A5008855269- Photoreceptor and optogenetics research
- Analytical Chemistry and Sensors
- Conducting polymers and applications
- Electrochemical sensors and biosensors
- Advanced Memory and Neural Computing
- Neuroscience and Neural Engineering
- Nanocomposite Films for Food Packaging
- Electrochemical Analysis and Applications
- Power Transformer Diagnostics and Insulation
- Advanced Battery Materials and Technologies
- Neural dynamics and brain function
- High voltage insulation and dielectric phenomena
- melanin and skin pigmentation
- Extraction and Separation Processes
- Additive Manufacturing and 3D Printing Technologies
- Organic Chemistry Cycloaddition Reactions
- Eicosanoids and Hypertension Pharmacology
- Bee Products Chemical Analysis
- Power Systems Fault Detection
- Silk-based biomaterials and applications
- HIV Research and Treatment
- Lignin and Wood Chemistry
- Power System Reliability and Maintenance
- Insect and Pesticide Research
- Sensor Technology and Measurement Systems
The First People's Hospital of Shunde
2019-2022
Southern Medical University
2019-2022
Chongqing University
2020
University of Washington
2011-2017
California Institute of Technology
2017
Seattle University
2011-2015
The electrical properties of eumelanin, a ubiquitous natural pigment, have fascinated scientists since the late 1960s. For several decades, hydration-dependent eumelanin mainly been interpreted within amorphous semiconductor model. Recent works undermined this paradigm. Here we study protonic and electronic charge carrier transport in hydrated thin film form. Thin films are ideal candidates for these studies they readily accessible to chemical morphological characterization potentially...
Abstract Breathalyzers estimate Blood Alcohol Content (BAC) from the concentration of ethanol in breath. are easy to use but limited either by their high price and environmental concerns, or a short lifetime need for continuous recalibration. Here, we demonstrate proof-of-concept disposable breathalyzer using an organic electrochemical transistor (OECT) modified with alcohol dehydrogenase (ADH) as sensor. The OECT is made conducting polymer...
Proton conduction is essential in biological systems. Oxidative phosphorylation mitochondria, proton pumping bacteriorhodopsin and uncoupling membrane potentials by the antibiotic Gramicidin are examples. In these systems, H+ hop along chains of hydrogen bonds between water molecules hydrophilic residues – wires. These wires also support transport OH− as holes. Discriminating has been elusive. Here, achieved polysaccharide- based devices. A H+- junction with rectifying behaviour H+-type...
In 1678, Stefano Lorenzini first described a network of organs unknown function in the torpedo ray-the ampullae (AoL). An individual ampulla consists pore on skin that is open to environment, canal containing jelly and leading an alveolus with series electrosensing cells. The role AoL remained mystery for almost 300 years until research demonstrated skates, sharks, rays detect very weak electric fields produced by potential prey. likely contributes this function, yet exact details...
Two-terminal protonic devices with PdHx proton conducting contacts and a Nafion channel achieve 25 ms spiking, short term depression, low-energy memory switching. With the recent physical demonstration of memristive-based devices,1, 2 low-power two terminal learning functions3 have advanced electronics neuromorphic computing.4-9 In computing, CMOS transistor circuits10-12 are designed to mimic architectures in brain synaptic connections between neurons whose conductivity is influenced by...
A chitin nanofiber ink affords facile fabrication of macro- and nanostructures through airbrushing, replica molding, microcontact printing. Self-assembled structures with sub 50 nm features are produced on extended areas. Detailed facts importance to specialist readers published as "Supporting Information". Such documents peer-reviewed, but not copy-edited or typeset. They made available submitted by the authors. Please note: The publisher is responsible for content functionality any...
We highlight our recent efforts in developing devices that control the flow of H<sup>+</sup> and OH<sup>−</sup> biological polymers.
Translating ionic currents into measureable electronic signals is essential for the integration of bioelectronic devices with biological systems. We demonstrate use a Pd/PdHx electrode as bioprotonic transducer that connects H+ in solution an signal. This exploits reversible formation PdHx according to PdH↔Pd + e−, and dependence this on pH applied potential. integrate protonic glucose dehydrogenase enzymatic gate NAD+. associated current monitors output drop pH, thus transducing function...
This paper focuses on the in-depth analysis of physical mechanism broadband frequency domain spectroscopy oil-paper insulation. The complex permittivity shows two low-frequency dispersion phenomena, and real part conductivity exhibits slope changes under synergistic effect aging moisture. are mainly attributed to migration characteristics water molecules polar products with a degradation insulation, resulting in transition dependence between DC AC conductivity. When insulation deteriorates...
Epilepsy encompasses a group of heterogeneous brain diseases that afflict about 1% the world's population. Accumulating evidence shows immune system plays key role in epileptogenesis. Nevertheless, immune-related mechanisms remain not been precisely understood.Three epilepsy datasets (GSE16969, GSE32534 and GSE143272) were screened to obtain differentially expressed genes (DEIRGs). Random forest (RF) protein-protein interaction (PPI) network constructed identify core genes. Another dataset...
The synthesis of a positively charged and water soluble chitosan derivative from is presented.
In Nature, protons (H(+)) can mediate metabolic process through enzymatic reactions. Examples include glucose oxidation with dehydrogenase to regulate blood level, alcohol dissolution into carboxylic acid dehydrogenase, and voltage-regulated H(+) channels activating bioluminescence in firefly jellyfish. Artificial devices that control currents concentration (pH) are able actively influence biochemical processes. Here, we demonstrate a biotransducer monitors regulates pH-responsive reactions...
Advancing electronic devices that interface with biology will require a thorough understanding of the electrochemical pathways transduce currents into ionic currents.
Charge transfer at the interface between active layer and contact is essential in any device. Transfer of electronic charges across contact/active with metal contacts well-understood. To this end, noble metals, such as gold or platinum, are widely used. With these contacts, ionic currents (especially protonic) often neglected because ions protons do not layer. Palladium hydride have emerged good to measure proton a reversible redox reaction subsequent absorption/desorption H into palladium,...
In this work, the extended Debye model or Fourier transform is adopted to convert polarization and depolarization current test results from time domain into frequency at low frequencies, thereby shortening but producing large errors when oil-paper insulation exhibits nonlinear characteristics. The voltage-current response characteristics of samples with three different moisture contents are tested study influence on Hammerstein-Wiener (H-W) equivalent mathematical proposed for time-frequency...
Self-assembled chitin nanofibers are microcontact printed onto a glass substrate. Ultrafine self-assemble from hexafluoro-2-propanol solution upon drying. On page 4776, Marco Rolandi and co-workers use this “chitin nanofiber ink” for airbrushing, replica molding, micro-contact printing of structures across length scales. Notably, sub-35 nm features achieved.