A5032151278- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Catalysis and Hydrodesulfurization Studies
- Catalytic Processes in Materials Science
- Immune Response and Inflammation
- Nanomaterials for catalytic reactions
- Cytokine Signaling Pathways and Interactions
- Gut microbiota and health
- Electrocatalysts for Energy Conversion
- Petroleum Processing and Analysis
- Zeolite Catalysis and Synthesis
- Diagnosis and treatment of tuberculosis
- Social Capital and Networks
- Industrial Gas Emission Control
- Immune Cell Function and Interaction
- Taxation and Compliance Studies
- Seaweed-derived Bioactive Compounds
- Cancer therapeutics and mechanisms
- Blood disorders and treatments
- Biodiesel Production and Applications
- Infectious Diseases and Mycology
- Helicobacter pylori-related gastroenterology studies
- Magnesium Oxide Properties and Applications
- Ginseng Biological Effects and Applications
- Biochemical effects in animals
Central Scientific Research Institute of Tuberculosis Russian Academy of Medical Sciences
2010-2024
Institute of Economics and Industrial Engineering
2018
Siberian Branch of the Russian Academy of Sciences
2018
Technical University of Munich
2014-2016
Centre National de la Recherche Scientifique
2008-2013
Université de Caen Normandie
2011-2013
Laboratoire Catalyse et Spectrochimie
2008-2010
École Nationale Supérieure d'Ingénieurs de Caen
2008-2010
Vladivostok State Medical University
2010
St Petersburg University
2006-2008
The interaction of phenol, anisole, and guaiacol, representatives oxygenate functions present in pyrolysis bio-oils, with oxides such as silica, alumina (pure or doped K F), silica−alumina is investigated by infrared spectroscopy. While phenolic type compounds mainly interact via H-bonding chemisorption their main mode adsorption on alumina. Besides, guaiacol interacts very strongly forming doubly anchored phenates instead monoanchored ones phenol anisole. At temperatures typical...
MoS2 and Ni-promoted catalysts supported on γ-Al2O3, siliceous SBA-15, Zr- Ti-modified SBA-15 were explored for the simultaneous hydrodesulfurization (HDS) of dibenzothiophene (DBT) hydrodenitrogenation (HDN) o-propylaniline (OPA). In all cases, OPA reacted preferentially via initial hydrogenation, DBT was converted through direct sulfur removal. HDN HDS activities are determined by dispersion sulfide phase. Ni promotion increased its activity also rate enhancing hydrogenation. On...
Development of lung granulomata is a hallmark infections caused by virulent mycobacteria, reflecting both protective host response that restricts infection spreading and inflammatory pathology. The role genetics in granuloma formation not well defined. Earlier we have shown mice the I/St strain are extremely susceptible to Mycobacterium tuberculosis but resistant M. avium infection, whereas B6 show reversed pattern susceptibility. Here, directly comparing: (i) characteristics susceptibility...
Abstract The chemical composition and structure of NiMo sulfides supported on γ‐Al 2 O 3 its properties for hydrogenation polyaromatic compounds is explored. presence Ni favors the formation disperse octahedrally coordinated Mo in oxide precursors facilitates reduction during sulfidation. This decreases particle size MoS (measured by transmission electron microscopy) increases concentration active sites up to a Ni/(Mo+Ni) atomic ratio 0.33. At higher loadings, did not decrease further,...
The role of B cells migrating to the lung and forming follicles during tuberculosis (TB) inflammation is still subject debate. In addition their antibody production antigen-presenting functions, secrete different cytokines chemokines, thus participating in complex networks innate adaptive immunity. Importantly, B-cells produce high amounts pleiotropic gp130 cytokine IL-6. Its TB infection remains controversial, partly due fact that IL-6 produced by cell types. To investigate impact on...
