Multiple sclerosis (MS) is a neurologic disease of the central nervous system which affects almost three million people worldwide. MS characterized by demyelination process that leads to brain lesions, allowing these affected areas be visualized with magnetic resonance imaging (MRI). Deep learning techniques, especially computational algorithms based on convolutional neural networks (CNNs), have become frequently used algorithm performs feature self-learning and enables segmentation...

The imbalance in the concentration of metallic nanoparticles has been demonstrated to play an important role multiple sclerosis (MS), which may impact cognition. Biomarkers are needed provide insights into pathogenesis and diagnosis MS. They can be used gain a better understanding cognitive decline people with MS (pwMS). In this study, we investigated relationship between blood (blood nanoparticles) performance pwMS. First, four mL samples, clinical characteristics, were obtained from 21 All...

It is estimated that multiple sclerosis (MS) affects 35,000 Brazilians and 2.5 million individuals worldwide. Many studies have suggested a possible role of metallic elements in the etiology MS, but their concentration blood MS patients nonetheless little investigated Brazil. In this work, these were studied through Inductively Coupled Plasma Mass Spectrometry (ICP-MS), whose analysis provides tool to quantify concentrations metal samples with neurodegenerative disorders. This study aimed...

The purpose of this work was to develop a quantitative method for evaluating the pulmonary inflammatory process (PIP) through computational analysis chest radiography exams in posteroanterior (PA) and lateral views. quantification procedure applied patients with tuberculosis (TB) as motivating application. A study high-resolution computed tomography (HRCT) examinations TB developed establish relation between signal difference-to-noise ratio (SDNR) measured PA projection. phantom essay used...

This study presents methodology for objectively quantifying the pulmonary region affected by emphysemic and fibrotic sequelae in treated patients with paracoccidioidomycosis. may also be applied to any other disease that results these lungs. Pulmonary high-resolution computed tomography examinations of 30 paracoccidioidomycosis were used study. The distribution voxel attenuation coefficients was analyzed determine percentage lung volume consisted emphysemic, fibrotic, normal tissue....

Background: Tuberculosis (TB) is an infectious lung disease with high worldwide incidence that severely compromises the quality of life in affected individuals. Clinical tests are currently employed to monitor pulmonary status and treatment progression. The present study aimed apply a three-dimensional (3D) reconstruction method based on chest radiography quantify lung-involvement volume TB acute-phase patients before after treatment. In addition, these results were compared indices from...

Magnetic resonance imaging (MRI) is the most commonly used exam for diagnosis and follow-up of neurodegenerative diseases, such as multiple sclerosis (MS). MS a neuroinflammatory disease characterized by demyelination neuron axon. This process causes lesions in white matter that can be observed vivo MRI. Such may provide quantitative assessments inflammatory activity disease. Quantitative measures based on various features have been shown to useful clinical trials evaluating therapies....

Introdução: O uso da Classificação Internacional de Funcionalidade, Incapacidade e Saúde (CIF) por fisioterapeutas tem o intuito tornar a avaliação tratamento mais abrangente; determinado como enfoque funcionalidade humana Modelo Biopsicossocial. Objetivo: Elaborar validar manual prático para utilização CIF ferramenta guiar diagnóstico cinético funcional profissionais fisioterapia na área traumato-ortopedia reumatologia. Métodos: Estudo validação conteúdo semântica com amostra 10 juízes. Foi...

O objetivo deste foi avaliar o nível de aprendizado ciências dos discentes do ensino médio, através da associação conhecimentos etnobotânicos e cotidiano familiar, utilizando jardim sensorial como espaço não-formal inclusão social. Foram investigadas as relações familiares no tocante medicina popular resgate saberes passados geração para geração, repensando práticas sociais papel sujeito núcleo familiar mediador, transmissor agente transformador conhecimento. Demostrou-se ser essencial...

Recent studies have focused on the link between metals and neurodegenerative diseases like multiple sclerosis (MS), particularly emphasizing role of copper (Cu). Essential for vital functions, Cu imbalances can contribute to MS-related neurodegeneration cerebral lesions. Interestingly, accumulation could be a potential biomarker in magnetic resonance image (MRI) MS. This study aimed obtain copper(I) oxide nanoparticles (Cu2O-NPs) evaluate their effectiveness MRI as contrast agents or MS...

Raman spectroscopy is a promising analytical technique for characterizing kidney stones, allowing precise identification of their components and non-destructive analysis. In this study, stone was characterized using micro-Raman at wavelength 532 nm, prototype sample holder to optimize measurements avoid damaging the confocal microscope lens.

Magnetic resonance imaging (MRI) is critical in the diagnosis of neurodegenerative diseases, enabling detection brain lesions. Recent research has examined metallic nanoparticles (NPs) as MRI contrast agents (CAs) that can enhance lesion visibility by altering relaxation times. This study investigates effects metal oxide NPs on times and signals proposes an algorithm for automated time determination using these NPs. The utilized were synthesized sol‒gel method characterized Fourier-transform...

A tomografia computadorizada de alta resolucao se tornou o exame diagnostico por imagem mais utilizado para avaliacao das sequelas da Paracoccidioidomicose. As avaliacoes subjetivas anormalidades radiologicas encontradas nas imagens TCAR nao proporcionam uma quantificacao acurada. O auxiliado sistemas computacionais produzem objetiva dos padroes anormais encontrados TCAR. Desse modo, nesta pesquisa propos-se desenvolvimento algoritmos em ambiente computacional Matlab®, capaz quantificar...

The aim of this study was to compare two ways measuring the resolution limit radiographic systems, one subjective and quantitative. To end, nine images were acquired with different techniques using a pattern bars aluminum plates. With these modulation transfer function (MTF) through edge image obtained by plate — MTF 10% measured on all images — variation points, which faced evaluation standard bar. Although we have observed greater between measurements bar-pattern, simplicity technique...

Multiple Sclerosis (MS) is a chronic and inflammatory disorder that causes degeneration of axons in brain white matter spinal cord. Magnetic Resonance Imaging (MRI) extensively used to identify MS lesions evaluate the progression disease, but manual identification quantification are time consuming error-prone tasks. Thus, automated Deep Learning methods, special Convolutional Neural Networks (CNNs), becoming popular segment medical images. It has been noticed performance those methods tends...

The objective of this letter is to provide a perspective on the impact multiple sclerosis (MS) postural control and gait suggestions for future studies. Although studies MS with have been carried out some time, in Brazil World, there still insufficient information impairments gait.Postural are recognized cause several problems people MS, these being two symptoms that most affect quality life.Here, we present investigated using different experimental designs discuss adaptations central...