A5101729150- Peripheral Artery Disease Management
- Aortic aneurysm repair treatments
- Diagnosis and Treatment of Venous Diseases
- Aortic Disease and Treatment Approaches
- Breast Lesions and Carcinomas
- Venous Thromboembolism Diagnosis and Management
- Vascular Procedures and Complications
- Central Venous Catheters and Hemodialysis
- Organ Transplantation Techniques and Outcomes
- Coronary Interventions and Diagnostics
- Breast Cancer Treatment Studies
- Mesenchymal stem cell research
- Cardiac Valve Diseases and Treatments
- Vascular Anomalies and Treatments
- MicroRNA in disease regulation
- Lipoproteins and Cardiovascular Health
- Adipokines, Inflammation, and Metabolic Diseases
- Pulmonary Hypertension Research and Treatments
- Atrial Fibrillation Management and Outcomes
- Liver Disease Diagnosis and Treatment
- MRI in cancer diagnosis
- Cerebrovascular and Carotid Artery Diseases
- Neuroscience of respiration and sleep
- Congenital Diaphragmatic Hernia Studies
- Acute Ischemic Stroke Management
Zhongshan Hospital of Xiamen University
2012-2025
Fudan University
2010-2025
Inspire Institute
2024
University of Electronic Science and Technology of China
2021-2022
Sun Yat-sen Memorial Hospital
2017-2020
Sun Yat-sen University
2017-2020
Key Laboratory of Guangdong Province
2020
Nanjing Children's Hospital
2014-2016
Nanjing Medical University
2014-2016
Xiamen University
2015
Comparisons are limited for immediate-intensive and delayed-intensive statin secondary stroke prevention neuroprotection in patients with acute mild ischemic or transient attack (TIA) from atherosclerosis.
This study utilizes machine learning to analyze the recurrence risk of diabetic foot ulcers (DFUs) in elderly patients, aiming enhance prevention and intervention efforts.
Osteopontin (OPN) has been implicated in tumor development and progression over the last few years. However, prognostic value of OPN overexpression patients with breast cancer remains controversial. We performed a meta‑analysis to investigate association expression clinicopathological characteristics survival patients. A total 8 studies met inclusion criteria were entered meta‑analysis. The data analysis demonstrated that was positively associated lymph node metastasis [pooled odds ratio =...
Objective: To explore abdominal aortic aneurysm (AAA) pathogenesis and identify early diagnostic markers, providing a theoretical basis for novel preventive therapeutic strategies. Methods: Gene expression profiles were retrieved from the Expression Omnibus database (datasets: GSE7084, GSE47472, GSE57691) comprising messenger RNA data samples of 69 patients with AAA 25 non-AAA controls. Data merged normalized; bioinformatics analysis was conducted on upregulated differentially expressed...
Objective The aim of this study was to evaluate the efficacy hybrid therapy and endovascular in treatment complex femoropopliteal Trans-Atlantic Inter-Society Consensus II D（TASC D） lesions involving common femoral artery bifurcation. Methods Patients with TASC D bifurcation for atherosclerotic disease were retrospectively analyzed our institution from July 2018 2023. followed up at 1, 3, 6, 12 months then every year. Clinical data collected, including perioperative follow-up information....
Pupil examination has been used as a basic measure in critically ill patients and great importance for the prognosis management of disease. An automated pupillometer is computer-based infrared digital video system by which accuracy precision pupil are markedly improved. We conducted an observational study assessment with pupillometry clinical liver transplantation settings, including pretransplant evaluations posttransplant surveillance. Our results showed that unconscious (grade 4 hepatic...
Ischemia-reperfusion injury (IRI) following lung transplantation is associated with increased pulmonary inflammatory responses during reperfusion. Mesenchymal stem cells (MSCs) may be able to modulate in IRI. The aim of the present study was evaluate beneficial effects an intravenous infusion bone marrow‑derived MSCs (BMSCs) a rat model IRI induced male Lewis rats by 1‑h ischemia followed 2‑h received phosphate‑buffered saline (PBS) or BMSC at onset Pulmonary determined based on mean blood...
Retrograde access is an alternative approach to endovascular intervention for critical limb ischemia but may be challenging in patients with poor below-knee vessel runoff. Here, we introduce innovative technique based on augmented reality navigation system gain successful retrograde the peroneal artery of 84-year-old woman ischemia. Our result showed that this had potential advantage influencing target selection lower contrast material volume and radiation exposure compared conventional...
