- Ultrasound and Hyperthermia Applications
- Cardiac Arrhythmias and Treatments
- Thermoelastic and Magnetoelastic Phenomena
- Architecture and Art History Studies
- Architecture, Art, Education
- Cardiac electrophysiology and arrhythmias
- Microbial Inactivation Methods
- Higher Education Teaching and Evaluation
- Architecture and Computational Design
- Atrial Fibrillation Management and Outcomes
- Thyroid and Parathyroid Surgery
- Advanced MRI Techniques and Applications
- Microfluidic and Bio-sensing Technologies
- Educational Technology in Learning
- Hepatocellular Carcinoma Treatment and Prognosis
- Photoacoustic and Ultrasonic Imaging
- Wireless Power Transfer Systems
- Advanced Thermodynamics and Statistical Mechanics
- Ocular and Laser Science Research
- Business, Education, Mathematics Research
- Heat Transfer Mechanisms
- Thermoregulation and physiological responses
- Infrared Thermography in Medicine
- Nanofluid Flow and Heat Transfer
- Laser Material Processing Techniques
Universitat Politècnica de València
2015-2024
Polytechnic University of Puerto Rico
2020
Instituto Colombiano del Petróleo y Energías de la Transición - Icpet
2018
Ecopetrol (Colombia)
2018
Universidad de Oriente
2015
Instituto Politécnico Nacional
2012
Abstract Microwave (MWA) and radiofrequency ablation (RFA) are main ablative techniques for hepatocellular carcinoma (HCC) colorectal liver metastasis (MT). This randomized phase 2 clinical trial compares the effectiveness of MWA RFA as well morphology corresponding zones. HCC MT patients with 1.5–4 cm tumors, suitable ablation, were into or Groups. The primary endpoint was short-to-long diameter ratio zone (SLR). Primary technical success (TS) a cumulative local tumor progression (LTP)...
Abstract The objective of this study was to compare three different heat transfer models for radiofrequency ablation in vivo liver tissue using a cooled electrode and voltage levels. comparison between the simplest but less realistic Pennes’ equation two porous media-based models, i.e. Local Thermal Non-Equilibrium (LTNE) equations Equilibrium (LTE) equation, both modified take into account two-phase water vaporization (tissue blood). Different blood volume fractions were considered velocity...
Purpose: To study the relationship between roll-off (sudden increase in impedance) and spatial distribution of dehydrated tissue during RF ablation using a cooled electrode (temperatures around 100°C).Methods: We used double approach: (1) theoretical modelling based on finite element method, (2) 20 ablations an experimental ex vivo excised bovine liver which we measured impedance progress temperature at three points close to surface: 0.5 (T1), 1.5 (T2) 2.5 (T3) mm from tip. T2 was located...
To develop computer models to mimic the impedance-controlled pulsing protocol implemented in radiofrequency (RF) generators used for clinical practice of ablation (RFA), and assess appropriateness by comparing results with those obtained previous experimental studies.A 12-min RFA was modelled using a cooled electrode (17G, 3 cm tip) inserted hepatic tissue. The short (transverse) diameter coagulation zone assessed under vivo (with blood perfusion (BP) considering clamping) ex (at 21 °C)...
The aim of this study was to compare the efficacy bipolar (BM) vs. unipolar (UM) mode radiofrequency ablation (RFA) in terms creating transmural lesions across interventricular septum (IVS) and ventricular free wall (VFW).We built computational models temperature distributions lesion dimensions created by BM UM on IVS VFW during RFA. Two different types were considered: sequential (SeUM) simultaneous (SiUM). effect thickness, catheter misalignment, epicardial fat, presence air space also...
Abstract Irreversible electroporation is a fast-growing liver ablation technique. Although safety has been well documented in small ablations, our aim to assess its and feasibility when large portion of ablated. Eighty-seven mice were subjected high voltage pulses directly delivered across parallel plate electrodes comprising around 40% mouse liver. One group consisted 55 athymic-nude, which tumor from the KM12C cell line was grown other thirty-two C57-Bl6 non-tumoral mice. Both groups...
To improve the computer modelling of radiofrequency ablation (RFA) by internally cooled wet (ICW) electrodes with added clinically oriented features.An improved RFA model ICW electrode included: (1) a realistic spatial distribution infused saline, and (2) different domains to distinguish between healthy tissue, saline-infused tumour, non-infused under assumption that saline is retained within tumour boundary. A was obtained from an in vivo pig liver study. The results were analysed terms...
To date, all radiofrequency heating (RFH) theoretical models have employed Fourier's heat transfer equation (FHTE), which assumes infinite thermal energy propagation speed. Although this is probably suitable for modeling most RFH techniques, it may not be so surgical procedures in very short times are employed. In such cases, a non-Fourier model should considered by using the hyperbolic (HHTE). Our aim was to compare temperature profiles obtained from FHTE and HHTE modeling. We built...
