A5087827579- Bariatric Surgery and Outcomes
- Elasticity and Material Modeling
- Gastroesophageal reflux and treatments
- Gastrointestinal motility and disorders
- Gastric Cancer Management and Outcomes
- Electrospun Nanofibers in Biomedical Applications
- Mechanical Engineering and Vibrations Research
- Orthopaedic implants and arthroplasty
- Tissue Engineering and Regenerative Medicine
- Lower Extremity Biomechanics and Pathologies
- Cardiac, Anesthesia and Surgical Outcomes
- Urological Disorders and Treatments
- Medical Imaging Techniques and Applications
- Urinary Bladder and Prostate Research
- Colorectal Cancer Surgical Treatments
- Pelvic floor disorders treatments
- Intraocular Surgery and Lenses
- Polysaccharides Composition and Applications
- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Radiomics and Machine Learning in Medical Imaging
- Sports injuries and prevention
- Medical Image Segmentation Techniques
- Bone health and osteoporosis research
- Food composition and properties
University of Padua
2019-2024
Scuola Superiore Sant'Anna
2020
Bladder cancer (BC) is among the most common malignancies in world and a relevant cause of mortality. BC one frequent causes for bladder removal through radical cystectomy, gold-standard treatment localized muscle-invasive some cases high-risk, non-muscle-invasive cancer. In order to restore urinary functionality, an autologous intestinal segment has be used create diversion. However, several complications are associated with bowel-tract removal, affecting patients’ quality life. The present...
Abstract Background Obesity has become a global epidemic. Bariatric surgery is considered the most effective therapeutic weapon in terms of weight loss and improvement quality life comorbidities. Laparoscopic sleeve gastrectomy (LSG) one performed procedures worldwide, although patients carry nonnegligible risk developing post-operative GERD BE. Objectives The aim this work development computational patient-specific models to analyze changes induced by bariatric surgery, i.e., volumetric...
Gastro-oesophageal reflux disease (GERD) consists in the passage of gastric acid content from stomach to oesophagus, causing burns and deteriorating quality life. Laparoscopic Sleeve Gastrectomy (LSG) could induce de novo GERD worsen pre-existing because higher pressurisation, reduction volume a wider His-angle. In proposed work, various computational 2D models were developed understand effects variables such as His-angle, antral dimension, bolus viscosity on increase.Fluid-Structure...
Within the framework of computational biomechanics, finite element models gastric district could be seen as a potential clinical tool not only to study effects apported by bariatric surgery, but also compare different surgical techniques such new emerging Endoscopic Sleeve Gastroplasty (ESG) with respect well-established ones (such Laparoscopic Gastrectomy, LSG).This work realized fully comparison between outcomes obtained from 10 patient-specific stomach models, which were used simulate...
Abstract The suprapatellar fat pad is an adipose tissue located in the anterior knee whose role osteoarthritis still debated. Considering that anatomy drives function, aim of this histotopographic study was to investigate specific morphological features versus infrapatellar absence osteoarthritis, for a broad comparative analysis. Suprapatellar and samples ( n = 10/group) underwent microscopical/immunohistochemical staining transmission electron microscopy analysis; thus, tissue‐specific...
Abstract LSG is one of the most performed bariatric procedures worldwide. It a safe and effective operation with low complication rate. Unsatisfactory weight loss/regain may occur, suggesting that design could be improved. A bioengineering approach might significantly help in avoiding common complications. Computational models sleeved stomach after were developed according to bougie size (range 27–54 Fr). The endoluminal pressure basal volume computed at different intragastric pressures. At...
Background: The stomach is a hollow organ of the gastrointestinal tract, on which bariatric surgery (BS) performed for treatment obesity. Even though BS most effective severe obesity, drawbacks and complications are still present because intervention design largely based surgeon’s expertise intraoperative decisions. Bioengineering methods can be exploited to develop computational tools more rational presurgical planning intervention. Methods: A mechanical model was developed, considering...
Introduction: Clinics increasingly require readily deployable tubular substitutes to restore the functionality of structures like ureters and blood vessels. Despite extensive exploration various materials, both synthetic biological, optimal solution remains elusive. Drawing on abundant literature experiences, there is a pressing demand for substitute that not only emulates native tissue by providing requisite signals growth factors but also exhibits appropriate mechanical resilience...
The mechanical characterization of adipose tissues is important for various medical purposes, including plastic surgery and biomechanical applications, such as computational human body models the simulation surgical procedures or injury prediction, example, in evaluation vehicle crashworthiness. In this context, measurement subcutaneous tissue (SAT) visceral (VAT) properties relation to subject characteristics may be really relevant. aim work was properly characterize response patients with...
Abstract Ski boots are known to cause vasoconstriction in the wearer’s lower limbs and, thus, a “cold leg” phenomenon. To address this problem, work provides computational framework for analysing interactions between ski boot and limb. The geometry of limb was derived from magnetic resonance imaging computed tomography techniques anthropometric data. shell obtained by means three-dimensional computer aided design models manufacturer. Concerning liner, laser scanning were implemented capture...
The relatively recent adoption of Endoscopic Sleeve Gastroplasty (ESG) amongst obese patients has gained approval within the surgical community due to its notable benefits, including significant weight loss, safety, feasibility, repeatability, and potential reversibility. However, despite promising clinical outcomes reduced invasiveness, there is still a lack standardised procedures for performing ESG. Multiple suture patterns stitching methods have been proposed over time, yet rational...
Abstract Objectives To analyse and compare the functionality of extraluminal intraluminal artificial urinary sphincters (AUSs), an in silico procedure has been defined applied. Design reliability assessments AUS are typically performed using a clinical approach, which does not provide data on mechanical stimulation urethral tissues. Mechanical may determine tissue degeneration, such as atrophy or erosion, main causes failure. In techniques can quantitative description stress strain fields...