Małgorzata Zwolińska-Wcisło

ORCID: 0000-0003-4171-2103
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Research Areas
  • Helicobacter pylori-related gastroenterology studies
  • Celiac Disease Research and Management
  • Microscopic Colitis
  • Inflammatory Bowel Disease
  • Gut microbiota and health
  • Digestive system and related health
  • Gastroesophageal reflux and treatments
  • Inflammatory mediators and NSAID effects
  • Liver Disease Diagnosis and Treatment
  • Gastrointestinal motility and disorders
  • Microbial Metabolites in Food Biotechnology
  • Probiotics and Fermented Foods
  • IL-33, ST2, and ILC Pathways
  • Eosinophilic Esophagitis
  • Veterinary medicine and infectious diseases
  • Nutrition and Health Studies
  • Diet, Metabolism, and Disease
  • Genetic factors in colorectal cancer
  • Gastric Cancer Management and Outcomes
  • Potassium and Related Disorders
  • Antifungal resistance and susceptibility
  • Pharmacological Effects of Natural Compounds
  • Galectins and Cancer Biology
  • Medical and Biological Ozone Research
  • Iron Metabolism and Disorders

Jagiellonian University
2016-2025

Institute of Nuclear Physics, Polish Academy of Sciences
2017

Cracow University of Technology
2017

Abstract Background Microscopic colitis (MC) is a chronic inflammatory bowel disease (IBD), characterized by watery diarrhea without blood, fecal urgency and distninct histological features. Symptoms of MC resemble those irritable syndrome (IBS), which can delay accurate diagnosis effective treatment. The potential overlap in symptoms may impede to select management strategies. Methods purpose establishing the Polish Registry Colitis was understand clinical characteristics patients improve...

10.1093/ecco-jcc/jjae190.0505 article EN Journal of Crohn s and Colitis 2025-01-01

Intestinal dysbiosis plays a crucial role in the development of inflammatory bowel disease (IBD), including Crohn's (CD) and ulcerative colitis (UC). The importance bacterial metabolites, such as short-chain fatty acids (SCFAs), succinic lactic acids, well environmental factors that affect their production course IBD, remains unclear. aim this study was to evaluate profile organic stool CD UC patients with different activity. We assessed correlation between used medications, patient's diet,...

10.3390/jcm10204701 article EN Journal of Clinical Medicine 2021-10-13

Although progress has been recently made in understanding of inflammatory bowel diseases (IBD), their etiology is unknown apart from several factors adipose tissue and skeletal muscles such as cytokines, adipokines, myokines were implicated the pathogenesis ulcerative colitis. We studied effect high-fat diet (HFD; cholesterol up to 70%), low-fat (LFD; 10%), normal (total fat 5%) rats with TNBS colitis forced treadmill running exercise (5 days/week) for 6 weeks. In nonexercising HFD rats,...

10.1155/2015/605071 article EN cc-by Mediators of Inflammation 2015-01-01

Growing number of studies suggests link between circadian rhythms and inflammatory bowel diseases (IBD) manifestation. We hypothesize that: 1) IBD are associated with increased eveningness sleep disturbances; 2) disturbances related to more severe symptoms. In total, 129 participants were enrolled this study, divided into three groups: 34 Crohn's disease (CD) patients, 38 ulcerative colitis (UC) patients 57 healthy controls (HC) group. They all fulfilled a questionnaire, consisting the...

10.1080/07420528.2018.1463236 article EN Chronobiology International 2018-05-08

Disturbances in the production of bacterial metabolites intestine have been reported diseases associated with dysbiosis, such as inflammatory bowel (IBDs) that include two conditions: Crohn disease (CD) and ulcerative colitis (UC). Short-chain fatty acids (SCFAs) are main dietary-fiber-derived course intestinal inflammation. In this study, we assessed relationship between body mass index (BMI), type diet used, changes fecal SCFA levels patients IBD. We performed nutritional assessments using...

