A5077443927- Musculoskeletal pain and rehabilitation
- Health Systems, Economic Evaluations, Quality of Life
- Meta-analysis and systematic reviews
- Pain Management and Placebo Effect
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Delphi Technique in Research
- Health Policy Implementation Science
- Pain Mechanisms and Treatments
- Pain Management and Treatment
- Advanced Causal Inference Techniques
- Ethics in Clinical Research
- Spine and Intervertebral Disc Pathology
- Complementary and Alternative Medicine Studies
- Clinical practice guidelines implementation
- scientometrics and bibliometrics research
- Health and Medical Research Impacts
- Health Sciences Research and Education
- Stroke Rehabilitation and Recovery
- Sports injuries and prevention
- Behavioral Health and Interventions
- Academic Publishing and Open Access
- Myofascial pain diagnosis and treatment
- Pain Management and Opioid Use
- Pediatric Pain Management Techniques
- Medical Malpractice and Liability Issues
Neuroscience Research Australia
2017-2025
UNSW Sydney
2017-2025
Impact
2022-2023
Government of Western Australia Department of Health
2023
The University of Notre Dame Australia
2023
Nuffield Orthopaedic Centre
2020-2022
University of Oxford
2020-2022
Center for Effective Global Action
2022
Harvard University
2022
University of Exeter
2020
Mediation analyses of randomized trials and observational studies can generate evidence about the mechanisms by which interventions exposures may influence health outcomes. Publications mediation are increasing, but quality their reporting is suboptimal.
<h3>Importance</h3> The effects of altered neural processing, defined as altering networks responsible for perceptions pain and function, on chronic remains unclear. <h3>Objective</h3> To estimate the effect a graded sensorimotor retraining intervention (RESOLVE) intensity in people with low back pain. <h3>Design, Setting, Participants</h3> This parallel, 2-group, randomized clinical trial recruited participants (>3 months) nonspecific from primary care community settings. A total 276...
Mediation analysis is a method that quantifies how health exposures, such as medical interventions, change patient outcomes. Evidence generated from mediation analyses important for intervention development and clinical policy decision making. has many applications require specific careful consideration design, conduct, analysis, interpretation. This article outlines motivations, effect types, causal assumptions, estimation, reporting guidance studies aim to improve their interpretation,...
Open science remains vital to the progress and functioning of global research enterprise. Published in 2015, Transparency Openness Promotion Guidelines (TOP 2015) was developed as a policy framework enhance verifiability empirical claims journal articles. It has been widely used adopted by publishers academic journals, but despite its uptake, concerns have raised about aspects TOP 2015 implementation. In response above, purpose this manuscript is introduce an official update Guidelines. The...
Background Observational studies are increasingly used to inform health decision-making when randomised trials not feasible, ethical or timely. The target trial approach provides a framework help minimise common biases in observational that aim estimate the causal effect of interventions. Incomplete reporting using limits ability for clinicians, researchers, patients and other decision-makers appraise, synthesise interpret findings clinical public practice policy. This paper describes...
How much are the reductions in pain intensity and improvements physical function from Pilates exercise mediated by changes catastrophising kinesiophobia?This was a secondary causal mediation analysis of four-arm randomised controlled trial testing dosage (once, twice or thrice per week) against booklet control.Two hundred fifty-five people with chronic low back pain.All analyses were conducted R software (version 4.1.2) following preregistered plan. A directed acyclic graph constructed to...