We describe the periodic solutions and study chaotic behavior of solution semigroup a Cauchy problem corresponding to hyperbolic heat transfer equation.
The thermal and electrical effects of pulsed radiofrequency (PRF) for pain relief can be controlled by modifying the characteristics RF pulses applied. Our goal was to evaluate influence such modifications on electric performance in tissue.A computational model developed compare temperature field time courses tissue between a standard clinical protocol (45 V pulses, 20 ms duration, 2 Hz repetition frequency) new (55 5 with higher applied but smaller impact alterations tissue. effect...
Theoretical modeling is a technique widely used to study the electrical-thermal performance of different surgical procedures based on tissue heating by use radiofrequency (RF) currents. Most models employ parabolic heat transfer equation (PHTE) Fourier's theory, which assumes an infinite propagation speed thermal energy. We recently proposed one-dimensional model in coupled problem was analytically solved using hyperbolic (HHTE), i.e. considering non zero relaxation time. In this study, we...
(1) To analyse rehydration, thermal convection and increased electrical conductivity as the three phenomena which distinguish performance of internally cooled electrodes (IC) wet (ICW) during radiofrequency ablation (RFA), (2) Implement a RFA computer model with an ICW includes these (3) Assess their relative influence on tissue response coagulation zone size.A 12-min in liver was modelled using electrode (17 G, 3 cm tip) by impedance-control pulsing protocol constant current 1.5 A. A IC...
Purpose To study the differences between continuous and short-pulse mode microwave ablation (MWA).Methods We built a computational model for MWA including 200 mm long 14 G antenna from Amica-Gen solved an electromagnetic-thermal coupled problem using COMSOL Multiphysics. compared coagulation zone (CZ) sizes created with pulsed modes under ex vivo in conditions. The was used to compare vs. short pulses, 1000 W high-powered pulses. Ex experiments were conducted validate model.Results models...
Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation Lorena Atares, Maria Jose Canet, Macarena Trujillo, Javier Paricio; The First Step to Address the Teaching of Entropy. Phys. Teach. 1 April 2024; 62 (4): 287–289. https://doi.org/10.1119/5.0135846 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex...
The alternative conceptions that students hold put a brake on subsequent meaningful learning, and therefore, the identification of these wrong ideas is crucial for effective teaching academic success. Undergraduate STEM often perceive Chemical Thermodynamics as difficult subject, in which entropy has been pointed out threshold concept. In this paper, prevalence two about first-year undergraduate studied by analyzing quantitative qualitative results before after instruction. It was found...
Journal Article Analytical thermal–optic model for laser heating of biological tissue using the hyperbolic heat transfer equation Get access Macarena Trujillo, Trujillo † Departamento de Matemática Aplicada, Instituto Universitario Pura y Universidad Politécnica Valencia, Camino Vera s/n, 46022 Spain †Email: matrugui@mat.upv.es Search other works by this author on: Oxford Academic Google Scholar María J. Rivera, Rivera Juan A. López Molina, Molina Enrique Berjano Institute Research and...
The objectives of this study were to model the temperature progress a pulsed radiofrequency (RF) power during RF heating biological tissue, and employ hyperbolic heat transfer equation (HHTE), which takes thermal wave behavior into account, compare results those obtained using based on Fourier theory (FHTE). A theoretical was built an active spherical electrode completely embedded in after HHTE FHTE analytically solved. We found three typical waveforms for depending relations between...
Purpose: To assess by means of computer simulations whether the heat sink effect inside a large vessel (portal vein) could protect wall from thermal damage close to an internally cooled electrode during radiofrequency (RF)‐assisted resection. Methods: First, in vivo experiments were conducted validate computational model comparing experimental and lesion shapes created around vessels. Computer then carried out study different factors such as device‐tissue contact, position, vessel‐device...
The Hyperbolic Heat Transfer Equation describes heat processes in which extremelyshort periods of time or extreme temperature gradients are involved.It is already known that there solutions this equation exhibit a chaotic behaviour, the sense Devaney,on certain spaces analytic functions with growth control.We show behaviour still appears when we add source term to equation, i.e. Bioheat Equation.These results can also be applied for Wave and higher order version Equation.
Externally irrigated radiofrequency (RF) electrodes have been widely used to thermally ablate tumors in surface tissue and coagulate the transection plane during a surgical resection. As far as we know, no mathematical model has yet developed study electrical thermal performance of these electrodes, especially role saline layer that forms around electrode. Numerical models TissueLink device DS3.0 (Salient Surgical Technologies, Portsmouth, NH, USA) were developed. Irrigation was modeled...