A5085053040- Cardiac Imaging and Diagnostics
- Advanced X-ray and CT Imaging
- Coronary Interventions and Diagnostics
- Advanced MRI Techniques and Applications
- Cardiovascular Disease and Adiposity
- Radiation Dose and Imaging
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Coronary Artery Anomalies
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Arrhythmias and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Electrical and Bioimpedance Tomography
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Aortic Thrombus and Embolism
- Cardiovascular Issues in Pregnancy
- Cardiac tumors and thrombi
- Peroxisome Proliferator-Activated Receptors
- Salivary Gland Tumors Diagnosis and Treatment
- Cardiac Structural Anomalies and Repair
- Lipid metabolism and biosynthesis
- Cardiac Ischemia and Reperfusion
- Medical Imaging Techniques and Applications
Juntendo University
2016-2025
Juntendo University Urayasu Hospital
2023-2024
RIKEN Center for Biosystems Dynamics Research
2024
RELX Group (United States)
2018
London Borough of Camden
2018
Juntendo University Hospital
2017
Toshiba (Japan)
2017
Icahn School of Medicine at Mount Sinai
2013
Takara (Japan)
2013
Toho University
2010-2011
Although deep-learning algorithms have been used to compute fractional flow reserve (FFR) from coronary computed tomography angiography (CCTA), no study has achieved 'fully automated' (i.e. free human input) FFR calculation using algorithms. The purpose of the was evaluate accuracy a fully automated 3D model for estimating minimum CCTA data, with invasive as reference standard. This retrospective 1052 patients included 131 whose studies showed 30–90% stenosis and underwent (abnormal observed...
We evaluated diagnostic accuracy of CT-fractional flow reserve (CT-FFR) computed on-site with a new vendor workstation, against invasive FFR as the reference standard.Retrospective analyses compared CT-FFR 104 vessels 30-90% diameter stenosis in 75 patients imaged using single-rotation 320 detector-row coronary CT angiography (CCTA) performed within 90 days. Prospective ECG-gated CCTA included exposure 70-99% R-R interval. was same physical space scanner and reading room. The >50% ≤0.8 to...
Coronary computed tomography angiography (CCTA) not only provides information regarding luminal stenoses but also allows for visualization of mural atheromatous changes (coronary plaques).We sought to elucidate whether plaques seen on CCTA enable prediction 2-year outcomes in patients with suspected and known coronary artery disease (CAD).Of 3015 who underwent CCTA, the images clinical courses 2802 were independently analyzed. The primary endpoint was composite all-cause death acute...
Aim: Coronary computed tomography angiography (CCTA) findings of positive remodeling (index >1.1) and low-attenuation plaque (<30 Hounsfield units) are recognized as CT-verified high-risk (CT-HRP). Therefore, we investigated the incremental prognostic value evaluation characteristics using CCTA in asymptomatic patients.
Background: Recent development of multi-detector computed tomography (MDCT) has made the detection myocardial bridge (MB) easier on left anterior descending coronary artery (LAD). The LAD segment proximal to MB is well known be susceptible atherosclerosis. Anatomical characteristics in patients with infarction (MI) were examined by MDCT. Methods and Results: Subjects 43 MI who had comprised 2 groups: 14 culprit lesions (culprit group) 29 without (non-culprit group). length, thickness,...
Objective The aim of this study was to evaluate the reproducibility computed tomography (CT)–derived fractional flow reserve (FFR) determined on site by inexperienced observers using a postprocessing software based structural and fluid analysis. Methods Using 21 coronary vessels in 7 patients who underwent 320-row CT angiography catheter-FFR, 2 independent (A: student radiation technologist; B: nonmedical staff) CT-FFR software. After 20-minute training session, both postprocessed all...
Purpose To investigate whether vorticity could predict functional plaque progression better than high-risk (HRP) and lesion length (LL) in individuals with type 2 diabetes mellitus. Materials Methods This single-center prospective study included 61 participants (mean age, years ± 9 [SD]; 43 male participants) who underwent serial coronary CT angiography at years, 20%–70% stenosis initial between October 2015 March 2020. The number of the following HRP characteristics was recorded: low...
Cardiac events after revascularization are equally attributable to recurrence at site of culprit lesions and development nonculprit lesions. We evaluated the hypothesis that coronary computed tomography (CT) angiography artery calcium score (CACS) performed before predicts cardiac treatment.Among 2238 consecutive patients without known disease who underwent CT CACS, 359 within 30 days CT; in 337 (93.9%) follow-up clinical information was available. In addition risk factors, findings were as...
Computed tomography fractional flow reserve (CT-FFR), which can be acquired on-site workstation using fluid structure interaction during the multiple optimal diastolic phase, has an incremental diagnostic value over conventional coronary computed angiography (CCTA). However, appropriate location for CT-FFR measurement remains to clarified. A total of 115 consecutive patients with 149 vessels who underwent CCTA showing 30–90% stenosis invasive FFR within 90 days were retrospectively analyzed....
Whether malnutrition during the early phase of recovery from acute myocardial infarction (AMI) could be a predictor mortality or morbidity has not been ascertained. We examined 289 AMI patients. All-cause and composite endpoints (all-cause mortality, nonfatal stroke, coronary syndrome, hospitalization for decompensated heart failure) follow-up duration (median 39 months) were evaluated. There 108 (37.8%) malnourished patients with GNRIs less than 98 on arrival; however, significantly...
Abstract Aims To develop an artificial intelligence (AI)-model which enables fully automated accurate quantification of coronary artery calcium (CAC), using deep learning (DL) on electrocardiogram (ECG)-gated non-contrast cardiac computed tomography (gated CCT) images. Methods and results Retrospectively, 560 gated CCT images (including 60 synthetic images) performed at our institution were used to train AI-model, can automatically divide heart region into five areas belonging left main...
The incremental prognostic value of the plaque features in coronary computed tomographic angiography (CTA) has not been well assessed. This study was designed to determine whether CTA high-risk plaques have Framingham risk score (FRS) and severity luminal obstruction.A total 628 newly symptomatic patients without known artery disease underwent CTA. They were followed for a median 677 days during which there 26 cardiac events, including death, acute myocardial infarction, hospitalization...
AimsRecent study suggests that algorithms such as the Duke Clinical score (DCS) may overestimate pretest probability. The Agatston representing grade of coronary artery calcification can be simply calculated from low-radiation exposure ECG-gated plain CT. In this study, we investigated whether or not more superior diagnostic performance for obstructive disease (CAD) obtained by combining DCS with score.
Although on-site workstation-based CT fractional flow reserve (CT-FFR) is an emerging method for assessing vessel-specific ischemia in coronary artery disease, severe calcification a significant factor affecting CT-FFR's diagnostic performance. The subtraction significantly improves the value with respect to anatomic stenosis patients angiography (CCTA). We evaluated capability of CT-FFR using (subtraction CT-FFR) calcification. This study included 32 45 lesions (Agatston score >400) who...
Abstract Background Leiomyosarcoma occurring as a primary cardiac tumor has been known an extremely rare condition. Previous studies of leiomyosarcoma with rhabdomyoblastic differentiation have conducted to those arisen from another site, and they indicated poorer prognosis this tumor. Case presentation A 69-year-old woman was referred our hospital for operation concerning umbilical hernia. Subsequent imaging examinations before the presence malignant due its atypical shape. And then, it...