A5030817396- Dialysis and Renal Disease Management
- Dermatology and Skin Diseases
- Sinusitis and nasal conditions
- Renal Diseases and Glomerulopathies
- Inflammatory Biomarkers in Disease Prognosis
- Genomics, phytochemicals, and oxidative stress
- Web Applications and Data Management
- Endoplasmic Reticulum Stress and Disease
- Voice and Speech Disorders
- Aortic aneurysm repair treatments
- Renin-Angiotensin System Studies
- Mast cells and histamine
- Head and Neck Surgical Oncology
- Venomous Animal Envenomation and Studies
- Receptor Mechanisms and Signaling
- Vitamin D Research Studies
- Cell Adhesion Molecules Research
- Obstructive Sleep Apnea Research
- Vestibular and auditory disorders
- Fungal Infections and Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Blood properties and coagulation
- Monoclonal and Polyclonal Antibodies Research
- Psoriasis: Treatment and Pathogenesis
- Ocular Infections and Treatments
Gachon University Gil Medical Center
2020-2022
Gachon University
2021
Eulji University
2015-2019
Eulji University Hospital
2013-2017
Asan Medical Center
2012
University of Ulsan
2012
Epithelial-to-mesenchymal transition (EMT) is thought to play a significant role in the advancement chronic kidney disease and contributes deposition of extracellular matrix proteins renal fibrosis relating diabetic nephropathy. We studied effect Nrf2-HO-1 signaling on high-glucose- (HG-) induced EMT normal human tubular epithelial cells, that is, HK2 cells. In short, we treated cells with HG sulforaphane (SFN) as an Nrf2 activator. was evaluated by expression activity marker E-cadherin...
<b><i>Background:</i></b> Endoplasmic reticulum (ER) stress induced by urinary albumin plays an important role in tubulointerstitial injury. We have shown that albumin-induced ER is regulated through reactive oxygen species (ROS)-c-Src kinase-mTOR signaling pathways. postulated peroxisome proliferator-activated receptor-γ (PPAR-γ) might also act as upstream molecule between c-Src kinase and mTOR. It has been suggested AMP-activated protein (AMPK) involved attenuation...
<i>Background/Aims:</i> Desmopressin decreases bleeding time in uremic patients. Although is the most frequently used measure of global platelet function, this test has important disadvantages. In vitro closure (CT) a relatively new and efficient primary hemostasis. We designed prospective randomized study to evaluate effect desmopressin on as measured by CT, <i>Methods:</i> Forty-eight patients, about commence hemodialysis with prolonged were infusion (n = 24) or...
Abstract Chronic kidney disease‐associated pruritus ( CKD ‐ aP ) is a troublesome symptom in patients with end‐stage renal disease ESRD ). Recently, vitamin D deficiency has been known to be one of the possible etiologic factors . However, limited data available on whether topical treatment effective for relieving Therefore, purpose this study evaluate effectiveness topically Twenty‐three were enrolled single center, open‐label study. Patients instructed apply (calcipotriol) agent (Daivonex...
Endothelin-1 (ET-1) promotes atherosclerosis. We tested whether spleen tyrosine kinase (Syk) mediates tumor necrosis factor-α (TNF-α)-induced ET-1 upregulation in human aortic endothelial cells (HAECs) and sought to identify the signal pathways involved. TNF-α-induced reactive oxygen species (ROS) activated Syk phosphatidylinositol 3-kinase (PI3K), which was required for activation of AP-1 subsequent gene transcription. ROS mediated c-Jun NH(2)-terminal (JNK) is also activation, but PI3K...
Korean red ginseng (KRG) has been traditionally used in Korea for health improvement. However, the clinical effect of KRG intake on symptoms patients with allergic rhinitis remains unknown. Our study was performed to identify effects and examine inflammatory reaction. We evaluated 60 rhinitis. All were treated 4 weeks. The divided into 3 groups, according medication. Twenty KRG, 20 placebo, antihistamine. recorded their a daily symptom diary card. checked peak nasal inspiratory flow rate 2...
