A5081391670- Cardiac Imaging and Diagnostics
- Cardiovascular Health and Disease Prevention
- Cerebrovascular and Carotid Artery Diseases
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Function and Risk Factors
- Blood Pressure and Hypertension Studies
- Cardiac Ischemia and Reperfusion
- Infective Endocarditis Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Disease and Adiposity
- Coronary Interventions and Diagnostics
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Lipoproteins and Cardiovascular Health
- Cardiac pacing and defibrillation studies
- Blood groups and transfusion
- Cardiac Health and Mental Health
- Diabetes and associated disorders
- Medication Adherence and Compliance
- Atrial Fibrillation Management and Outcomes
- Heart Rate Variability and Autonomic Control
- Peripheral Artery Disease Management
- Cardiac tumors and thrombi
Umeå University
2016-2025
Västerbotten County
2013-2015
Heart Foundation
2013-2015
Creative Commons
2014
Swedish Heart-Lung Foundation
2013
University Hospital of Umeå
1986-2002
Hennepin County Medical Center
2000
University of Lübeck
2000
University of Minnesota
2000
Mayo Clinic
2000
Aims In transthyretin amyloid (ATTR) amyloidosis various principal phenotypes have been described: cardiac, neuropathic, or a mixed cardiac and neuropathic. addition, two different types of fibrils identified (type A type B). Type B thus far only found in predominantly early-onset V30M patients carrying the Y114C mutation, whereas is noted all other mutations currently examined as well wild-type ATTR amyloidosis. The fibril determinant disease phenotype. (99m)Tc-DPD scintigraphy highly...
Aortic stenosis (AS) has no approved medical treatment. Identifying etiological pathways for AS could identify pharmacological targets.To novel genetic loci and associated with AS.This genome-wide association study used a case-control design to evaluate 44 703 participants (3469 cases of AS) self-reported European ancestry from the Genetic Epidemiology Research on Adult Health Aging (GERA) cohort (from January 1, 1996, December 31, 2015). Replication was performed in 7 other cohorts totaling...
Non-adherence to guidelines and preventive measures is a major challenge, particularly so obtain long-term adherence lifestyle changes recommended medication. The objective was investigate if pictorial information regarding subclinical carotid atherosclerosis provided individuals physicians gave sustained effects on cardiovascular risk beyond the previously reported effect after 1 year up 3 years.A Prospective Randomized Open Blinded End-point (PROBE) trial. Within CVD prevention program in...
Sweden has an ambitious plan to fully decarbonise district heating by 2030 and contribute with negative emissions of greenhouse gases in 2050. The vagaries the energy market associated climate, political, social changes entail cross-sectoral integration that can fulfill these national targets. Fifth-generation cooling (5GDHC) is a relatively new concept systems features simultaneous supply using power-to-heat technologies. This paper presents best practices for developing 5GDHC reach...
The registration of non-fatal and fatal MI events initiated 1985 in the WHO MONICA project has been ongoing northern Sweden since end 1995. purpose present study was to analyze gender differences first recurrent events, case fatality mortality myocardial infarction (MI) Northern during 20-year period – 2004. Diagnosed subjects aged 25–64 years Counties Norrbotten Västerbotten were validated according protocol. total number registered up January 1, 2005 11,763: 9,387 men 2,376 women....
There is conflicting and only scant evidence on the effect of gender long-term survival after a myocardial infarction (MI). Our aim was to analyse sex-specific patients for up 23 years first MI in northern Sweden describe time trends.The Northern MONICA Myocardial Infarction Registry linked The Swedish National Cause Death total 8630 patients, 25 64 age, 6762 men 1868 women, with during 1985-2006. Also deaths before admission hospital were included. Follow-up ended August 30, 2008.Median...
Abstract Background The ABO blood group system has shown an association with cardiovascular disease. susceptibility to CVD is proposed be partly mediated by dyslipidaemia in non-O individuals. Previous studies are scarce for the RhD group, but we recently showed that − young individuals associated subclinical atherosclerosis. Hence, sought examine whether groups and factor dyslipidaemia. Methods All participants were part of VIPVIZA study, including 3532 available plasma lipid levels. Lipids...
This study aimed to assess the early effect of trans-catheter aortic valve implantation (TAVI) on right (RV) and left ventricular (LV) function in severe stenosis (AS) patients. Twenty AS patients (age 79±6 years) were examined before, one week six weeks after TAVI using Doppler echocardiography. LV ejection fraction (EF), long-axis [mitral annular plane systolic excursion (MAPSE)] RV [tricuspid (TAPSE)] function, septal radial motion studied. Results compared with 30 before replacement...
Reperfusion therapy reduces both morbidity and mortality in myocardial infarction, but the effectiveness depends on how fast patient receives treatment. Despite time-dependent of reperfusion therapy, many patients with infarction have delays seeking medical care. The aim this study was to describe pre-hospital delay a first among men women without diabetes association between time diabetes, sex, age, symptoms size residential area as proxy for distance hospital. This population based data...
Background Aortic stenosis ( AS ) has different clinical phenotypes, including with or without concomitant coronary artery disease CAD ). It is unknown whether these phenotypes share the same risk factors. In particular, lipoprotein(a) [Lp(a)] and apolipoproteins (Apo) are associated , but it associations differ among phenotypes. this prospective analysis we examined impact of Lp(a) Apo in subgroups patients . Methods Results We identified 336 (mean age at survey 56.7 years, 48% female) who...
Aims Health literacy, the degree to which individuals understand and act upon health information, may have a pivotal role in prevention of cardiovascular disease (CVD), with low literacy potentially explaining poorer adherence guidelines. We investigated associations between ultrasound-detected carotid atherosclerosis risk factors. Methods Baseline data (cross-sectional analysis) from randomized controlled trial, integrated within Västerbotten Intervention Program, Northern Sweden, was used....
Cardiovascular disease is a common cause of morbidity and premature mortality. can be prevented when risk factors are identified early. Calcified carotid artery atheromas (CCAAs), detected in panoramic radiographs, periodontitis have both been associated with increased cardiovascular disease. This case-control study aimed to 1) investigate associations between CCAA radiographs 2) determine the future myocardial infarctions due combined periodontitis. We evaluated 1,482 participants (738...
Abstract Objectives We examined the magnitude of transcription errors in lipid variables VIPVIZA study and assessed whether education among research personnel reduced error frequency at follow-up. also how affected SCORE2 risk prediction algorithm for cardiovascular disease, which includes parameters, as this could lead to an incorrect treatment decision. Methods The assessment where results total cholesterol, triglycerides, HDL calculated LDL cholesterol are transcribed into database by...
The role of cognitive abilities in the development arteriosclerotic disease is still not fully understood. purpose present study was to evaluate mediating lifestyle, socioeconomic status (SES) and conventional cardiovascular (CVD) risk factors association between ability at age 19 subclinical atherosclerosis 60 years. An observational design employed. Data on results from tests conscripts tested were collected for 1009 men. At 60, they included trial VIsualiZation asymptomatic...