Mesenchymal stem cells (MSCs) have been increasingly tested in cell-based therapy to treat numerous diseases. Genetic modification improve MSC behavior may enhance posttransplantation outcome. This study aims test the potential therapeutic benefits of rat bone marrow MSCs overexpressing hypoxia-inducible factor 2α (rMSCsHIF-2α ) a hindlimb ischemia model. PBS, rMSCs, or rMSCsHIF-2α were injected into ischemic hindlimb. Compared with injection PBS transplantation significantly improved blood...
Objectives It has been reported that vascular plugging become a therapeutic alternative to coil embolization in certain cases require occlusion. However, the use of relatively large and rigid delivery sheath may be limiting factor plug use. In this study, we aimed determine safety efficacy novel transcatheter occlusion device with unique design system pig model. Methods The Cera was delivered deployed through FuStar steerable introducer sheath, which can control tip direction during...
Objectives The aim of this study was to report the long-term outcomes proximal thoracic endovascular aortic repair (TEVAR) for chronic Stanford type B dissection (cTBAD). Methods We retrospectively analyzed clinical data 48 cases patients with cTBAD who underwent TEVAR in Zhongshan Hospital Fudan University from January 2010 September 2013. preoperative and postoperative imaging examinations, overall survival rate, aortic-related freedom reintervention rate were collected evaluate remodeling...
Objective To review our multi-institutional experience with endovascular therapy for right subclavian artery occlusive disease and to evaluate the long-term outcomes. Methods We retrospectively evaluated all patients stenosis who underwent between March 2014 September 2022 at two institutions. Patient baseline demographics, lesion characteristics, treatment strategies, in-hospital follow-up outcomes were prospectively collected analyzed. Results Between 2022, 73 The dominant cause of lesions...
Objective: This study aimed to explore whether excessive HIF2α can amplify the impact of human Umbilical Cord Mesenchymal Stem Cell-derived Extracellular Vesicles (hUC-MSC- EVs) on endothelial cells. Methods: In this study, we created HIF2α-overexpressing hUC-MSC-EVs and compared their pro-angiogenic effects with control EVs Human Vein Endothelial Cells (HUVECs). MTT assay Edu staining were used detect viability proliferation ability HUVECs, Transwell tube formation assays cell migration...
Among the various types of aortic dissection, multichanneled dissection (MCAD) differs from classic double-channeled and involves formation an additional false lumen in wall or flaps. It is considered a relatively rare condition with high perioperative mortality morbidity. However, morphological characteristic optimal therapeutic strategy for MCAD has not been fully determined.A 64-year-old man presented to our hospital severe epigastric abdominal pain radiating back that was associated...
Background Endovascular recanalization with venous stenting is the preferred treatment for iliofemoral obstruction. We reviewed our institutional experience and mid-term outcomes endovascular therapy obstruction using Venovo TM Self-expanding Venous Stent (BARD Peripheral Vascular, Inc., Tempe, AZ, USA). Methods Between October 2022 March 2024, patients treated Stents were retrospectively analyzed. Patients monitored at 3, 6, 12 months. The primary endpoint was 12-month patency, defined as...
<h3>Objectives</h3> Patients with type 2 diabetes mellitus (DM), which is characterised by hyperlipidaemia, are liable to more severe and fatal myocardial infarction. Semen Cassiae proved reduce serum unsaturated fatty acids levels. This study was investigate whether the extract reduces ischaemia reperfusion (MI/R) injury, if so, further underlying mechanisms. <h3>Methods</h3> The high-fat diet-fed streptozotocin (HFD-STZ) rat model (type DM model) developed. Age- gender-matched normal rats...
Objective To establish a model of biliary atresia (BA) by infecting neonatal mice with rotavirus (RRV) and explore the mechanisms intra-hepatic bile duct injury liver fibrosis under high expression MCP-1 MIP-2 in BA murine liver.Methods RRV was injected intraperitoneally to induce as experimental group while 10％ fetal bovine serum-Dulbecco's modification Eagle's medium (FBS-DMEM) control group.The were sacrificed at Days 4,7,14 21 their extra-hepatic ducts tissues harvested.The histological...