A5057347250- Bone fractures and treatments
- Hip and Femur Fractures
- Orthopedic Surgery and Rehabilitation
- Shoulder Injury and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Shoulder and Clavicle Injuries
- Musculoskeletal pain and rehabilitation
- Trauma and Emergency Care Studies
- Muscle and Compartmental Disorders
- Osteoarthritis Treatment and Mechanisms
- Ultrasound in Clinical Applications
- Knee injuries and reconstruction techniques
- Vector-borne infectious diseases
- Total Knee Arthroplasty Outcomes
- Viral Infections and Vectors
- European and International Law Studies
- Trauma Management and Diagnosis
- Nutrition and Health in Aging
- Electrolyte and hormonal disorders
- Foot and Ankle Surgery
- Research in Social Sciences
- Electroconvulsive Therapy Studies
- Sports injuries and prevention
- Tendon Structure and Treatment
- Lower Extremity Biomechanics and Pathologies
Helsinki University Hospital
2017-2025
University of Helsinki
2001-2025
Töölö Hospital
2019-2021
Faculty (United Kingdom)
2021
Orthopaedic Trauma Association
2021
<h3>Importance</h3> Humeral shaft fractures traditionally have been treated nonsurgically, but there has a steady increase in the rate of surgery over past 2 decades without high-quality evidence to justify trend. <h3>Objective</h3> To compare effectiveness surgical treatment with open reduction and internal plate fixation nonsurgical functional bracing closed humeral fractures. <h3>Design, Setting, Participants</h3> Randomized clinical trial conducted at university hospital trauma centers...
ABSTRACT The most characteristic features of the Lyme disease pathogens, Borrelia burgdorferi sensu lato (s.l.) group, are their ability to invade tissues and circumvent immune defenses host for extended periods time, despite elevated levels borrelia-specific antibodies in serum other body fluids. Our aim present study was determine whether B. is able interfere with complement (C) at level C3 by accelerating C3b inactivation thus inhibit amplification C cascade. Strains belonging different...
Background Functional orthoses offer comparable outcomes to traditional casting in function and symptom relief after ankle fracture surgery, with the potential benefit of improved patient comfort mobility. Even though early functional treatment surgery shows promise, uncertainties about outcomes, relief, wound complications remain. Questions/purposes (1) Are 12 weeks injury patients treated bracing (2 cast immobilization followed by 4 bracing) superior those who undergo 6 surgery? (2) 2...
<h3>Importance</h3> Existing evidence indicates that surgery fails to provide superior functional outcome over nonoperative care in patients with a closed humeral shaft fracture. However, up one-third of treated nonoperatively may require secondary surgery. <h3>Objective</h3> To compare the 2-year outcomes who required successful initial treatment. <h3>Design, Setting, and Participants</h3> This follow-up Finnish Shaft Humerus (FISH) randomized clinical trial comparing treatment (functional...
Introduction Humeral shaft fractures represent 1%–3% of all and 20% humeral in adults. The treatment these is mainly conservative operative usually reserved for specific circumstances. To date, no randomised controlled trial (RCT) has compared with treatment. Methods analysis We will conduct an RCT to compare the effectiveness cost-effectiveness surgical fractures. After providing informed consent, 80 patients from 18 years age fracture be randomly assigned open reduction internal fixation...
Several previously identified patient-, injury-, and treatment-related factors are associated with the development of nonunion in distal femur fractures. However, predictive value these is not well defined. We aimed to assess ability risk leading secondary surgery
Humeral shaft fractures are relatively common injuries and classified according to location fracture morphology. Epidemiological studies improve understanding of injury patterns lay foundations for future research. There only a few published larger epidemiological on humeral fractures.We retrospectively analyzed the medical records adult patients having sustained treated in Helsinki University Hospital between 2006 2016. We recorded patient characteristics, timing mechanism injury,...
