A5043485555- Colorectal Cancer Surgical Treatments
- Diabetes Management and Research
- Diabetes and associated disorders
- Colorectal and Anal Carcinomas
- Diet, Metabolism, and Disease
- Diet and metabolism studies
- Sexual Differentiation and Disorders
- Vitamin D Research Studies
- Obesity, Physical Activity, Diet
- Hypothalamic control of reproductive hormones
- Growth Hormone and Insulin-like Growth Factors
- Gastric Cancer Management and Outcomes
- Birth, Development, and Health
- Colorectal Cancer Treatments and Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Liver Disease Diagnosis and Treatment
- Lipid metabolism and disorders
- Bone health and osteoporosis research
- Colorectal Cancer Screening and Detection
- Genetic factors in colorectal cancer
- Hormonal and reproductive studies
- Pancreatic function and diabetes
- Vitamin C and Antioxidants Research
- Parathyroid Disorders and Treatments
- Nutrition, Health and Food Behavior
Catholic Kwandong University
2022-2024
International St. Mary's Hospital
2022-2024
Yonsei University
2000-2023
Sejong University
2023
Severance Hospital
2018-2022
Pusan National University Yangsan Hospital
2022
Gangnam Severance Hospital
2021
Ewha Womans University
2013-2014
National Cancer Center
2005-2012
National Cancer Center
2010
It is critical that the risk of lymph node metastasis (LNM) evaluated for determining suitability endoscopic resection T1 colorectal cancer (CRC). Reported factors LNM in completely resected CRC are deep submucosal invasion, grade 3, angiolymphatic and budding. The aim present study was to identify histopathologic associated with CRC.The involved 435 patients treated by or surgical between January 2001 April 2010 at National Cancer Center, Korea. were classified into two groups - those...
We investigated the modified triglycerides-glucose (TyG) indices and other markers for non-alcoholic fatty liver disease (NAFLD) in 225 participants aged 10-19 years, were divided into subgroups according to their NAFLD grade. performed logistic regression analysis calculated odds ratios (ORs) with 95% confidence intervals (CIs) of tertiles 2 3 each parameter, those tertile 1 as a reference. The area under receiver operating characteristic (ROC) curve was compare parameters identifying...
The incidence of type 1 diabetes mellitus (T1DM) among children is high in Europe and the USA relatively low Asia, including Korea. present study aimed to investigate prevalence childhood-onset T1DM Korea examine trends incidence.
The triglyceride glucose (TyG) index, derived from a combination of fasting and triglycerides, has been suggested as useful marker for insulin resistance (IR), in addition to modified TyG indices that combine obesity parameters. This study investigated the association utility IR prediction youth. Based on Korea National Health Nutritional Examination Survey, data 3728 youth aged 10–19 years were analyzed. Odds ratios (ORs) 95% confidence intervals (CIs) tertiles 2 3 each parameter calculated...
Investigations on the trends of prediabetes and non-alcoholic fatty liver disease (NAFLD) among children are scarce. We aimed to analyze NAFLD, as well their association, Korean adolescents from 2009 2018. This study investigated prevalence prediabetes, abdominal obesity 6327 aged 10-18 years according age, sex, body mass index (BMI) using a nationally representative survey. The increased 5.14%, 8.17%, 5.97% respectively, in 10.46%, 12.05%, 10.51% In age-specific analyses, an adverse trend...
Purpose: Metabolic syndrome (MetS) comprises a cluster of risk factors for future cardiovascular and metabolic diseases.Only few recent studies have reported the trend in prevalence MetS youth.This study aimed to analyze trends nutrient intake last 10 years investigate changes components among Korean children adolescents.Materials Methods: We analyzed data 9513 adolescents aged 10-19 from 2008-2017 National Health Nutrition Examination Surveys.Diagnosis was based on International Diabetes...