A 58-yr-old man presented with leg edema and subacute weakness of his bilateral lower extremities. Urinary serum immunoelectrophoresis revealed the presence lambda-type Bence Jones proteins. He was ultimately diagnosed monoclonal gammopathy undetermined significance (MGUS). renal biopsy specimen showed fibrillary glomerulonephritis (FGN), which randomly arranged as 12-20 m nonbranching fibrils in basement membranes. Immunofluorescence studies were negative for immunoglobulin (Ig)G, IgM, IgA,...
Orbital apex syndrome (OAS) is a rare condition that usually occurs due to damage surrounding inner and bone tissue. may result from variety of conditions cause the superior orbital fissure optic canal leading nerve (II) dysfunction. We recently experienced case sphenoidal Aspergillosis, which damaged adjacent cavernous sinus structures led definite symptom bilateral OAS in 77-year-old male. present this with brief review these disease's entities.
Microscopic polyangiitis (MPA) is an idiopathic autoimmune disease characterized by systemic vasculitis associated with antineutrophil cytoplasmic autoantibodies. Interstitial lung a less recognized manifestation of MPA and has poor prognosis. A 61-year-old man presented persistent cough, sputum dyspnea. Laboratory examination revealed microscopic hematuria renal insufficiency. Perinuclear anti-neutrophil autoantibodies were positive according to serological testing. Computed tomography...
Nephrotic syndrome is characterized by hypercoagulability and thrombosis of the renal deep veins.We describe a case unusual in portal superior mesenteric veins 41-year-old female, admitted for treatment abdominal pain, who simultaneously presented with nephrotic acute pancreatitis.Laboratory analysis revealed hypoalbuminemia, hyperlipidemia, proteinuria.Abdominal computed tomography pancreatitis, at veins, ischemic changes colon small intestines.Anticoagulation therapy was started...
A 38-year-old man was admitted to the hospital because of abrupt left flank pain. He had no fever and physical examination revealed tenderness costovertebral angle. Laboratory data white blood cell 16,060/μL, C-reactive protein 0.93 mg/dL. Urinalysis showed more than 1/2 red cells per high-power field with severe proteinuria (4+). Enhanced computed tomography (CT) thickened abdominal aorta wall partial thrombus. The compressed renal vein it caused thrombosis. Abdominal CT findings suggested...
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A 35-year-old man presented with progressive dyspnea and hemoptysis. His blood pressure was 230/140 mmHg serum creatinine level 20.13 mg/dL. Chest radiography computed tomography revealed pulmonary hemorrhage. renal function low, thus emergent replacement therapy required. Malignant hypertension acute kidney injury were diagnosed, antihypertensive hemodialysis started immediately. Renal biopsy performed to examine the underlying disease. Typical pathological changes of malignant...
Morganella morganii (M. Morganii) is a Gram-negative rod that part of the normal flora in humans. However, M. Morganii rare cause PD-related peritonitis. A 78-year-old woman with end-stage renal disease secondary to diabetes mellitus on Automated Peritoneal Dialysis (PD) admitted abdominal pain and cloudy peritoneal fluid. After performing fluid culture, patient was treated intraperitoneal (IP) antibiotics. On hospital day 4, culture revealed Morgani. Although IP antibiotics injection had...
Rhino-orbito-cerebral mucormycosis (ROCM) is an invasive fungal infection that usually occurs in immunocompromised patients. It aggressive and has a high risk of mortality. With unclear guidelines, ROCM treated various ways. We present patient who underwent kidney transplant for without major complications.
Background and Objectives Vocal process granulomas (VPGs) are benign lesions of the larynx, typically contact (CG) intubation (IG). The two diseases known to have different clinical manifestations despite having same pathological features. purpose this study was analyze treatment results for CG IG obtain information.Materials Method We retrospectively reviewed medical records patients diagnosed with VPG between January 2015 December 2018. patient’s age, sex, history, lesion size, type,...