of dysregulated α2δ‐1 protein in cerebral hemorrhage. Materials Methods We observed significant upregulation tissue. Knockdown resulted decreased intracellular calcium concentration reduced phosphorylation PLCr IP3R presence calcium. Additionally,...
Chromosomal ploidy manipulation is one of the means to create excellent germplasm. Triploid fish could provide an ideal sterile model for searching a underlying mechanism abnormality in meiosis. The complete understanding coding and noncoding RNAs regulating sterility caused by meiosis still not well understood. By high-throughput sequencing, we compared expression profiles gonadal mRNA, long non-coding RNA (lncRNA), microRNA (miRNA) at three different developmental stages between diploid...
This study was conducted to estimate the effects of dietary protein and lipid levels on growth, body composition, gonadal development activity liver metabolic enzymes brown trout Salmo trutta fario broodstock. Ten diets were formulated containing five different (360, 390, 420, 450 480 g/kg) two (90 180 g/kg). The experiment a completely randomized 5 × 2 factorial design. fish with an initial weight 462.53 ± 45.40 g cultured in spring water flow-through system for 77 days. growth performance...
Chronic hepatitis B virus (HBV) infection has been reported to be associated with the prevalence of non‑alcoholic fatty liver disease (NAFLD). However, present study demonstrated that incidence in HBV‑infected subjects (16/152, 10.5%) was not significantly different from non‑HBV‑infected (292/1,714, 17%), following adjustment for age (odds ratio=0.656; 95% confidence interval=0.379‑1.134; P=0.131). Hepatitis protein X (HBx) is considered a key regulator HBV and several studies have confirmed...
Abstract This work aims to investigate the potential of fiber‐optic Fourier transform‐near‐infrared (FT‐NIR) spectrometry associated with chemometric analysis, which will be applied monitor time‐related changes in residual sugar and alcohol strength during kiwi wine fermentation. NIR calibration models for fermentation were established on FT‐NIR spectra 98 samples scanned a spectrometer, partial least squares regression method. The results showed that R 2 root mean square error...
Abstract A generally used chemotherapeutic drug for glioma, a frequently diagnosed brain tumour, is temozolomide (TMZ). Our study investigated the activity of FBXL7 and miR‐152‐5p in glioma. Levels microRNA‐152‐5p (miR‐152‐5p) transcript protein were assessed by real‐time PCR Western blotting, respectively. The migratory invasive properties cells measured Transwell migration invasion assay their viability examined using CCK‐8 assay. Further, putative interaction between analysed...
Human mitochondrial DNA (mtDNA) variants and haplogroups may contribute to susceptibility various diseases pathological conditions, but the underlying mechanisms are not well understood. To address this issue, we established a cytoplasmic hybrid (cybrid) system investigate role of mtDNA in human disease; specifically, examined effects East Asian genetic backgrounds on oxidative phosphorylation (OxPhos). We found that single nucleotide polymorphisms such as m.489T>C, m.10398A>G,...
Various long-lived mRNAs are stored in seeds, some of which required for the initial phase germination and critical to seed longevity. However, seed-specific involved longevity remain poorly understood rice. To identify these we first performed aging experiment with 14 rice varieties, categorized them as higher (HL) lower (LL) varieties conventional hybrid rice, respectively. Second, RNA-seq analysis showed that most genes similar tendency expression changes during natural artificial aging,...
Rainbow trout (Oncorhynchus mykiss) is a typical cold-water aquaculture fish and high-end aquatic product. When water temperature exceeds its optimal range of 12–18 °C, the immune system rainbow becomes weakened unbalanced. High in summer global warming severely impact industry. The focus this study was to explore mechanisms regulating response under high stress identify molecular elements that account for resistance temperature. In study, individual were screened experiment divided into...