(2<i>S</i>)-2-[(Phenylsulfinyl)methyl]pyrrolidine, derived from <sc>l</sc>-proline, has been demonstrated as an efficient organocatalyst for the asymmetric Michael addition of cyclohexanone and cyclopentanone to β-nitrostyrenes. This pyrrolidine-based catalyst bearing a sulfoxide moiety was used synthesize various γ-nitro carbonyl compounds in high yield (up 97%) with excellent ste­reoselectivity >99:1 dr >99% ee) without use any additive.

Carbon–carbon and carbon–heteroatom bond construction through oxidative carbon–hydrogen activation has attracted much attention in synthetic organic chemistry. Recently, a variety of reactions inactivated cyclic ethers (THF, THP dioxane) acyclic with various coupling partners have been reported. Despite the absence phenyl rings high oxidation potentials, these worked efficiently under conditions. This review focusses on recent reports C–C C–heteroatom formation cross dehydrogenative coupling.

In recent years, reactions of inexpensive and easily available formamides, benzaldehydes cycloalkanes with various coupling partners have made an impact in the field cross dehydrogenative coupling. Even absence a benzylic C–H site or heteroatom at α‐position, these substrates react efficiently under oxidative conditions. This review article highlights advances for C–C C–heteroatom bond formation above substrates.

The present research study analyzes the impact of social media on society and governance. phenomenal growth platforms like Facebook, Twitter, Instragram, Buffer, LinkedIn, Blog other multifaceted tools are proving to be a double edged sword in functioning democracies across world. While one hand it has democratized access information communication technology also thrown up new challenges which now directly impacting society, democracy India's total population was 1.42 billion January, 2023....

When considering the effect of commercialization on media performance, journalistic content and role play in providing information a democratic society. There is always comparison to be made between current commercialized system an alternative politically controlled mostly India. Commercialization has resulted homogenization news, cementing capitalist society, reduction quality sensationalizing or trivializing news depoliticizing news. debate as whether these factors combine mean damaged...

The NEP 2020 was approved by the Union Cabinet of India on 29 July, 2020. Ministry Human Resource Development formed a committee headed former ISRO Chairman Dr K Kasturirangan, who outlined vision India's new education system. New Education Policy addresses challenges faced current system such as Quality, Affordability, Equity, Access and Accountability. envisions an India-centric that contributes directly to transforming our nation sustainably into equitable vibrant society filled knowledge...

Journal Article Heterodimeric DNA-binding dyes designed for energy transfer: synthesis and spectroscopic properties Get access Scott C. Benson, Benson Department of Molecular Cell Biology, 229 Stanley Hall, University CaliforniaBerkeley,CA 94720, USA Search other works by this author on: Oxford Academic PubMed Google Scholar Paramjit Singh, Singh Alexander N. Glazer ′ * To whom correspondence should be addressed Nucleic Acids Research, Volume 21, Issue 24, 11 December 1993, Pages 5727–5735,...

Metallation of BF3–pyridine complex with lithium tetramethylpiperidide (LTMP) in ether at –78 °C, followed by reaction carbonyl compounds, affords α-pyridyl alcohols good yields.

S. V. Kessar, P. Singh, R. Vohra, N. Kaur and K. J. Chem. Soc., Commun., 1991, 568 DOI: 10.1039/C39910000568

Direct cross-coupling between N-methyltetrahydroisoquinolines and alkynes using CuI-DEAD is presented. It affords the regioselective C-1-alkynylated products in good yield. This regio­selectivity contrast to results reported earlier reaction of N,N-dimethylbenzyl amine where N-methyl alkynylated product was formed exclusively or predominantly. The C-1-substituted propargylic isoquinolines were easily reduced phenethylisoquinolines with Pd/C. sequence provides a short route synthesize...

A simple protocol for the C1 arylation of tetrahydroisoquinolines with aryl Grignard reagents via diethyl azodicarboxylate (DEAD) mediated oxidative C–H activation under metal-free conditions has been developed. The target compounds, including some naturally occurring alkaloids, were obtained in moderate to good yields.

Director's cut: The poor directing ability of the dimethylamino group in directed ortho metalation is altered by complexation to BF3, which makes it more strongly activating than methoxy and chloro groups. DFT calculations simplified lithiated intermediates reveal a small role inductive effect, but distinctive F⋅⋅⋅Li interaction that leads F–Li distance remarkably similar C–Li distance.