- Transgenic Plants and Applications
- Enzyme Catalysis and Immobilization
- Homelessness and Social Issues
- Intraperitoneal and Appendiceal Malignancies
- Evolutionary Psychology and Human Behavior
- Human-Animal Interaction Studies
- Clostridium difficile and Clostridium perfringens research
- Pancreatitis Pathology and Treatment
- Plant tissue culture and regeneration
- Algal biology and biofuel production
- Advanced Drug Delivery Systems
- Neuroendocrine regulation and behavior
- Viral Infectious Diseases and Gene Expression in Insects
- Monoclonal and Polyclonal Antibodies Research
- Ovarian cancer diagnosis and treatment
University of Wisconsin–Madison
2021
Temple University Hospital
2019
The use of the edible photosynthetic cyanobacterium Arthrospira platensis (spirulina) as a biomanufacturing platform has been limited by lack genetic tools. Here we report engineering methods for stable, high-level expression bioactive proteins in spirulina, including large-scale, indoor cultivation and downstream processing methods. Following targeted integration exogenous genes into spirulina chromosome (chr), encoded protein biopharmaceuticals can represent much 15% total biomass, require...
ABSTRACT Arthrospira platensis (commonly known as spirulina) is a photosynthetic cyanobacterium 1 . It highly nutritious food that has been consumed for decades in the US, and even longer by indigenous cultures 2 Its widespread use safe source proven scalability have driven frequent attempts to convert it into biomanufacturing platform. But these were repeatedly frustrated spirulina’s genetic intractability. We report here efficient versatile engineering methodology spirulina allows stable...
Abstract Drugs which independently inhibit a shared target or pathway can have synthetic activities that result in multiplicative instead of merely additive potencies. This characteristic drug combinations be quantified by expressing the potency combination as if it were single agent. We show optimizing this quantity we prospectively design cocktails with apparent potencies far exceed any its individual components. illustrate power approach, is based on statistical experiments to select...
Abstract Transmission of maternal behavior across generations occurs, but less is known about paternal behavior. In biparental species like the California mouse ( Peromyscus californicus ), care contributes to well‐being offspring with lasting consequences on brain and Paternal huddling/grooming can be passed future generations, whether retrieval, which removes young from potential harm, transmitted independently unclear. We manipulated retrieval experience through pup displacement...
Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Facebook Twitter LinkedIn MailTo Tools Get Permissions Cite Search Site Citation Lauren Goetsch; Invisible Nation: Homeless Families in America. Journal of Baccalaureate Social Work 1 January 2017; 22 (1): 127–130. doi: https://doi.org/10.18084/1084-7219.22.1.127 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Dropdown...