Purnima Dey Sarkar

ORCID: 0000-0003-4024-8820
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About
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Research Areas
  • Pregnancy and preeclampsia studies
  • Adipokines, Inflammation, and Metabolic Diseases
  • Antioxidant Activity and Oxidative Stress
  • Birth, Development, and Health
  • Biochemical effects in animals
  • Bone health and osteoporosis research
  • Chronic Kidney Disease and Diabetes
  • Vitamin C and Antioxidants Research
  • Electrolyte and hormonal disorders
  • Paraoxonase enzyme and polymorphisms
  • Liver Disease Diagnosis and Treatment
  • Hemoglobinopathies and Related Disorders
  • Parathyroid Disorders and Treatments
  • Oral microbiology and periodontitis research
  • Biochemical Acid Research Studies
  • Renal Diseases and Glomerulopathies
  • Apelin-related biomedical research
  • Bone Metabolism and Diseases
  • Phytoestrogen effects and research
  • Advanced Glycation End Products research
  • Gestational Diabetes Research and Management
  • Biomarkers in Disease Mechanisms
  • Neonatal Respiratory Health Research
  • Treatment of Major Depression
  • Infant Nutrition and Health

Mahatma Gandhi Memorial Medical College
2013-2023

Maharaja Yeshwantrao Hospital
2016

Gandhi Medical College
2011

Post Graduate Institute of Medical Education and Research
1991-1992

Netaji Subhash Chandra Bose Medical College
1970

Objective: To assess the relationship of serum osteocalcin levels with blood glucose, insulin resistance and lipid profile in central Indian men type 2 diabetes.Methods: Anthropometric biochemical parameters were measured 56 newly diagnosed diabetic age body mass index (BMI) matched controls. Insulin was calculated by homeostasis model assessment (HOMA-IR).Results: After adjustment for BMI, negatively correlated fasting plasma glucose (p = 0.0004), 0.0311), HOMA-IR 0.0023), triglycerides...

10.3109/13813455.2012.715651 article EN Archives of Physiology and Biochemistry 2012-09-14

Background: Preeclampsia affects about 5-8% of all pregnancies and is a major cause maternal, fetal neonatal mortality morbidity. Evidences prove that endothelial cell altered function play an important role in the pathogenesis preeclampsia. Therefore serum lactate dehydrogenase (LDH) gamma glutamyl transferase (GGT) are useful biochemical markers reflecting severity occurrence The objective was todetermine as preeclamptic pregnant women its comparison with normal third trimester.Methods:...

10.5455/2320-6012.ijrms20131110 article EN International Journal of Research in Medical Sciences 2013-01-01

Objective: To analyse the association of osteocalcin with insulin resistance and type 2 diabetes assess role adiponectin in these relationships. Methods: This study comprised 98 newly diagnosed diabetic women (51 pre-menopausal 47 post-menopausal) 102 age BMI matched controls (53 49 post-menopausal). Insulin was calculated by homeostasis model assessment-insulin (HOMA-IR). Results: Osteocalcin significantly positively correlated both (p = 0.0026) post-menopausal 0.0357). Significant negative...

10.3109/13813455.2013.877488 article EN Archives of Physiology and Biochemistry 2014-01-09

Background Initial evidences have shown that diabetes mellitus occurs concomitantly with obsessive-compulsive disorder (OCD) symptomatology. Serotonergic psychiatric therapy posits serotonin is a central character in the management of OCD. Hence, it worth investigating novel chemical entities affecting serotonergic system for targeting An isoflavonoid phytoestrogen, genistein, has been recognized as great pharmacological value especially protecting neurodegeneration, depression (serotonin...

10.1515/jbcpp-2017-0155 article EN Journal of Basic and Clinical Physiology and Pharmacology 2018-03-21

The purpose of this investigation was to assess the influence music on emergence phenomena after ketamine anaesthesia. Fifty ASA 1 patients undergoing minor gynaecological procedures were randomly divided into two equal groups. Patients in treated group played their choice through headphones from 5 min before induction anaesthesia 15 postoperatively. Although incidence similar both groups effects tended be more pleasant and acceptable those whom played. majority study (80%) expressed...

10.1111/j.1365-2044.1992.tb02230.x article EN Anaesthesia 1992-05-01

Preterm is defined as a baby with gestation of less than 37 completed weeks. In this study, serum calcium, phosphorus, ALP, creatinine, and electrolytes were measured in preterm babies. The present study comprised 75 babies which 25 28–30 weeks, 30–32 remaining 34–36 weeks (controls) gestational age. Serum calcium phosphorus levels found to be significantly decreased, increased () at compared controls, but phosphorous insignificantly whereas ALP activities age It can concluded that high...

10.1155/2011/740370 article EN cc-by Biochemistry Research International 2011-01-01

Sulindac is an analgesic and anti-inflammatory agent. It has the general side-effects of non-steroidal drugs, owing to presence a free carboxylic acid group. The aim study was retard adverse gastrointestinal effects drug. Various conjugates sulindac were synthesized by amidation with methyl esters 10 amino acids. characterized melting-point, thin-layer chromatography Fourier transform infrared, nuclear magnetic resonance mass spectroscopy. evaluated pharmacologically for analgesic,...

10.1016/j.jtusci.2014.11.005 article EN cc-by-nc-nd Journal of Taibah University for Science 2014-12-23

Preeclampsia is referred to as the “disease of theories” because multiple hypotheses proposed explain its occurrence. Despite considerable research, causes preeclampsia remain unclear. It multifactorial in nature and recent research has focused on measurements various prothrombotic markers for detection latent clotting pathway activation. This study was undertaken determine changes levels plasma Antithrombin -III (AT-III) platelet count preeclamptic women comparison with healthy non-pregnant...

10.5455/2320-1770.ijrcog20130927 article EN International Journal of Reproduction Contraception Obstetrics and Gynecology 2013-01-01

Cardiovascular disease is the most frequent cause of death in patient with diabetes. It difficult to evaluate cardiovascular status patients diabetes because complex symptomatology. NTproBNP, a split peptide from pro BNP molecule novel biomarker, released cardiac myocytes response myocardial stretch, cardio vascular disease, endothelial dysfunction and heart failure. We aimed test that elevated NTproBNP levels associated increased risk comparison matched control. Demographic, anthropometric...

10.3329/jom.v11i1.4266 article EN cc-by Journal of Medicine 1970-01-01

Diabetic nephropathy (DN) is the most common microvascular complication observed in patients with type-2 diabetes mellitus. Furthermore, magnesium (Mg) deficiency a problem diabetic patients. In this study, we estimated levels of Mg, which an important trace element and pro-oxidant marker, then evaluated association between serum Mg pro-oxidants DN. present 200 were enrolled divided into two groups. The control DN groups consisted 100 healthy individuals DN, respectively. Serum total...

10.4103/1319-2442.270257 article EN cc-by-nc-sa Saudi Journal of Kidney Diseases and Transplantation 2019-01-01

Nurses play a strong role in helping patients reduce their risk for disease and make informed lifestyle changes. Reliability of the nurses is critical them to serve as models educators. The aim present study was improve nurse knowledge post-myocardial infarction rehabilitation at selected hospitals Indore through newly designed self-instructional module. Sixty cardiac center staff were administered questionnaire, pre-test on care Five days after module, post-test given assess gain...

10.1016/j.ijnss.2015.07.004 article EN cc-by-nc-nd International Journal of Nursing Sciences 2015-08-07
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