Brigitte Leeners

ORCID: 0000-0003-4027-6151
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Endometriosis Research and Treatment
  • Pregnancy and preeclampsia studies
  • Sexual function and dysfunction studies
  • Pregnancy-related medical research
  • Child Abuse and Trauma
  • Birth, Development, and Health
  • Reproductive Biology and Fertility
  • Uterine Myomas and Treatments
  • Ovarian function and disorders
  • Pregnancy and Medication Impact
  • Adolescent Sexual and Reproductive Health
  • Reproductive Health and Technologies
  • Menstrual Health and Disorders
  • Sexuality, Behavior, and Technology
  • Menopause: Health Impacts and Treatments
  • Health and Medical Studies
  • Medical and Health Sciences Research
  • Sex work and related issues
  • Social and Demographic Issues in Germany
  • Gynecological conditions and treatments
  • Reproductive Health and Contraception
  • Maternal and Perinatal Health Interventions
  • Estrogen and related hormone effects
  • Maternal Mental Health During Pregnancy and Postpartum
  • Gestational Diabetes Research and Management

Center for Pediatric Endocrinology Zurich
2013-2025

University Hospital of Zurich
2016-2025

University of Zurich
2006-2024

Swiss Integrative Center for Human Health
2016-2024

Universitäts Frauenklinik
2000-2023

RELX Group (United States)
2019

Olgahospital
1998-2017

Universitätsklinikum Aachen
1996-2014

RWTH Aachen University
1998-2011

Klinik für Frauenheilkunde
2004-2009

Is fatigue a frequent symptom of endometriosis? Fatigue is an underestimated endometriosis as it affects the majority women with endometriosis, but not widely discussed in literature. can be causing major distress impacting daily activities and quality life endometriosis. However, few studies large sample sizes have investigated The study was designed multi-center matched case–control study. Recruitment took place at hospitals private practices Switzerland, Germany Austria between 2010 2016....

10.1093/humrep/dey115 article EN Human Reproduction 2018-05-14

Core and peripheral body temperatures are affected by changes in reproductive hormones during the menstrual cycle. Women worldwide use basal temperature (BBT) method to aid prevent conception. However, prior research suggests that taking one's daily can prove inconvenient subject environmental factors. We investigate whether a more automatic, non-invasive measurement system detect across examined how wrist skin (WST), measured with wearable sensors, correlates urinary tests of ovulation may...

10.1042/bsr20171279 article EN Bioscience Reports 2017-11-25

Previous research examining physiological changes across the menstrual cycle has considered biological responses to shifting hormones in isolation. Clinical studies, for example, have shown that women's nightly basal body temperature increases from 0.28 0.56 ˚C following postovulation progesterone production. Women's resting pulse rate, respiratory and heart rate variability (HRV) are similarly elevated luteal phase, whereas skin perfusion decreases significantly fertile window's closing....

10.2196/13404 article EN cc-by Journal of Medical Internet Research 2019-03-24

To explore the association between childhood sexual abuse (CSA), physical abuse, as well other adverse experiences (ACE), and different obstetrical risk factors/behaviors.In this cohort study, factors perinatal outcome in 85 women exposed to CSA were compared 170 matched unexposed women. CSA, ACE explored by face-to-face interviews questionnaire. Data on extracted from medical charts. Fisher's exact, χ2-test, multiple logistic regression used for statistical analysis.During pregnancy with...

10.1515/jpm-2013-0003 article EN Journal of Perinatal Medicine 2013-12-13
James MN Duffy Hisham Alahwany Siladitya Bhattacharya Barbara Collura Cate Curtis and 93 more J.L.H. Evers Roy G. Farquharson Sebastian Franik Linda C. Giudice Yacoub Khalaf J.M.L. Knijnenburg Brigitte Leeners Richard S. Legro Sarah Lensen Juan Carlos Vázquez-Niebla D. Mavrelos Ben W. Mol Craig Niederberger Ernest Hung Yu Ng A.S. Otter Lucian Puşcaşiu Satu Rautakallio-Hokkanen Sjoerd Repping Ippokratis Sarris Joe Leigh Simpson Annika Strandell C. Strawbridge Helen L. Torrance Andy Vail Madelon van Wely M. Vercoe Lan N. Vuong Alex Wang Rui Wang Jack Wilkinson Mohamed Youssef Cindy Farquhar Ahmed M Abou-Setta Juan J. Aguilera Oluseyi O.A. Atanda Eva Balkenende Kurt T. Barnhart Yusuf Beebeejaun Siladitya Bhattacharya Megan Black Magdalena Bofill Georgina M. Chambers Abrar Ahmad Chughtai Javier Crosby Irene Cuevas Arianna D'Angel Danielle D. Dubois Kirsten Duckitt Carlos García Encinas Anita Fincham Marie-Odile Gerval Nhu H. Giang Ahmed Gibreel Lynda J. Gingel Elizabeth Glanville Demián Glujovsky Ingrid Granne Georg Griesinger Devashana Gupta Zeinab Hamzehgardeshi Martha Hickey Martin Hirsch Marcos Horton M. Louise Hull Shikha Jain Marta J. Perez Claire Jones Vanessa Jordan Mohan S. Kamath Elena Kostova Antonio La Marca Tien Khac Le Arthur Leader Jian Li Olabisi Loto Karen L. Marks Alison McTavish David J. Mills R. Nair Dung Thi Phuong Nguyen Allan Pacey Lynn Sadler Peggy Sagle Juan-Enrique Schwarze Heather Shapiro Marian Showell Charalampos Siristatidis Akanksha Sood C. Tu Emma L. Votteler Chi Chiu Wang Andrew Watson Menem Yossry

