A5101618686- Extracellular vesicles in disease
- Nanoplatforms for cancer theranostics
- Nanopore and Nanochannel Transport Studies
- MicroRNA in disease regulation
- Solar-Powered Water Purification Methods
- RNA Interference and Gene Delivery
- Anodic Oxide Films and Nanostructures
- Electrospun Nanofibers in Biomedical Applications
- Dendrimers and Hyperbranched Polymers
- Cell Adhesion Molecules Research
- Advanced biosensing and bioanalysis techniques
- MXene and MAX Phase Materials
- ZnO doping and properties
- Membrane Separation Technologies
Soochow University
2021-2025
Extracellular vesicles (EVs) are nanoparticles secreted by cells with a closed phospholipid bilayer structure, which can participate in various physiological and pathological processes have significant clinical value disease diagnosis, targeted therapy prognosis assessment. EV isolation methods currently include differential ultracentrifugation, ultrafiltration, size exclusion chromatography, immunoaffinity, polymer co-precipitation microfluidics. In addition, material-based biochemical or...
Extracellular vesicles (EVs) and their cargoes are increasingly being recognized as noninvasive diagnostic markers, necessitating the isolation of EVs from complex biological samples. Herein, a distearoyl phospholipid ethanolamine-functionalized single-crystal ordered macroporous three-dimensional zeolitic imidazolate framework (SOM-ZIF-8-DSPE) was developed, which combines surface charge interaction ZIF-8 with synergistic effect DSPE insertion into membrane to improve isolating selectivity...
As cell secretions, exosomes play an important role in disease diagnosis, but the extraction of high-purity from body fluids faces great challenges. To address this issue, work creates excellently selective adsorbent by modifying zwitterionic polymer carrying choline phosphate on surface honeycomb-shaped supermacroporous silica, which integrates chemisorption and size-exclusion principles. The results indicate that supermacropore with a thin pore wall allows to enter thereby be adsorbed via...
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