A5035169133- Wound Healing and Treatments
- Mesenchymal stem cell research
- Seaweed-derived Bioactive Compounds
- Pluripotent Stem Cells Research
- Nanoplatforms for cancer theranostics
- Echinoderm biology and ecology
- Hair Growth and Disorders
- Marine and coastal plant biology
- Graphene and Nanomaterials Applications
- Infective Endocarditis Diagnosis and Management
- Silk-based biomaterials and applications
- Mycobacterium research and diagnosis
- Hemostasis and retained surgical items
- FOXO transcription factor regulation
- Polyamine Metabolism and Applications
- Phytase and its Applications
- Histone Deacetylase Inhibitors Research
- Marine Bivalve and Aquaculture Studies
- Surgical Sutures and Adhesives
- Polymer Surface Interaction Studies
- Electrospun Nanofibers in Biomedical Applications
- Antimicrobial Peptides and Activities
- Kruppel-like factors research
- Bacterial Identification and Susceptibility Testing
- Diabetic Foot Ulcer Assessment and Management
Southwest Hospital
2020-2024
Dalian Polytechnic University
2023-2024
Army Medical University
2020-2024
Donghua University
2024
Nanjing Second Hospital
2024
University of Manitoba
2020-2021
Burn Institute
2021
Southwest General Health Center
2021
Chongqing University
2021
Bioadhesives reduce operation time and surgical complications. However, in the presence of blood, adhesion strength is often compromised. Inspired by blood clotting activity snake venom, we report a visible light-induced blood-resistant hemostatic adhesive (HAD) containing gelatin methacryloyl reptilase, which hemocoagulase (HC) extracted from Bothrops atrox HAD leads to activation aggregation platelets efficiently transforms fibrinogen into fibrin achieve rapid hemostasis seal tissue. Blood...
Abstract The successful reprogramming of impaired wound healing presents ongoing challenges due to the tissue microenvironment caused by severe bacterial infection, excessive oxidative stress, as well inappropriate dosage timing during different stages process. Herein, a dual-layer hydrogel with sodium alginate (SA)-loaded zinc oxide (ZnO) nanoparticles and poly(N-isopropylacrylamide) (PNIPAM)-loaded Cu 5.4 O ultrasmall nanozymes (named programmed time-released multifunctional hydrogel,...
An antibacterial moisture balanced dressing is designed to fight infection and promote wound healing.
Objective Diagnosing tuberculosis (TB) can be particularly challenging in the absence of sputum for pulmonary cases and extrapulmonary TB (EPTB). This study evaluated utility nanopore-based targeted next-generation sequencing (tNGS) diagnosing tissue samples, compared its efficacy with other established diagnostic methods. Methods A total 110 samples from clinical were examined. The sensitivity specificity tNGS benchmarked against a range existing approaches including hematoxylin eosin (HE)...
Epidermal stem cells (EpSCs) can self-renew, which are responsible for the long-term maintenance of skin, and it also plays a critical role in wound re-epithelization, but mechanism underlying EpSCs proliferation is unclear. GDF-5, known as BMP-14, member BMP family be used self-renewal supporter. Here, we studied effects GDF-5 on mouse healing.
Abstract Background Cell therapy is a key technology to prevent sacrificing normal skin. Although some studies have shown the promise of human epidermal stem cells (EpiSCs), efficacy, biosafety and quality control EpiSC not been systematically reported. Methods The biosafety, stemness maintenance wound repair were verified by in vitro vivo experiments. prepared from foreskin using collagen type IV rapid adherence method. EpiSCs identified flow cytometry, immunofluorescence staining cell...
Abstract The migration of epidermal stem cells (EpSCs) is critical for wound re‐epithelization and healing. Recently, growth/differentiation factor‐5 (GDF‐5) was discovered to have multiple biological effects on healing; however, its role in EpSCs remains unclear. In this work, recombinant mouse GDF‐5 (rmGDF‐5) found via live imaging vitro facilitate the a wound‐scratch model. Western blot real‐time PCR assays demonstrated that expression levels RhoA matrix metalloproteinase‐9 (MMP9) were...
Abstract Background: Cell therapy is a key technology to prevent sacrificing normal skin. Although some studies have shown the promise of human epidermal stem cells (EpiSCs), efficacy, biosafety and quality control EpiSC not been systematically reported. Methods: The biosafety, stemness maintenance wound repair were verified by in vitro vivo experiments. prepared from foreskin using collagen type IV rapid adherence method. EpiSCs identified flow cytometry, immunofluorescence staining cell...