A5074367578- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Thermoregulation and physiological responses
- Thermal properties of materials
- Advanced Thermoelectric Materials and Devices
University of St Andrews
2020-2022
Government of the United Kingdom
1989
Genetic recombination in RNA viruses is an important evolutionary mechanism. It contributes to population diversity, host/tissue adaptation, and compromises vaccine efficacy. Both the molecular mechanism initial products of are relatively poorly understood. We used established poliovirus-based vitro assay investigate roles sequence identity structure, implicated or inferred from analysis circulating recombinant viruses, process. In addition, we next-generation sequencing early after cellular...
Abstract Genetic recombination in RNA viruses is an important evolutionary mechanism. It contributes to population diversity, host/tissue adaptation and compromises vaccine efficacy. Both the molecular mechanism initial products of are relatively poorly understood. We used established poliovirus-based vitro assay investigate roles sequence identity structure, both implicated or inferred from analysis circulating recombinant viruses, process. In addition, we next generation sequencing early...
The heat uptake that resulted from immersing the hand and wrist into a water-filled calorimeter maintained at temperatures between 37-40 degrees C was measured under standard conditions in group of eight subjects either sex. rate transfer (W) increased exponentially with temperature function or body size age, but not normalized to mass (W.kg-1) determined by age: best-fit mean values (and 95% confidence limits population) were 6.0 W.kg-1 (3.2-11.2 W.kg-1) an immersion 37 25.4 (13.7-47.0 40...
Positive-strand RNA virus evolution is partly attributed to the process of recombination. Although common between closely genetically related viruses, such as within species Enterovirus genus Picornaviridae family, inter-species recombination rarely observed in nature. Recent studies have shown a ubiquitous process, resulting wide range recombinant genomes and progeny viruses. While not all yield infectious virus, their existence continued during replication critical implications for...