This study compares outcomes of surgery and functional bracing for closed humeral shaft fractures after 5 years follow-up.
Two common ways of assessing the clinical relevance treatment outcomes are minimal important difference (MID) and patient acceptable symptom state (PASS). The former represents smallest change in given outcome that makes people feel better, while latter is level at which patients well.We recruited 124 with a humeral shaft fracture to randomised controlled trial comparing surgery nonsurgical care. Outcome instruments included Disabilities Arm, Shoulder, Hand (DASH) score, Constant-Murley two...
Distal radius is the most common site of fracture in children, comprising 23%-31% all paediatric fractures. Approximately one-fifth these fractures are displaced. Completely displaced distal metaphyseal children have traditionally been treated with closed reduction. Recent evidence suggests that correcting shortening over-riding not necessary prepubertal children. To date, no published randomised controlled trial (RCT) has compared treatment by casting bayonet position to reduction and pin...
Medial knee osteoarthritis (OA) is a common health problem resulting in pain and limiting patients' physical activity. After failed conservative treatment, unicompartmental arthroplasty (UKA) high tibial osteotomy (HTO) are possible surgical treatment options for this condition. There paucity of high-quality evidence the literature comparing objective subjective outcomes these procedures. Also, there no agreement on whether procedures provide comparable results late-stage medial OA...
Introduction Shoulder pain is a substantial medical and socioeconomic problem in most societies, affecting the ability to work or carry out leisure time activities as well subsequently influencing physical psychological well-being. According nationwide survey Finland, 27% of population reported shoulder within last 30 days. In clinical practice, imaging findings structural abnormalities are typically thought explain symptoms, even though such also prevalent asymptomatic individuals,...
Aims Though most humeral shaft fractures heal nonoperatively, up to one-third may lead nonunion with inferior outcomes. The Radiographic Union Score for HUmeral Fractures (RUSHU) was created identify high-risk patients nonunion. Our study evaluated the RUSHU’s prognostic performance at six and 12 weeks in discriminating within a significantly larger cohort than before. Methods included 226 nonoperatively treated fractures. We interobserver reliability intraobserver reproducibility of RUSHU...
We conducted a longitudinal observational study over 11 years to identify the risk factors for developing shoulder pain, stiffness, or both.
Background: The Finnish Shaft of the Humerus (FISH) trial compared open reduction and internal plate fixation (ORIF) with functional bracing in adult patients displaced, closed humeral shaft fractures. Here, we compare results randomized clinical (RCT [the cohort]) those cohort who were also eligible but declined randomization (the nonrandomized cohort) to investigate if patients’ treatment preference was associated outcomes during a 2-year follow-up. Methods: A total 321 treated at 2...
Introduction Hallux rigidus is a common problem of pain and stiffness the first metatarsophalangeal joint (MTPJ) caused mainly by degenerative osteoarthritis. Several operative techniques have been introduced for treatment this condition without high-quality evidence comparing surgical to non-surgical care. In trial, most procedure, arthrodesis, will be compared with watchful waiting in management hallux rigidus. Methods analysis Ninety patients (40 years or older) symptomatic MTPJ...
The ischaemic pain of acute compartment syndrome (ACS) can be difficult to discriminate from the linked an associated fracture. Lacking objective measures, decision perform fasciotomy is based on clinical findings and performed at a low level suspicion. Biomarkers muscle cell damage may help identify monitor patients risk, similar current routines for with myocardial infarction. This study will test hypothesis that biomarkers predict ACS in tibial fractures. Patients aged 15-65 years who...
Abstract Background: Two common ways of assessing the clinical relevance treatment outcomes are minimal important difference (MID) and patient acceptable symptom state (PASS). The former represents smallest change in given outcome that makes people feel better, while latter is level at which patients well. Methods: We recruited 124 humeral shaft fracture to a randomised controlled trial comparing surgery nonsurgical care. Outcome instruments included Disabilities Arm, Shoulder, Hand score...