Discontinuing growth hormone (GH) treatment during the transition to adulthood has been associated with adverse health outcomes in patients childhood-onset deficiency (CO-GHD). This study investigated metabolic changes interrupting GH adolescents CO-GHD period.This included 187 who were confirmed have adult GHD and treated at six academic centers Korea. Data on clinical parameters, including anthropometric measurements, profiles, bone mineral density (BMD) end of childhood treatment,...
The effects of 3, 3', 5-triiodothyronine (T3) on 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity were evaluated in the C100 baby hamster kidney cell line. Cells cultured Minimal Essential Medium (MEM) supplemented with 10% thyroid hormone-depleted fetal bovine serum (THDS-MEM) and had a 70.1% lower level HMG-CoA than cells grown medium (FBS). When T3 was added to THDS-MEM, reduction blocked dose-dependent manner. In THDS-MEM for 48 hours, (10-6 M) treatment rapidly...
Phosphate is essential in regulating human metabolic processes, and severe hypophosphatemia can induce neurologic hematological complications result respiratory failure cardiac dysfunction. Therefore, correction of be pivotal the management diabetic ketoacidosis (DKA). We report case a 14-year-old female who was diagnosed with type 1 diabetes referred to our institute for treatment DKA. Although patient received fluid continuous insulin administration according current DKA protocol,...
Purpose Hypothermia at admission is associated with increased mortality and morbidity in preterm infants. We performed a quality improvement (QI) effort to determine the impact of decrease hypothermia Methods The study enrolled very low birth weight (VLBW) infants born Gangnam Severance Hospital between January 2013 December 2016. This multidisciplinary QI included use occlusive wraps, warm blankets, caps; delivery room temperature was maintained above 23.0˚C, check-list used for feedback....
To investigate the long-term outcomes of selected patients with cT3 distal rectal cancer treated local excision following pre-operative chemoradiotherapy. Between January 2003 and February 2008, 11 received a The median age was 61 years (range, 42–71). tumor size 3 cm 2–5), distance caudal edge from anal verge 1–4). Clinical lymph node status positive in five patients. Pre-operative chemoradiotherapy consisted 50.4 Gy 28 fractions concurrent chemotherapy. A transanal full-thickness performed...
A few studies have reported a positive association between phthalate exposure and pubertal timing, but several conflicting reports exist. The main objective of the study was to determine whether associated with central precocious puberty in girls. This multicenter case-control wherein 47 girls (CPP) controls (26 pre-pubertal 21 girls) were enrolled. No obese included. Five metabolites (creatinine adjusted) bisphenol (BPA) measured first spot urine samples these 94 early morning. median...
Dyslipidemia is one of the important influencing factors cardiovascular health in youth, and thus, assessment its etiology important. We aimed to investigate association dyslipidemia with vitamin D physical activity Korean children adolescents. Data 3183 subjects aged 12-18 years Korea National Health Nutrition Examination Survey were analyzed. Participants divided into subgroups according sex, body mass index, 25-hydroxyvitamin levels, lipid profile. The mean level was 16.15 ng/mL, which...
The appropriate evaluation of height and accurate estimation bone age are crucial for proper assessment the growth status a child. We developed program using deep learning algorithm established model to predict final adult Korean children.A total 1678 radiographs from 866 children, which interpretation results were consistent between two pediatric endocrinologists, used train validate model. was based on convolutional neural network system. test set simulation performed by raters 150 data...
C-peptide is conventionally used in assessing pancreatic function patients with diabetes mellitus. The clinical significance of this molecule during the course type 1 mellitus (T1DM) has been recently revisited. This study aimed to investigate natural T1DM over period 15 years and analyze association between residual complications.This retrospective included a total 234 children adolescents T1DM. Patient data including sex, age at diagnosis, anthropometric measures, daily insulin dose, serum...
Nonambulatory pediatric patients may have low bone mineral density (BMD) and increased risk of pathologic fractures. Though bisphosphonate therapy is the mainstream medical intervention in these children, clinical data regarding this treatment are limited. Therefore, study aimed to evaluate effectiveness safety such children.