- Angiogenesis and VEGF in Cancer
- Mathematical Biology Tumor Growth
- Hernia repair and management
- Vascular Malformations and Hemangiomas
- Thermoregulation and physiological responses
- Airway Management and Intubation Techniques
- Cardiovascular Syncope and Autonomic Disorders
- Bone health and osteoporosis research
- Case Reports on Hematomas
- Cardiac tumors and thrombi
- Nail Diseases and Treatments
- Pericarditis and Cardiac Tamponade
- Metabolism and Genetic Disorders
- Traumatic Ocular and Foreign Body Injuries
- Infectious Diseases and Tuberculosis
- Hedgehog Signaling Pathway Studies
- Genetic and rare skin diseases.
- Sports injuries and prevention
- Muscle and Compartmental Disorders
- Prostate Cancer Treatment and Research
- Hip and Femur Fractures
- Ultrasound in Clinical Applications
- Biliary and Gastrointestinal Fistulas
- Sarcoma Diagnosis and Treatment
- Infectious Disease Case Reports and Treatments
National Institute for Health Research
2024
University of Birmingham
2024
Royal Free London NHS Foundation Trust
2017-2023
Royal London Hospital
2022
Barnet Hospital
2020-2022
University College London
2001-2021
University College Hospital
2016-2021
Harefield Hospital
2020
Royal Brompton & Harefield NHS Foundation Trust
2020
We have examined the anatomy of pelvic (inferior hypogastric) plexus in six male cadavers, paying particular attention to gross anatomical landmarks that might aid locating it and used immunohistochemistry study small branches supply prostate gland. The was found two finger breadths lateral third anterior sacral foramina, lying deep a line drawn from vertebra, conventional level recto-sigmoid junction, palpable posterior superior surface pubic symphysis. Immunohistochemical staining showed...
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A 77-year-old-woman with poorly controlled type 2 diabetes mellitus presented a 1-week history of anorexia and nausea. Blood tests revealed leukocytosis associated left shift (white cells 21,140 neutrophil count 17,380 per cubic millimeter) elevation the levels C-reactive protein (21.0 mg/dL). In emergency department, she collapsed. Arterial blood gas analysis metabolic lactic acidosis pH 7.23 lactate 13.5 mmol liter. Abdomino-pelvic computed tomography demonstrated intramural bladder in...
A 37-year-old male presented to the emergency department with sudden onset left calf pain. He had been playing tennis when he felt a snapping sensation in posterior ankle. no medical history and recent of antibiotic use. There was palpable Achilles tendon gap present ankle examined dorsiflexion, squeezing ipsilateral did not result plantarflexion (Figure 1 Supporting Information Video S1). The Simmonds–Thompson test positive leg (Supporting This indicates rupture is absence foot squeezed....
Most commonly caused by trauma, basal skull fractures present with a range of clinical signs. These include periorbital ecchymosis, as seen in this case, well rhinorrhea, otorrhoea and post-mastoid ecchymosis. Suspected cases must be managed appropriate imaging medical or surgical treatment indicated.
An 84-year-old man presented to the emergency department (ED) with painless genital bruising that had suddenly developed preceding night. There was no history of abdominal pain or trauma and other medical note. The patient's blood pressure 133/88 mm Hg, heart rate 93 beats/min. Examination revealed well-demarcated suprapubic ecchymosis, on left side shaft penis scrotum (Figure 1). abdomen soft, non-tender, not distended. aorta palpable, a mass appreciable. Laboratory investigations...
A 64-year-old woman with known osteoarthritis of the hips presented a history recently increasing left-sided hip pain. Pelvic plain radiographs were undertaken to assess for possibility fracture. These revealed degenerative changes at joints and two dentiform calcifications in pelvis (Figure 1, arrows), raising concern dermoid tumor. Computed tomography contrast was subsequently undertaken, demonstrated an ovarian cystic lesion measuring 12 cm maximally, teeth periphery (blue fat-fluid...
An 89-year-old woman attended the emergency department with vomiting and constipation of 1-week duration associated progressively increasing abdominal pain. Examination demonstrated generalized tenderness no evidence peritonism. Laboratory studies revealed a white cell count 12,200 per cubic millimeter (4000–11,000). Abdominal radiography was undertaken due to suspicion bowel obstruction Rigler's triad: dilated loops small (Figure 1, blue arrow) on left abdomen, pneumobilia red arrow), faint...
Abstract Understanding how drugs are delivered to diseased tissue, and their subsequent spatial temporal distribution, is a key factor in the development of effective, targeted therapies. However, interaction between pathophysiology tissue individual therapeutic agents can be complex, vary significantly individuals. In cancer, suboptimal dosing resulting from poor delivery cause reduced treatment efficacy, upregulation resistance mechanisms even stimulate growth. Preclinical tools better...
Campbell University School of Osteopathic Medicine is using a variety medical simulation systems in the training its students. The simulators allow students to learn and practice skills controlled environment, they enable faculty challenge with broader range conditions than might ordinarily be encountered during training.