A5084599027- Cardiac Health and Mental Health
- Muscle metabolism and nutrition
- Metabolism, Diabetes, and Cancer
- Adipose Tissue and Metabolism
- Stroke Rehabilitation and Recovery
- Patient Satisfaction in Healthcare
- Cardiovascular and exercise physiology
- Behavioral Health and Interventions
- Metabolism and Genetic Disorders
- Metabolomics and Mass Spectrometry Studies
- Physical Activity and Health
- Cardiac Imaging and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Effects of Exercise
- Primary Care and Health Outcomes
- Acute Myocardial Infarction Research
- Health Systems, Economic Evaluations, Quality of Life
- Peripheral Artery Disease Management
- Chronic Disease Management Strategies
York University
2014-2020
Grace (United States)
2019
Although leucine has many positive effects on metabolism in multiple tissues, elevated levels of this amino acid and the other branched-chain acids (BCAAs) their metabolites are implicated obesity insulin resistance. While some controversies exist about direct effect action skeletal muscle, little is known BCAA metabolites. Here, we first showed that inhibitory insulin-stimulated glucose transport L6 myotubes was dampened when were present, due part to a 140% stimulation basal ( P <...
Exercise maintenance interventions are needed for cardiac rehabilitation (CR) graduates to maintain moderate and vigorous-intensity physical activity (MVPA). We tested an exercise facilitator intervention (EFI) promote compared with usual care (UC) separately in men women.This was a 3-site, randomized (1:1), parallel-group, superiority trial (ECO-PCR). CR were stratified by site sex randomly allocated (concealed). EFI participants received face-to-face introductory session, 5 small-group...
Cardiac patients who engage in ≥150 min of moderate- to vigorous-intensity physical activity (MVPA)/week have lower mortality, yet MVPA declines even following cardiac rehabilitation (CR), and is women. A randomized trial nine socioecological theory-based exercise facilitation contacts over 50 weeks versus usual care (1:1 parallel arms) was undertaken (NCT01658683). The tertiary objective, as presented this paper, test whether the intervention impacted elements, turn their association with...
High protein diets are sometimes prescribed in weight management interventions; however these and amino acids (AA) have been linked to insulin resistance. Much of the attention has on branched‐chain acid (BCAA) leucine because its ability activate mammalian target rapamycin complex 1 (mTORC1). This substrate (S6K1) implicated AA‐induced resistance due their inhibitory serine phosphorylation receptor (IRS1). Since AAs other than present dietary proteins, we examined roles. Valine suppressed...