10.3390/biology11010108 article EN cc-by Biology 2022-01-10

Background: Upadacitinib (UPA) is a new oral selective Janus Kinase (JAK) inhibitor that has shown high efficacy in the treatment of ulcerative colitis (UC). We present data from multicenter real-world study. Methods: To assess UPA, Total Mayo Score (TMS), fecal calprotectin (FC), endoscopy, and intestinal ultrasonography (IUS) were performed. Results: The study population included 76 patients. An amount 26.3% patients biologics small molecules-naive, while 73.7% exposed. By Week 8, 93.4%...

10.3390/jcm14051695 article EN Journal of Clinical Medicine 2025-03-03

Abstract Background This study investigated a possible role of Escherichia coli in propagation and perpetuation the chronic inflammation ulcerative colitis (UC). The lesions UC are located superficially on rectal and/or colonic mucosa. It is suggested that commensal bacteria digestive tract may play pathogenesis UC. Several studies have demonstrated proliferation E. gut patients. An increase number inflamed tissue most probably related to abundance iron ions produced by bacteria. Methods...

10.1186/1471-230x-13-61 article EN cc-by BMC Gastroenterology 2013-04-08

Altered gut regulation, including motor and secretory mechanisms, is characteristic of irritable bowel syndrome (IBS). The severity postprandial symptoms in IBS patients associated with discomfort pain; gas-related such as bloating abdominal distension; abnormal colonic motility. aim this study was to assess the response, i.e., peptide secretion gastric myoelectric activity, constipation-predominant IBS. conducted on 42 (14 males, 28 females, mean age 45.1 ± 15.3 years) healthy participants...

10.1038/s41598-023-36445-1 article EN cc-by Scientific Reports 2023-06-09

Objective. Candida albicans frequently inhabits the gastrointestinal tract of humans leading to candidiasis, especially following suppression gastric acidity, but studies on relation between this fungal infection and pathology are limited due lack convenient animal models resembling in humans. Material methods. We compared effects C. vehicle inoculation secretion healing ulcers induced by acetic acid rats treated with 1) ranitidine (30 mg kg−1 day−1 s.c.) 2) aspirin (ASA) (60 i.g.) or...

10.1080/00365520510011524 article EN Scandinavian Journal of Gastroenterology 2005-02-01

AIM:To determine the e��ect o� non-selective cyclooxygenase (COX) inhibitors, selective COX-2 inhibitors and nitric oxide (NO)-releasing aspirin in healing ulcerative colitis�� METHODS: Rats with 2,4,6 trinitrobenzenesul�onic acid (TNBS)-induced colitis received intragastric

10.3748/wjg.v17.i36.4076 article EN cc-by-nc World Journal of Gastroenterology 2011-01-01

Background. An increasing resistance of Helicobacter pylori strains to antimicrobial agents is the serious therapeutic problem. The aim this study was compare primary and secondary H. isolated between 2006-2008 (data published) 2009-2011 clarithromycin levofloxacin. Material Methods. 220 dyspeptic patients (153 before treatment, 67 after), were enrolled in study. 51 isolated. MIC values levofloxacin determined by E-test method. statistical analysis conducted with χ(2) test Yates correction...

10.1155/2012/418010 article EN cc-by Gastroenterology Research and Practice 2012-01-01

Pyoderma gangrenosum (PG) is an auto-inflammatory dermatosis characterized by lesions that often cause ulcers. We present a case of successful ustekinumab treatment for acute general PG in 31-year-old woman with coexisting Crohn's disease (CD). For month, the patient suffered from skin ulcers, two them deep and necrotic; histopathological examination revealed PG. Treatment included: methylprednisolone, azathioprine, betamethasone, gentamicin zincic ointments, antiseptic compresses,...

10.4081/dr.2023.9630 article EN cc-by-nc Dermatology Reports 2023-05-22
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