Kaimin Guo

ORCID: 0000-0003-4061-7067
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About
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Research Areas
  • Laser-induced spectroscopy and plasma
  • Laser-Matter Interactions and Applications
  • Analytical chemistry methods development
  • Mass Spectrometry Techniques and Applications
  • Laser Material Processing Techniques
  • Advanced Fiber Laser Technologies
  • Mercury impact and mitigation studies
  • Cancer, Lipids, and Metabolism
  • Advanced Chemical Physics Studies
  • Nonmelanoma Skin Cancer Studies
  • interferon and immune responses
  • High Temperature Alloys and Creep
  • Cultural Heritage Materials Analysis
  • Laser Design and Applications
  • Orbital Angular Momentum in Optics
  • Geophysics and Gravity Measurements
  • RNA regulation and disease
  • Lipid metabolism and disorders
  • Trauma and Emergency Care Studies
  • Ion-surface interactions and analysis
  • Tumors and Oncological Cases
  • Simulation-Based Education in Healthcare
  • Angiogenesis and VEGF in Cancer
  • Maternal and fetal healthcare
  • Pulsars and Gravitational Waves Research

Guangzhou Medical University
2025

Beihang University
2023

First Hospital of Jilin University
2023

Jilin University
2023

Institute of Hematology & Blood Diseases Hospital
2022

Chinese Academy of Medical Sciences & Peking Union Medical College
2022

Baotou Teachers College
2019-2022

Changchun University of Science and Technology
2011-2013

Abstract Enhancer deregulation is a well-established pro-tumorigenic mechanism but whether it plays regulatory role in tumor immunity largely unknown. Here, we demonstrate that cell ablation of mixed-lineage leukemia 3 and 4 (MLL3 MLL4, also known as KMT2C KMT2D, respectively), two enhancer-associated histone H3 lysine (H3K4) mono-methyltransferases, increases immunogenicity promotes anti-tumor T response. Mechanistically, MLL4 attenuates the expression RNA-induced silencing complex (RISC)...

10.1038/s41467-022-34253-1 article EN cc-by Nature Communications 2022-11-02

Abstract During uterine spiral artery remodeling, vascular smooth muscle cells (VSMCs) become disorganized and undergo phenotypic switching from a contractile to more synthetic phenotype. We have previously reported that natural killer induce this VSMC by secreting angiopoietin‐2 (Ang‐2). Here, we identified the specific mechanisms which Ang‐2 plays role in phenomenon. VSMCs isolated human umbilical arteries were used as an vitro model investigate of switching. Human decidua tissue...

10.1096/fj.202402754r article EN The FASEB Journal 2025-03-03

Increasing sample temperature is an effective method for improving emission intensity of laser-induced breakdown spectroscopy (LIBS). An increase in the requires only simple modification to LIBS system, and does not require pretreatment. In addition, formation decay plasma (LIP) are a dynamic physical process. Time-resolved can enrich information data dimension. The further analysis time-resolved has potential understand this study, beam nanosecond laser was used excite brass produce plasma....

10.1063/1.5097301 article EN cc-by AIP Advances 2019-06-01

The abilities to trigger and guide high-voltage discharge by using single multiple filaments (MFs) are experimentally studied. It is shown that the voltage threshold can be reduced significantly in both regimes of MF; however, MF does not gain a larger reduction than filament. This behavior attributed path rather simultaneous ones as one might expect during process.

10.1364/ol.37.000259 article EN Optics Letters 2012-01-13

We report on the observation of dual-pulses laser-produced plasmas (DP-LPPs), following a femtosecond Ti: sapphire pulse laser ablate soil generated substantial number aerosol particle clusters target and then nanosecond Nd:YAG re-ablated particles clusters. The temporal evolution fs (fs-LPPs) highlight different in plasma plume expansion dynamics distributions where, initial position velocity are 0.79 mm 4.8 km/s, terminal is 2.2 gradually become slower slower, delay time range 150 ns to...

10.1016/j.rinp.2020.103601 article EN cc-by-nc-nd Results in Physics 2020-11-20

The time- and space-resolved optical emission spectra (OES) of Si plasma produced by femtosecond laser pulse with center wavelength 800 nm width 100 fs in air were investigated. results show that the OES mainly consist continuous spectrum at early stage expansion (within first 50 ns), then weakens gradually while line becomes dominating. existence time ion is shorter than atomic process plume expansion. red-shift, which has a second order exponential decay delay time, been found...

10.7498/aps.60.025203 article EN cc-by Acta Physica Sinica 2011-01-01

Modulating the length and position of plasma filament is desired for many filament-based applications. We proposed a novel method to manipulate properties along propagation direction by introducing asymmetric focusing with wedge plate in forced region. By simply varying inclination degree distance between lens, can break into two sub-filaments direction, separation be controlled. The experiment results are agreement simulation ray-tracing method. Furthermore, effect angle rotation on control...

10.1063/5.0073278 article EN Physics of Plasmas 2022-01-01

A comparative investigation of the resistance and ability to trigger high voltage (HV) discharge for a single filament (SF) multiple filaments (MFs) has been carried out. The experimental results show that trend breakdown threshold SF exactly follows its resistance, but this is not case MF. MF's much smaller than SF's. However, MF shows slightly higher HV SF. underlying physics measured collectively contributed by every in while determined only one discharging path.

10.1088/1674-1056/22/3/035203 article EN Chinese Physics B 2013-03-01

Abstract Objects on the earth are subject to gravity due universal gravitation. This paper systematically studies influence factors, including latitude, altitude, depth inside earth, surrounding stars, gravitational acceleration of object near earth. The results show that latitude has a relatively large impact acceleration; and altitude have greatest acceleration. orbit position (dayside or nightside earth) little effect object. Our work can offer reference for accurate calculation

10.1088/1742-6596/1865/2/022014 article EN Journal of Physics Conference Series 2021-04-01

Electric conductivity and high voltage breakdown threshold of single plasma filament generated by femtosecond laser are spatio resolved measured. The results show that the resistance is in a range 280630 kcm after eliminating contact resistance, can be reduced down to ~50% original value air. Furthermore, variations discharge follow same trend as for part filament. relation between established.

10.7498/aps.60.105203 article EN cc-by Acta Physica Sinica 2011-01-01

Effects of focusing conditions on femtosecond laser induced plasma fluorescence in air are investigated by using different focal length lenses. Under the tightly condition, spectra composed mainly continuous spectrum and line from N O atoms, which is due to higher intensity corresponding electron density than those case weakly focused beam. In latter case, only molecules observed. Besides, as a function propagation distance measured, reveals evolution filaments.

10.7498/aps.61.075212 article EN cc-by Acta Physica Sinica 2012-01-01

Simulation-based training in obstetrical emergencies can effectively reduce related adverse maternal-fetal outcomes by enhancing clinical comprehensive skills and confidence of obstetricians, improving the team communicational ability. However, effect simulation-based will fade out as time goes by. Therefore, should be used regularly repeatedly emergencies, such shoulder dystocia, umbilical cord prolapse, postpartum hemorrhage eclampsia. Key words: Patient simulation; Shoulder...

10.3877/cma.j.issn.2095-3259.2016.04.004 article EN Chin J Obstet Emerg(Electronic Edition) 2016-11-18
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