- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Ophthalmology and Visual Impairment Studies
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Retinal Imaging and Analysis
- Ophthalmology and Visual Health Research
- Retinal and Optic Conditions
- Ocular Surface and Contact Lens
- Retinal and Macular Surgery
- Health disparities and outcomes
- Ocular Diseases and Behçet’s Syndrome
- Electronic Health Records Systems
- Global Maternal and Child Health
- Corneal Surgery and Treatments
- Patient Satisfaction in Healthcare
- Biomedical Text Mining and Ontologies
- Health Systems, Economic Evaluations, Quality of Life
- Aging and Gerontology Research
- Traumatic Ocular and Foreign Body Injuries
- Balance, Gait, and Falls Prevention
- Medical Malpractice and Liability Issues
- Connexins and lens biology
- Healthcare Systems and Reforms
- Telemedicine and Telehealth Implementation
University of Utah
2014-2025
Outcomes Research Consortium
2024
Eye Institute of Utah
2009-2022
University of Michigan
2017-2021
Duke Medical Center
2021
University of Utah Health Care
2021
Institute of Population and Public Health
2021
Duke University
2019-2020
University of California, San Diego
2019
National Eye Institute
2019
Vision impairment (VI) and mental health conditions are highly prevalent among older adults major causes of morbidity care expenditures. However, there few nationally representative data from the United States on longitudinal association between VI depressive symptoms, no such anxiety symptoms.To evaluate directionality self-reported clinically significant symptoms depression in US adults.The National Health Aging Trends Study, a survey administered annually 2011 to 2016 cohort Medicare...
Abstract Background Physicians in training are at high risk for depression, and physicians practice have a substantially elevated of suicide compared to the general population. The graduate medical education community is currently mobilizing efforts improve resident wellness. Objective We sought provide trainee perspective on current resources support wellness that need be developed ensure an optimal learning environment. Methods ACGME Council Review Committee Residents, 29-member...
Objectives To determine the prevalence of falls, fear falling (FoF), and activity limitation due to FoF in a nationally representative study older adults with self‐reported vision impairment (VI). Design Cross‐sectional analysis panel survey data. Setting National Health Aging Trends Study, administered annually from 2011 2016 U.S. Medicare beneficiaries aged 65 older. Participants Respondents (N=11,558) who contributed 36,229 participant observations. Measurements We performed logistic...
Monthly intraocular injections are widely used to deliver protein-based drugs that cannot cross the blood-retina barrier for treatment of leading blinding diseases such as age-related macular degeneration (AMD). This invasive carries significant risks, including bleeding, pain, infection, and retinal detachment. Further, current therapies associated with a rate fibrosis geographic atrophy significantly higher than which occurs in described natural history AMD. A novel therapeutic strategy...
Background:Glaucoma is the leading cause of irreversible blindness worldwide. Access to glaucoma specialists challenging and likely become more difficult as population ages. Introduction:Using telemedicine for (teleglaucoma) has potential increase access care by improving efficiency decreasing need long-distance travel patients. Results:Teleglaucoma programs can be used screening, diagnostic consultation, long-term treatment monitoring. Key components teleglaucoma include patient history,...
Vision impairment (VI) is associated with falls in older adults. However, past studies have relied on geographically constrained samples limited generalizability or self-reports of visual difficulty. To date, there not been nationally representative the association objective measures function and outcomes.
Purpose.: To determine the efficacy of a plasmid containing small hairpin RNA expression cassette (pSEC.shRNA) against VEGF-A–loaded poly(lactic co-glycolic acid) nanoparticles (PLGA NPs) in sustained regression murine corneal neovascularization. Methods.: PLGA were loaded with pSEC.shRNA.VEGF-A plasmids using double emulsion-solvent evaporation method. KNV was induced BALB/c mice by mechanical-alkali injury. Four weeks after induction KNV, randomly divided to receive one four treatments...
<h3>Importance</h3> Vision impairment (VI), including blindness, affects hundreds of millions globally, and 90% those with VI live in low- middle-income countries. Cross-national comparisons are important to elucidate the unique shared factors associated receipt eye care different countries target most need. <h3>Objective</h3> To identify characteristics a sample <h3>Design, Setting, Participants</h3> In this study cross-sectional survey data from wave 1 World Health Organization Study on...
