A5076201518- Pluripotent Stem Cells Research
- Renal and related cancers
- CRISPR and Genetic Engineering
- RNA Interference and Gene Delivery
- Immune Response and Inflammation
- Modular Robots and Swarm Intelligence
- Reproductive Biology and Fertility
- Single-cell and spatial transcriptomics
- Antimicrobial Peptides and Activities
University of Colorado Boulder
2023
Colorado Center for Reproductive Medicine
2023
Inner Mongolia Medical University
2023
Recent advances in human blastoids have opened new avenues for modeling early development and implantation. One limitation of our first protocol blastoid generation was relatively low efficiency. We now report an optimized the efficient large quantities high-fidelity from naive pluripotent stem cells. This enabled proteomics analysis that identified phosphosite-specific signatures potentially involved derivation and/or maintenance signaling states blastoids. Additionally, we uncovered...