A5108653752- Advanced biosensing and bioanalysis techniques
- Protein Interaction Studies and Fluorescence Analysis
- Carbon and Quantum Dots Applications
- Advanced Chemical Sensor Technologies
- DNA and Nucleic Acid Chemistry
- Electrochemical sensors and biosensors
- Metal complexes synthesis and properties
- Molecular Sensors and Ion Detection
- Biosensors and Analytical Detection
- Lanthanide and Transition Metal Complexes
- Advanced Nanomaterials in Catalysis
- Nanocluster Synthesis and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Analytical Chemistry and Sensors
- Advanced Biosensing Techniques and Applications
- RNA Interference and Gene Delivery
- Chemical Synthesis and Characterization
- Electron Spin Resonance Studies
- Monoclonal and Polyclonal Antibodies Research
- Analytical Chemistry and Chromatography
- Olfactory and Sensory Function Studies
- Protein purification and stability
- Protein Structure and Dynamics
- Innovative Microfluidic and Catalytic Techniques Innovation
- Pharmacological Effects and Toxicity Studies
Ningbo Institute of Industrial Technology
2015-2025
Chinese Academy of Sciences
2015-2025
North China University of Science and Technology
2025
University of Chinese Academy of Sciences
2018
Molina Center for Energy and the Environment
2018
Shantou University
2010-2012
Due to relatively low persistence and high effectiveness for insect pest eradication, organophosphates (OPs) carbamates are the two major classes of pesticides that broadly used in agriculture. Hence, sensitive selective detection OPs is highly significant. In this current study, a colorimetric sensor array comprising five inexpensive commercially available thiocholine H2O2 indicators simultaneous identification developed. The sensing mechanism based on irreversible inhibition capability...
Developing highly active and sensitive nanozymes for biothiol analysis is of vital significance due to their essential roles in disease diagnosis. Herein, two metal ion-doped carbon dots (M-CDs) with high peroxidase-like activity were designed prepared detection identification through the colorimetric sensor array technique. The M-CDs can strongly catalyze decomposition H2O2, accompanied by color changes 3,3′,5,5′-tetramethylbenzidine (TMB) from colorless blue, indicating...
Fluorescent carbon dots (CDs) are attracting much attention in sensing recently thanks to their superior optical properties and abundant surface functional groups. To take further advantages of these unique features, CDs considered be possible for facilely fabricating multichannel sensor arrays. As a proof-of-concept research, CDs-metal ions ensembles screened designed as triple-channel fluorescent array this study the identification various phosphate anions (e.g., ATP, ADP, AMP, PPi, Pi)...
Fluorescence lateral flow immunoassays (FL-LFIA) have attracted considerable attention in clinical diagnosis due to their outstanding merits of affordable, sensitive, on-site, and quick detection. However, they are still plagued by significant signal interference, such as autofluorescence scattered light. The development high-performance robust phosphors, i.e., label probes featuring with the character low/no optical background, remains a great challenge. Herein, we report novel visualized...
In this work, a bioprobe for the detection of dopamine was designed and fabricated through covalently linking fluorescent carbon dots (CDs) tyrosinase (TYR). The (named CDs-TYR) can catalyze oxidation produce dopaquinone, consequently fluorescence CDs quenched due to an efficient electron transfer mechanism from excited dopaquinone. intensity decreased in dopamine-concentration-dependent manner, which built foundation quantification. provided wide linear range 0.1 6.0 μM sensing....
In this contribution, bovine serum albumin stabilized gold nanoclusters as novel fluorescent probes were successfully utilized for the detection of methotrexate first time. Our prepared exhibited strong emission with peak maximum at 633.5 nm. However, addition induced fluorescence intensity to decrease. The decrease in caused by allowed sensitive range 0.0016 μg mL−1 24 mL−1. limit is 0.9 ng a signal-to-noise ratio 3. present sensor possessed low and wide linear range. addition, real samples...
Abstract Fluorescent carbon dots (CDs) have received considerable attention in recent years due to their superior optical properties. To take further advantages of these unique features, herein, a CDs‐based “lab‐on‐a‐nanoparticle” approach for the detection and discrimination antibiotics is developed. The sensing platform was designed based on different channel's fluorescence recoveries or quenching full‐color emissive CDs (F‐CDs) metal ion ensembles upon addition antibiotics. F‐CDs...
By virtue of the fascinating merits low cost, rapid screening, and on-site detection, fluorescence lateral flow assays (FLFAs) have attracted considerable attention. Their detection limits are closely associated with label probes used. The development high-performance robust phosphors remains a great challenge. Herein, we presented new probe, i.e., fluorescent carbon nanobeads (FCNBs), for FLFAs. Monodispersive, water-soluble, highly emissive FCNBs were facilely prepared via hydrothermal...
pH-Sensitive oligopeptide magnetic mesoporous silica beads were successfully prepared by using large-pore dendritic colloids as templates for DNA extraction.
The scheme of zirconia bead-mediated ultrasonic fragmentation long-stranded DNA.
Animal-derived foods constitute a crucial source of nutrients for humans. The judicious application steroid hormones in the breeding process can serve multiple purposes, including growth promotion, weight gain, and anti-inflammatory effects, among others. However, excessive misuse poses considerable risk to both food safety consumer health. Currently, primary means detecting involve liquid chromatography, gas their combination with mass spectrometry. These methods necessitate advanced...
Abstract Multidimensional sensing offers advantages in accuracy, diversity and capability for the simultaneous detection discrimination of multiple analytes, however, previous reports usually require complicated synthesis/fabrication process and/or need a variety techniques (or instruments) to acquire signals. Therefore, take full this concept, simple designs are highly desirable. Herein, novel concept is conceived construct multidimensional platforms based on single indicator that has...
Although some colorimetric sensor arrays have been developed for the identification of Chinese liquors, they usually require confirmation volatile markers in liquors by chromatography and mass spectrometry firstly. Herein, we present a simple array to identify various liquid phase without aid other analytical techniques. The consists six commercially available inexpensive solvatochromic dyes, sensing mechanism this is based on response dyes their local polarity. On basis colour changes...
A very facile approach for the design and fabrication of a colorimetric sensor array, by using only single indicator–receptor couple at various ratios concentrations, is described first time.
A novel assay has been developed to detect the interaction of DNA and anticancer drugs based on decreased resonance light scattering (RLS) technique. The proposed method can be used study those which do not produce a RLS-signal after binding DNA. RLS was monitor five with reaction between took place in BR buffer solution. From assay, sequence activities as follows: CTX < MTX Pt MMC 5-Fu. Mammary cancer cell (mcDNA) involved validate assay. results showed that sensitivities targeting both...