<h3>Importance</h3> The number of older adults with visual impairment (VI) and dementia is projected to increase in the US because aging population. Dementia VI commonly co-occur are each independently associated disability. To care for an population, it may be important characterize association coexisting self-reported on daily functioning. <h3>Objective</h3> evaluate co-occurring <h3>Design, Setting, Participants</h3> This cross-sectional analysis a nationally representative cohort study...
<h3>Importance</h3> Cataract surgery is commonly performed at ambulatory centers (ASCs) and hospital outpatient departments (HOPDs). These venues differ in many ways, including surgical efficiency, patient throughput, safety, costs per surgery. <h3>Objective</h3> To determine trends use of ASCs HOPDs for cataract from 2001 to 2014 factors affecting the site <h3>Design, Setting, Participants</h3> This retrospective longitudinal cohort analysis involved individuals 40 years older who underwent...
Abstract Background Vision impairment (VI) in older adults is associated with declines well-being. However, the pathways through which poor vision leads to well-being have not been well-described. The purpose of this study was determine whether activity limitations and social participation restrictions mediate impact self-reported VI on subjective Methods National Health Aging Trends Study (NHATS) a nationally representative longitudinal Medicare beneficiaries 65 that includes detailed...
Clinical decision-making is based on knowledge, expertise, and authority, with clinicians approving almost every intervention-the starting point for delivery of "All the right care, but only care," an unachieved healthcare quality improvement goal. Unaided suffer from human cognitive limitations biases when decisions are their training, experience. Electronic health records (EHRs) could improve robust decision-support tools that reduce unwarranted variation clinician actions. Current EHRs,...
Standardization of eye care data is important for clinical interoperability and research. We aimed to address gaps in the representations glaucoma examination concepts within Systemized Nomenclature Medicine - Clinical Terms (SNOMED-CT), preferred terminology American Academy Ophthalmology.
Background/Aims To investigate racial differences in the variability of longitudinal visual field testing a ‘real-world’ clinical population, evaluate how these are influenced by socioeconomic status, and estimate impact on time to detect progression. Methods This retrospective observational cohort study used data from 1103 eyes 751 White individuals 428 317 black individuals. Linear regression was performed standard automated perimetry mean deviation values for each eye over time. The SD...
Precis: In this multi-institutional effort, we identified gaps in SAP data elements within medical terminologies. We proposed new concepts to LOINC enhance standards and big representation improve interoperability across healthcare systems. Purpose: To identify the of Standard Automated Perimetry (SAP) Logical Observation Identifiers Names Codes (LOINC) Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM) propose solutions for those gaps. Methods: source Digital Imaging...
In this study, we compare the 12-month results of eyes that underwent ab externo, open-conjunctival XEN45 gel stent placement with mitomycin C (MMC) and without intraoperative addition Ologen collagen matrix (XEN45 + groups, respectively). Intraocular pressure (IOP) measurements were recorded postoperation at 1 month, 3 months, 6 9 IOP reduction, reduction in number IOP-lowering medications, success rate compared between groups. A complete was defined as a ≥20% drop from baseline 12 months...
PurposeDiabetic macular edema (DME), a leading cause of visual impairment, can occur regardless diabetic retinopathy (DR) stage. Poor metabolic control is hypothesized to contribute DME development though large-scale studies have yet identify such an association. This study aims determine whether measurable markers dysmetabolism associate with in persons diabetes.DesignRetrospective cohort studyParticipantsUsing data from the Sight Outcomes Research Collaborative (SOURCE) repository,...
To evaluate the optimum on time for most efficient removal of lens fragments using micropulsed ultrasound (US).John A. Moran Eye Center Laboratories, University Utah, Salt Lake City, USA.Experimental study.Twenty porcine nuclei were soaked in formalin 2 hours and then divided into 2.0 mm cubes. Using an US machine with a 0.9 bent 30-degree bevel tip, was varied every millisecond (ms) from ms to 10 off kept constant at ms. Efficiency (time removal) chatter (number fragment repulsions tip)...