Can a core outcome set to standardize selection, collection and reporting across future infertility research be developed?A minimum data set, known as has been developed for randomized controlled trials (RCTs) systematic reviews evaluating potential treatments infertility.Complex issues, including failure consider the perspectives of people with fertility problems when selecting outcomes, variations in definitions selective outcomes on basis statistical analysis, make results difficult...

10.1093/humrep/deaa241 article EN cc-by-nc Human Reproduction 2020-09-01

Background As a daily point measurement, basal body temperature (BBT) might not be able to capture the shift in menstrual cycle because single measurement is present on sliding scale of circadian rhythm. Wrist skin measured continuously during sleep has potential overcome this limitation. Objective This study compares diagnostic accuracy these two temperatures for detecting ovulation and investigate correlation agreement between describing thermal changes cycles. Methods prospective included...

10.2196/20710 article EN cc-by Journal of Medical Internet Research 2021-06-08

Abstract Background Pain plays a central role in endometriosis. The complex relationship among pain characteristics, comorbid disorders and daily life represents challenge for medical support. This multicentre cross‐sectional case–control study analysed the association between endometriosis‐related chronic functions of 510 women with endometriosis, 265 (52%) who experienced pain, either from endometriosis alone ( N = 134, 26.3%) or additional 131, 25.7%). Methods Self‐administered...

10.1002/ejp.1926 article EN cc-by-nc-nd European Journal of Pain 2022-02-20

An affordable, user-friendly fertility-monitoring tool remains an unmet need. We examine in this study the correlation between pulse rate (PR) and menstrual phases using wrist-worn PR sensors. 91 healthy, non-pregnant women, 22-42 years old, were recruited for a prospective-observational clinical trial. Participants measured during sleep bracelets with photoplethysmographic Ovulation day was estimated "Clearblue Digital-Ovulation-urine test". Potential behavioral nutritional confounders...

10.1038/s41598-017-01433-9 article EN cc-by Scientific Reports 2017-04-25

Is maltreatment during childhood (MC), e.g. sexual abuse, physical emotional abuse and neglect, associated with diagnosis of endometriosis?Childhood abuse/neglect inconsistency experiences were the endometriosis while no such association was found for other forms maltreatment.Symptoms as chronic pelvic pain, fatigue depression, are correlated MC, immune reactions linked to endometriosis. These factors support a case potential role MC in development endometriosis.The study designed...

10.1093/humrep/dey111 article EN Human Reproduction 2018-05-03

Endometriosis affects various aspects of women’s lives. We searched for predictors patient satisfaction with medical support (PSwMS) in women endometriosis. The study was designed as a multi-centre retrospective cohort study. approached histologically confirmed endometriosis from 2010 until 2016, comparing satisfied to dissatisfied support. analysed data on characteristics endometriosis, PSwMS and the influence disease PSwMS. Information collected through standardized questionnaire. After...

10.1371/journal.pone.0208023 article EN cc-by PLoS ONE 2018-11-29

Objectives Endometriosis is a gynaecological disease most commonly causing severe and chronic pelvic pain as well an impaired quality of life. The aim this study was to investigate if how endometriosis affects choices regarding professional life the daily working Design, setting participants In context multicentre case–control study, we collected data from 505 women with surgically/histologically confirmed diagnosis matched controls. Study were recruited prospectively in hospitals doctors’...

10.1136/bmjopen-2017-019570 article EN cc-by-nc BMJ Open 2019-01-01

Cardiovascular diseases are strongly influenced by stress and do share several risk factors with hypertensive in pregnancy (HDP). The aim of the study is to investigate correlation between emotional during for HDP.A self-administered questionnaire comprising obstetrical psychosocial questions was completed 725 patients 880 controls matched age, parity, nationality, educational level.Emotional associated a 1.6-fold increased HDP.Psychosocial interventions reduce may help decrease develop HDP.

10.1080/10641950701274870 article EN Hypertension in Pregnancy 2007-01-01
Coming Soon ...