The hydrodeoxygenation of model phenol compounds (phenol and 2-ethylphenol) was carried over unpromoted Mo/Al<sub>2<sub/>O<sub>3<sub/> promoted CoMo/Al<sub>2<sub/>O<sub>3<sub/> catalysts. Hydrodeoxygenation proceeds by two pathways:– hydrogenation the aromatic ring followed C<sub>sp3<sub/>-O bond cleavage (HYD pathway, (hydrogenation Csp3-O cleavage));– direct C<sub>sp2<sub/>-O (DDO pathway).Both routes were favored presence Co on catalyst, while alkyl substituent phenolic favors DDO route...
The activation of H2 and H2S on (Ni)MoS2/Al2O3 leads to the formation SH groups with acid character able protonate 2,6-dimethylpyridine. variation in concentrations induced by adsorption shows that both molecules dissociate coordinatively unsaturated cations neighboring S2–. In studied materials, one sulfur vacancy four per 10 metal atoms exist at active edges MoS2 under conditions studied. H2–D2 exchange studies show Ni increases concentration surface hydrogen up 30% optimum loading,...
During tuberculosis (TB) infection, B-lymphocytes migrate to the lungs and form B-cell follicles (BCFs) in vicinity of TB granulomata. B-cell-lacking mice display enhanced susceptibility early depletion infected non-human primates alters T-lymphocyte cytokine responses increases bacterial burdens lungs. However, role B cells during late stages remained unaddressed. Here, we demonstrate that BCFs persist up weeks 25-45 post-challenge TB-resistant C57BL/6 (B6) mice. In hyper-susceptible I/St...
We previously demonstrated that mice of the I/St strain are extremely susceptible to Mycobacterium tuberculosis, as well taxonomically distant intracellular bacteria Chlamydia pneumoniae and Salmonella enterica. To broaden our knowledge about control susceptibility pathogens, we studied infection caused by avium virulent 724 in a panel inbred mouse strains found resistant M. avium. By comparing with B6 mice, (i) much more terms bacterial multiplication lung tissue severity pathology; (ii)...
Abstract Among several quantitative trait loci involved in tuberculosis (TB) control mice, one was mapped within the chromosome 17 segment occupied by H2 complex and another 3 comprising S100A8/9 genes, which encode neutrophil inflammatory factor S100A8/9. Previously, we developed a panel of ‐congenic mouse strains differing small segments major histocompatibility Class II (MHC‐II) region from TB‐susceptible j mice transferred onto genetic background TB‐resistant C57BL/6 ( b ) strain....
To study mycobacterial dissemination and immune-cell trafficking in tuberculosis, we developed a mouse model which introduced 1 microL of Mycobacterium tuberculosis directly into the middle lobe right lung. We investigated kinetics both spread to different anatomical sites recruitment phagocytes activated lymphocytes.Mycobacterial was independent susceptibility infection identical H-2-congenic strains with high low resistance tuberculosis. In resistant mice, phagocytic cells uninfected lung...
To dissect the role of part H2 complex comprised MHC-II genes in control tuberculosis (TB) infection, we previously established a panel recombinant congenic mouse strains bearing different segments H2j haplotype on B6 (H2b) genetic background. Fine mapping, gene sequencing and assessment TB phenotypes resulted identification H2-Ab as major factor control.We further narrowed interval by spotting new recombination event, newly DNA configuration establishing strain B6.I-103 which j/b occurred...
FTIR spectra of CO adsorbed at low temperatures on CsX and KX zeolites, unlike those for CsZSM5 or NaX, reveal bands wavenumbers below the position free molecule. In accordance with electrostatic model, are attributed to molecules which form side-on complexes basic framework oxygen ions. Low values entropy changes adsorption, obtained these from analysis temperature dependence intensity different pressures, testify rotational mobility anions.
The effect of H2S upon the acidity MgO surface has been investigated using FTIR spectra adsorbed dimethylpyridine (2,6-DMP) and CO as test molecules. In presence weakly bound H2S, 2,6-DMP reveal Brønsted acidity. Adsorption perturbs OH groups from only in or aprotic molecules such CO2 SO2. This infers that these are activated by acidic which act source protons. Thus, weak adsorption compounds, SO2, CO2, can lead to dramatic enhancement surface.